Methylene blue-mediated photoinactivation of Staphylococcus aureus assisted by gold nanoshells
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2019
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BRAZILIAN CONGRESS ON BIOMEDICAL ENGINEERING, 26th
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Gold nanoshells (silica core/gold shell) have fascinating
optical extinction spectrum within visible to near infrared
range. In this work, we investigate the optical properties of
Au nanoshells and evaluate the feasibility of their use on
photodynamic therapy. Three dimensional finite element
simulation and experimental analyses were explored on
the assessment of the localized surface plasmon resonance
spectrum and spatial distribution of the electromagnetic
field enhancement near metallic nanoshells. In addition,
the interaction of Au nanoshells with methylene blue
(MB) photosensitizer was appraised, and 3.2—fold metal
enhanced single oxygen generation was observed. Lastly,
we investigate the effects of MB-mediated photoinactivation
on Staphylococcus aureus assisted by gold nanoshells.
The use of nanoshells on the photoinactivation
procedure reduced 3 the required illumination time for
total eradication of bacterial cells. Our results indicate that
Au nanoshells are promising candidates to enhance the
photodynamic effect on bacterial cells.
Como referenciar
FAROOQ, SAJID; CORREIA, THAMARA T. da S.; YOSHIMURA, TANIA M.; PEREIRA, SAULO de T.; RIBEIRO, MARTHA S.; ARAUJO, RENATO E. Methylene blue-mediated photoinactivation of Staphylococcus aureus assisted by gold nanoshells. In: COSTA-FELIX, RODRIGO (ed.); MACHADO, JOÃO C. (ed.); ALVARENGA, ANDRÉ V. (ed.). In: BRAZILIAN CONGRESS ON BIOMEDICAL ENGINEERING, 26th, October 21-25, 2018, Armação de Buzios, RJ. Proceedings... Singapore: Springer Nature Singapore, 2019. p. 841-845. (IFMBE Proceedings, volume 70/2). DOI: 10.1007/978-981-13-2517-5_130. Disponível em: http://repositorio.ipen.br/handle/123456789/30148. Acesso em: 18 Apr 2024.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.