HSP70 expression in Biomphalaria glabrata snails exposed to cadmium
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2017
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Ecotoxicology and Environmental Safety
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In this study, the effects of the heavy metal cadmium on the stress protein HSP70 are investigated in freshwater mollusks Biomphalaria glabrata. Adult snails were exposed for 96 h to CdCl2 at concentrations ranging from 0.09 to 0.7 mg L-1 (LC50/96 (h) = 0.34 (0.30-0.37). Time and concentration-dependent increases in the expression of HSP70 were observed at sub-lethal levels in the immunoblotting assay. Further, an increased survival to a lethal heat shock was observed in animals pre-exposed to a nonlethal concentration of cadmium, evidencing the induction of acquired tolerance. The present study demonstrated the inducibility of B. glabrata HSP70 by cadmium, a relevant environmental contaminant, at non-lethal levels, providing evidences that the assessment of HSP70 in B. glabrata can be regarded as a suitable biomarker for ecotoxicological studies.
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CANTINHA, REBECA da S.; BORRELY, SUELI I.; OGUIURA, NANCY; PEREIRA, CARLOS A. de B.; RIGOLON, MARCELA M.; NAKANO, ELIANA. HSP70 expression in Biomphalaria glabrata snails exposed to cadmium. Ecotoxicology and Environmental Safety, v. 140, p. 18-23, 2017. DOI: 10.1016/j.ecoenv.2017.02.026. Disponível em: http://repositorio.ipen.br/handle/123456789/27841. Acesso em: 19 Apr 2024.
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