A biological study of gelatin-PVA based scaffold functionalized with albumin for biomedical purposes
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2022
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CONGRESSO BRASILEIRO DE ENGENHARIA E CIÊNCIA DOS MATERIAIS, 24.
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Biomaterials have been designed for tissue reconstruction, bone regeneration and cell culture, and
functionalized with presence of proteins, nanoparticles, peptides and other components to improve
the biocompatibility for instance. This work shows a biological study of gelatin-PVA based scaffold
with controlled pore size and functionalized with albumin for biomedical purposes. The in vitro
study comprises cytotoxicity, cell adhesion and proliferation assessment. In practical terms, the
gelatin-PVA scaffold crosslinked and sterilized by gamma radiation followed by freeze-drying was
evaluated by cytotoxicity, adhesion and proliferation tests. The cytotoxicity results showed that the
biomaterial produced was non-toxic, and adhesion and proliferation assays showed that the
material was suitable for tissue engineering. The presence of albumin did not present a significant
impact on the cell performance, at the assayed concentration.
Como referenciar
VARCA, J.O.; KLINGBEIL, F.; NOGUEIRA, K.M.; LIMA, C.S.; CRUZ, C.C. da; FREITAS, L.F.; VARCA, G.H.; MATHOR, M.B.; LUGAO, A.B. A biological study of gelatin-PVA based scaffold functionalized with albumin for biomedical purposes. In: CONGRESSO BRASILEIRO DE ENGENHARIA E CIÊNCIA DOS MATERIAIS, 24., 6-10 de novembro, 2022, Águas de Lindóia, SP. Resumo... Disponível em: http://repositorio.ipen.br/handle/123456789/33823. Acesso em: 18 Apr 2024.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.