Alternative for the quality control of antivenom production proposed by Lonomia obliqua caterpillars using analytic techniques
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2018
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BRAZILIAN MEETING ON NUCLEAR PHYSICS, 41th
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Resumo
The caterpillars Lonomia obliqua Walker (L. obliqua) species, commonly found in southern Brazil, is very
poisonous and can cause severe damage in human (haemorrhagic e®ects) after the contact that can lead to death
[1]. The ¯rst case of poisoning (registered in Brazil) occurred in 1989 and the average number of accidents is
closer to 500/year [2]. Nowadays, the Butantan Institute (Research Center at S~ao Paulo city, Brazil) is active in
the production of this antiveneom in Latin America; it is the only producer of antilonomic serum. However, in
the last two years, this caterpillar has been found in other regions due, mainly, to the expansion and destruction
of natural ecosystems provide their growth in all regions of the country. To ensure that the antivenom produced
(considering the di®erent origins) can be used for the manufacture of unaltered antilonomic serum, it is necessary
to standardize this antidote. We intend to standardize the serum obtained from di®erent regions of origin using
X-Ray Fluorescence (XRF). The experimental conditions using the compact XRF spectrometers (X-123SDD,
Amptek) were optimized. The results will be compared and validated with INAA analysis.
Como referenciar
LEÃO, ANICARINE R.; ZAMBONI, CIBELE B.; SILVA, DALTON G.N. da; MENDONÇA, RONALDO Z.; SIMONS, SIMONE M. Alternative for the quality control of antivenom production proposed by Lonomia obliqua caterpillars using analytic techniques. In: BRAZILIAN MEETING ON NUCLEAR PHYSICS, 41th, September 2-6, 2018, Maresias, SP. Abstract... São Paulo: Sociedade Brasileira de Física, 2018. p. 1-1. Disponível em: http://repositorio.ipen.br/handle/123456789/30113. Acesso em: 25 Apr 2024.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.