• IPEN-DOC 26090

  ROLINDO, N.C. ; TESSARO, A.P.G. ; SMITH, R.B. ; CAMPOS, C.; MARUMO, J.T. ; VICENTE, R. . Disused sealed radioactive sources: inventory and characterization at IPEN. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26089

  MORAES, MARCIA C.D. ; PEREIRA, DAISA L. ; ANA, PATRICIA A. da; FREITAS, ANDERSON Z. de ; ZEZELL, DENISE M. . Optical attenuation coefficients obtained through OCT correlates to microhardness in dental human enamel irradiated with Nd: YAG and submitted to demineralization in vitro. In: RECHMANN, PETER (Ed.); FRIED, DANIEL (Ed.) SPIE PHOTONICS WEST; SPIE BIOS, February 2-7, 2019, San Francisco, USA. Abstract... Washington, USA: SPIE, 2019. (Proceedings SPIE 10857, Lasers in Dentistry XXV).

  Abstract: This work aims was to correlate the changes in the optical attenuation coefficients obtained through the OCT technique with the values obtained in Knoop sectional microhardness tests over time in dental human enamel samples irradiated with the Nd: YAG laser and Acid Phosphate Fluoride (APF), aiming the prevention of caries lesions in vitro. After Ethical Committee approval, 160 enamel samples, obtained from 40 human tooth molars, were divided into 4 groups: Control group (where no treatment was performed); Fluoride group (APF - fluoride phosphate acidulated for 4 minutes); Fluoride-Laser group: APF followed by irradiation with Nd:YAG laser (DE = 84.9 J/cm2, contact mode, with the use of carbon paste as photoabsorver); Laser-fluoride group (irradiation with Nd:YAG laser followed by APF). The samples of all groups were subjected to pH cycling during 20 days. On days 5, 10, 15 and 20, 10 samples from each group were removed from the cycling for the Knoop sectional microhardness test. Two samples of each group, at each time, were randomly selected for the analysis with FTIR-ATR (Fourier transform infrared spectroscopy associated with attenuated total reflection technique). The analysis by ATR-FTIR showed changes in the chemical composition of the samples of the irradiated groups in relation to Control and Fluoride group. There was correlation between the values of sectional microhardness tests and the measured optical attenuation coefficient by OCT in irradiated dental enamel, showing that the association between fluoride application and Nd:YAG laser irradiation is an important tool for the prevention of tooth enamel demineralization.

  

• IPEN-DOC 26088

  MAYNARD, ISABELLA F.N.; CAVALCANTI, ELIANE B.; MARTINS, ELAINE A.J. ; SILVA, LARISSA L. da ; PIRES, MARIA A.F. ; MARQUES, MARIA N.. Avaliação da presença de desreguladores endócrinos em água subterrânea e tratada em uma área rural. In: ARENZON, ALEXANDRE (Ed.); NUNES, MARIA E.T. (Ed.); BOTTA, CLARICE M.R. (Ed.); ESPINDOLA, EVALDO L.G. (Org.); NOVELLI, ANDREA (Org.) CONGRESSO BRASILEIRO DE ECOTOXICOLOGIA, 15th, 1-4 de setembro, 2018, Aracaju, SE. Resumo expandido... Campinas: Sociedade Brasileira de Ecotoxicologia, 2018. p. 672-674.

  

• IPEN-DOC 26073

  ALBANO, A.M.S. ; ARTHUR, V. . Efeito da radiação gama na inibição da germinação de ervilha in natura (Pisum sativum L.). In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26072

  CAMPOS, R.F. ; CAMPOS, V.P. ; MITAKE, M.B. ; ARAUJO, E.B. . Analise dosimétrica de um laboratório de radiobiodistribuição in vivo usando CaSO4:Dy. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26071

  SILVA, T.M.; KODAMA, Y. ; SOMESSARI, S.L. ; OMI, N.M. ; NORMANTON, K.A.F.; VASQUES, F.M.F. ; DUARTE, C.L. ; SAMPA, M.H.O. ; CALVO, W.A.P. . Desenvolvimento de procedimentos e metodos de monitoração individual e de área em uma unidade móvel de irradiação por feixe de elétrons. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26070

  COELHO, ANASTACIA L.L.P.B.; PINHEIRO, ANGELICA L.L.P.; SIMPSON, STEPHANIE C.; ZEITUNI, CARLOS ; ROSTELATO, MARIA E.C.M. . A radiação ionizante como forma de tratamento nas mulheres com câncer de colo de útero em Araguaína –TO nos anos de 2000 a 2015. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  Abstract: O câncer vem se apresentando como um grave problema de saúde pública em todo mundo as sociedades globais, especialmente em países subdesenvolvidos. Em 2005, de um total de 58 milhões de mortes ocorridas no mundo, o câncer foi responsável por 7,6 milhões (13%). Desse total, mais de 70% ocorreram em países de média ou baixa renda. Atualmente, o câncer é a segunda causa de morte no Brasil (10,3% do total), excluídas as causas indeterminadas, ficando atrás somente de doenças cardiovasculares . Para 2018, há uma estimativa de 16.370 novos casos, sendo que, 2.300 se encontram na região Norte do país. O câncer de colo uterino é o segundo tipo de câncer mais frequente entre as mulheres em todo o mundo. A sua frequência, entretanto, é bastante variável de acordo com o desenvolvimento do país estudado, sendo que 83% dos casos registrados no mundo acontecem em países em desenvolvimento, onde o risco cumulativo é de 1,5% aos 65 anos. Este trabalho trata-se de um estudo descritivo, retrospectivo, quantitativo-interpretativo, com analise de dados secundários do período de 2000 a 2015 do Registro Hospitalar de Câncer pelo Sistema de Informação em Saúde (SIS-RHC), vinculado ao Hospital Regional de Araguaína. Os dados foram tabulados em planilhas eletrônicas do excel onde foram obtidas variáveis estatísticas e frequência para análise. . Foram analisadas 2.664 mulheres com câncer de Colo de Útero no Hospital Regional de Araguaína. Sendo divididas em 17 variáveis na “Ficha de Tumor”; o histórico de bebida alcoólica e de tabaco apresentaram as maiores porcentagens de ausência de preenchimento (mais de 31%). Em seguida, 25,9% das fichas não tiveram o preenchimento da escolaridade. De uma forma geral, pode-se notar que das 17 informações utilizadas neste estudo, 55,7% das fichas continham todas as informações e 12, 2% tinham 4 ou mais informações ausentes. Observa-se entre o tempo de diagnóstico e tratamento que as mulheres diagnosticadas tardiamente apresentaram, em média, tempos maiores entre as duas ações. a maioria das pacientes tiveram um diagnóstico tardio, com isso a radioterapia se tornou a principal forma de tratamento.

  

• IPEN-DOC 26069

  ALVARENGA, T.S. ; POLO, I.O. ; PEREIRA, W.W.; CALDAS, L.V.E. . Anisotropia da fonte de 241AmBe do laboratório de calibração com nêutrons do IPEN. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26068

  LITVAC, D. ; CALDAS, L.V.E. . Caracterização dosimétrica do LiF-nrpb para calibração de aplicadores clínicos de betaterapia. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26067

  SANTOS, W.S.; NEVES, L.P.; PERINI, A.P.; CALDAS, L.V.E. . Uso de modelagem computacional para avaliação da exposição médica e ocupacional durante procedimento de cardiologia intervencionista. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26066

  CASTRO, M.C. ; SILVA, N.F. ; CALDAS, L.V.E. . Some characterization tests for an extrapolation chamber in CT standard beams in a specific chamber depth. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26065

  ANTONIO, P.L. ; CALDAS, L.V.E. . Comportamento do sinal TL/OSL e PTTL/PTOSL após tratamento térmico pós-irradiação com fonte de 60Co, em amostras de LiF:Mg,Ti e CaSO4:Dy. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26064

  LIMA, B.L.; ALMEIDA, J.S. ; POTIENS, M.P.A. ; PELISSONI, R.A.; SAPIENZA, M.T.; BUCHPIGUEL, C.A.; WILLEGAIGON, J.. Evaluation of biokinetics and dosimetry in [131I]-NaI therapies: whole-body images quantification versus lower limb region. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26063

  TAVARES, P.S.; RODRIGUES JUNIOR, O. ; CAMPOS, L.L. . Princípio de investigação do dosímetro Fricke Gel modificado utilizando um equipamento de CT Óptico. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26062

  SAUEIA, C.H.R. ; NISTI, M.B. ; MAZZILLI, B.P. . Determinação de Cs-137 e radionuclídeos naturais em sedimentos do Sistema Estuário da Baixada Santista, Brasil. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26061

  SILVA, N.F. ; SILVA, T.F.; CASTRO, M.C. ; LUZ, H.N. da; CINTRA, F.B. ; CALDAS, L.V.E. . Simulation of a TH-GEM based detector for standard mammography-quality beam dosimetry using the MCNP5 code. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26060

  SILVA, E. ; SANTOS, L.R. ; ASSEMANY, L.P.F. ; POTIENS, M.P.A. . Evaluation of the performance of radioprotection ionization chambers used in radiometric survey of radiology clinical systems. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26059

  NISTI, M.B. ; CAMPOS, M.P. ; SILVA, G.M. ; MAZZILLI, B.P. . Determinação da taxa de exalação do 222Rn no solo do IPEN. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26058

  TAMURA, T.M.; SOUZA, R.E.; NEVES, L.P.; PERINI, A.P.; SANTOS, W.S. . Cálculo de fator de conversão para dose absorvida em atividade de navegação utilizando o método Monte Carlo e um simulador antropomórfico virtual. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26057

  CORREIA, R.W. ; ROSTELATO, M.E.C.M. ; ZEITUNI, C.A. . Estudo e calibração de detector HPGe para análise radionuclídica de iodo-125. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26056

  ABREU, R.T. ; ANGELOCCI, L.V. ; NOGUEIRA, B.R. ; SANTOS, H.N. ; ZEITUNI, C.A. ; ROSTELATO, M.E.C.M. . Dose-rate constant evaluation of a new 192-Ir brachytherapy source using Monte-Carlo and experimental parameters. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26055

  BAPTISTA, T.S. ; ZEITUNI, C.A. ; RODRIGUES, B. ; MOURA, J. ; ROSTELATO, M.E. . Efficiency test on three types of sanitizers for cleaning sealed radioactive sources for brachyterapy. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26054

  ANDRADE, M.A.B.; ALVES, C.O.; FIN, A.P.C.; SOARES, F.A.P.; SAVI, M. ; POTIENS, M.P.A. . Visual impact of infill percentages for 3D printed radiologic simulators. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26053

  PRADO, E.S.P. ; MIRANDA, F.S.; PETRACONI, G.; POTIENS JUNIOR, A.J. . Tratamento de rejeitos radioativos compactáveis aplicando a tecnologia plasma para redução volumétrica. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26052

  MARTINS, E.W. ; BUENO, L.K. ; POTIENS, M.P.A. . Implementação de uma instalação para implantação da nova metodologia de calibração de ativímetros. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26051

  DIAS, A.J.R. ; VILELA, A.N. ; VICENTE, R. ; DELLAMANO, J.C. . Acidentes radiológicos: dados que auxiliam a proteção radiológica. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26050

  OLIVEIRA, J.J.; VICENTE, R. . Relevância radiológica relativa: Angra 1 e 2. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26049

  TESSARO, A.P.G. ; SMITH, R.B. ; ROLINDO, N.C. ; VICENTE, R. . Opening the Goiania accident unburied waste packages. In: INTERNATIONAL JOINT CONFERENCE RADIO, September 16-20, 2019, São Paulo, SP. Resumo expandido... Maringá, PR: Sociedade Brasileira de Proteção Radiológica, 2019.

  

• IPEN-DOC 26048

  GASPARIAN, P.B.R. ; YOSHIMURA, E.M.; UMISEDO, N.K.; CAMPOS, L.L. ; MALTHEZ, A.L.M.C.. Study of the dosimetric properties of CaSO4:Dy using OSL technique. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 326-326.

  

• IPEN-DOC 26047

  SILVA, A.M.B.; JUNOT, D.O. ; CALDAS, L.V.E. ; SOUZA, D.N.. TL and OSL characterization of CaSO4:Tb, CaSO4:Tb,Ag, and CaSO4:Tb,Ag(NP). In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 321-321.

  

• IPEN-DOC 26046

  POLO, IVON O. ; CALDAS, LINDA V.E. . SOL-GEL α-Al2O3 detectors: TL and OSL response to beta radiation beams. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 317-317.

  

• IPEN-DOC 26045

  JUNOT, DANILO O. ; SOUZA, DIVANIZIA N.; CALDAS, LINDA V.E. . The influence of the preparation route in the TL/OSL signal of CaSO4:Eu,Ag samples. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 310-310.

  

• IPEN-DOC 26013

  ANTONIO, PATRICIA L. ; CALDAS, LINDA V.E. . Phototransfer analysis on TL and OSL responses of LiF:Mg,Ti (TLD-100) after exposure to 60Co radiation. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 302-302.

  

• IPEN-DOC 26012

  ANTONIO, PATRICIA L. ; CALDAS, LINDA V.E. . Influence of the thermal treatment on the PTTL and PTOSL signals from different natural materials. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 301-301.

  

• IPEN-DOC 26044

  VILLANI, D. ; MORENO, C.S.; SAKURABA, R.K.; GONÇALVES, V.D.; CAMPOS, L.L. . Optically stimulated luminescence dosimetry characterization with clinical photon beams and LINAC measurements. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 299-299.

  

• IPEN-DOC 26043

  VENEZIANI, G.R. ; MATSUSHIMA, L.C.; GAGLIARDO, K.M.; CARVALHO, T.P.A.; SAKURABA, R.K.; CAMPOS, L.L. . Development of phantom using 3D printer for veterinary radiosurgery. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 297-297.

  

• IPEN-DOC 26042

  SILVA, NATALIA F. ; SILVA, TIAGO F.; CASTRO, MAYSA C. ; LUZ, HUGO N. da; CINTRA, FELIPE B. ; CALDAS, LINDA V.E. . Simulation of geometry and materials of the TH-GEM based detector for radiation dosimetry. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 253-253.

  

• IPEN-DOC 26041

  BARRERA, GERARDO R.; ALMEIDA, ADRIEL S.; JUNOT, DANILO O. ; SOUZA, DIVANIZIA do N.. Synthesis and TL and OSL characterization of (MgB2O4-MgB4O7): Ce:Li and (MgB2O4-MgB4O7): Dy:Li glasses for dosimetry. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 216-216.

  

• IPEN-DOC 26040

  NASCIMENTO, BRUNA C.; FRIMAIO, AUDREW ; BARRIO, RAMON M.M.; SIRICO, ANA C.A.; COSTA, PAULO R.. Comparative analysis of the transmission properties of radiologically equivalent materials. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 212-212.

  

• IPEN-DOC 26039

  FRIMAIO, AUDREW ; NASCIMENTO, BRUNA C.; BARRIO, RAMON M.M.; CAMPOS, LETICIA L. ; COSTA, PAULO R.. X-ray spectrometry applied for determination of linear attenuation coefficient of tissue-equivalent materials. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 207-207.

  

• IPEN-DOC 26038

  CASTRO, MAYSA C. ; SILVA, NATALIA F. ; SANTOS, LUCAS R. ; CINTRA, FELIPE B. ; CALDAS, LINDA V.E. . Evaluation of an extrapolation chamber for dosimetry in computed tomography beams using Monte Carlo code (MCNP5). In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 204-204.

  

• IPEN-DOC 26037

  SANTOS, CARLA J.; SANTOS, WILLIAM S.; NEVES, LUCIO P.; BELINATO, WALMIR; CALDAS, LINDA V.E. ; PERINI, ANA P. . Dose determination in pediatric interventional cardiology procedures: Monte Carlo approach. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 191-191.

  

• IPEN-DOC 26036

  SANTOS, WILLIAM S.; SANTOS, CARLA J.; NEVES, LUCIO P.; BELINATO, WALMIR; CALDAS, LINDA V.E. ; PERINI, ANA P. . Numerical dosimetry in brachytherapy to variable mama sizes using two different types of 125I seeds. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 190-190.

  

• IPEN-DOC 26035

  NEVES, LUCIO P.; BORGES, ADRIANE; SOARES, MARIA R.; BELINATO, WALMIR; SANTOS, WILLIAM S.; CALDAS, LINDA V.E. ; PERINI, ANA P. . Computational dosimetry in a pediatric iCAT procedure using a virtual antropomorphic phantom. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 189-189.

  

• IPEN-DOC 26034

  SOUZA, LUCAS W.G.; POZZO, LORENA ; PERINI, ANA P. ; BELINATO, WALMIR; SANTOS, WILLIAM S.; CALDAS, LINDA V.E. ; NEVES, LUCIO P.. Monte Carlo simulation of microPET/CT occupational exposure using 18F and 68Ga tracers. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 179-179.

  

• IPEN-DOC 26033

  SILVA, ROGERIO M.V.; BELINATO, WALMIR; SANTOS, WILLIAM S.; PERINI, ANA P. ; NEVES, LUCIO P.; SANTOS, CARLA J.; SOUZA, DIVANIZIA N.. Low cost electron irradiator using 90Sr+90Y sources. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 178-178.

  

• IPEN-DOC 26032

  MATSUSHIMA, L.C.; VENEZIANI, G.R. ; SAKURABA, R.K.; CAMPOS, L.L. . Verification of absorbed doses using thermoluminescent detectors and mapping of isodose curves in IMRT planning. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 177-177.

  

• IPEN-DOC 26031

  MARTINS, ELAINE W. ; CARDOSO, JOÃO V.; POTIENS, MARIA da P.A. . Paediatric phantom performance evaluation in computed tomography radiation standard beams. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 176-176.

  

• IPEN-DOC 26030

  AMARAL, CAIO E.S.; LIMA, CAIO L.; BELINATO, WALMIR; NEVES, LUCIO P.; PERINI, ANA P. ; SANTOS, WILLIAM S.; ALMEIDA, EDSON P.B. de; NAVARRO, MARCUS V.T.. Simulation of a laboratory for the radiation detectors calibration. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 103-103.

  

• IPEN-DOC 26029

  LIMA, CAIO L.; AMARAL, CAIO E.S.; BELINATO, WALMIR; NEVES, LUCIO P.; PERINI, ANA P. ; SANTOS, WILLIAM S.; ALMEIDA, EDSON P.B. de; NAVARRO, MARCUS V.T.. Computational simulation of the detectors designed for computer tomography. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 102-102.

  

• IPEN-DOC 26028

  CORTEZ, BRUNA ; CHUBACI, JOSE F.D.; GOMES, MONISE B. ; OLIVEIRA, LETICIA M. ; SATIRO, LUCAS C. ; ROCCA, RENE R.; ARIZACA, EDY E.C.; WATANABE, SHIGUEO. Dating sediments from a terrace found in Iguape - Icapara in southeast coast in the state of São Paulo, Brazil. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 85-85.

  

• IPEN-DOC 26027

  GOMES, MONISE B. ; CORTEZ, BRUNA ; OLIVEIRA, LETICIA M. de ; CARMO, LUCAS S. do ; CHUBACI, JOSE F.D.; ROCCA, RENE R.; WATANABE, SHIGUEO. Dating of shells from Pântano da Malhada, Rio de Janeiro. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 81-81.

  

• IPEN-DOC 26026

  GROPPO, DANIELA P. ; SARAIVA, CRYSTIAN W.C.; CALDAS, LINDA V.E. . Determination of the penumbra width of Elekta SRS Cone Collimator for 6 MV FF and 6 MV FFF energies using Gradient-Based Edge Detection. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 72-72.

  

• IPEN-DOC 26025

  FONSECA, T.C.F.; SENIWAL, B.; MENDES, A.M.; BELO, M.C.L.; LACERDA, M.A.S.; MENDES, M.B.; PAIXÃO, R.L.; JOANA, G.S.; SANTANA, P.; MARQUES, J.; SQUAIR, L.P.; ANTUNES, P. ; YORIYAZ, H. ; BASTOS, F.. MCMEG: InterComparison exercise on radiotherapy assessment prostate dose. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 66-66.

  

• IPEN-DOC 26024

  SOUZA, PAULO R.D. de ; RODRIGUES, BRUNA T. ; MACHADO, LUCAS K. ; ZEITUNI, CARLOS A. ; ROSTELATO, MARIA E.C.M. . Evaluation of dose received in adjacent organs in the dosimetric plan of lung cancer. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 64-64.

  

• IPEN-DOC 26023

  SOARES, MARIA R. ; SANTOS, WILLIAM S.; NEVES, LUCIO P.; PERINI, ANA P. ; MAIA, ANA; BELINATO, WALMIR; CALDAS, LINDA V.E. . Computational modeling of thyroid shields and lead eyewear and the impact on the absorbed doses of eye lens and thyroid gland in CBCT exams. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 56-56.

  

• IPEN-DOC 26022

  BELINATO, W.; ALMEIDA, E.P.B. de; NEVES, L.P.; PERINI, A.P. ; CALDAS, L.V.E. ; SANTOS, W.S.. Occupational exposures in PET procedures with 18F-FDG. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 55-55.

  

• IPEN-DOC 26021

  ASSEMANY, LADYJANE P.F. ; RODRIGUES JUNIOR, ORLANDO ; POTIENS, MARIA da P.A. . Evaluation of 3D printing filaments for construction of a pediatric phantom for dosimetry in CBCT. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 54-54.

  

• IPEN-DOC 26020

  ALVARENGA, TALLYSON S. ; POLO, IVON O. ; PEREIRA, WALSAN P.; SILVA, FELIPE S.; FONSECA, EVALDO S.; CALDAS, LINDA V.E. . Contribution of the scattered radiation on the neutron beam fluence in the neutron calibration laboratory at IPEN. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 48-48.

  

• IPEN-DOC 26019

  ALMEIDA, S.B. ; VILLANI, D. ; SAKURABA, R.K.; REZENDE, A.C.P.; CAMPOS, L.L. . Comparison between Al2O3:C pellets and DIODEs for TSEB in vivo dosimetry using an anthropomorphic phantom. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 47-47.

  

• IPEN-DOC 26018

  SILVA-CARRERA, BETZABEL N. ; CANO, NILO F.; WATANABE, SHIGUEO. Low dose radiation dosimetry using natural blue quartz crystal by TL technique. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 39-39.

  

• IPEN-DOC 26017

  COSTA, NATHALIA A. ; POTIENS, MARIA da P.A. ; PATALLO, ILEANA S.; DIMITRIADIS, ALEX. Phantom development and implementation for Gamma Knife® dosimetry. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 24-24.

  

• IPEN-DOC 26016

  CARMO, L.S. do ; WATANABE, S. ; SILVA, R.J.; CHUBACI, J.F.D.. Dating aeolian sediments using ESR Ti-Li center in quartz, TL and OSL-SAR: Dama Branca, study. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 23-23.

  

• IPEN-DOC 26015

  GONZALES-LORENZO, CARLOS; WATANABE, SHIGUEO; BUENO, CARMEN ; KODAIRA, SATOSHI; NASCIMENTO, LUANA. CaSiO3 polycrystal for neutron, proton and carbon detection. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 20-20.

  

• IPEN-DOC 26014

  VILLANI, D. ; DORES, D.S. das; SILVA, V.R. da; COSTA, Z.M. da; CAMPOS, L.L. . Er+Ag-doped phosphate glass as luminescent dosimeters. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 325-325.

  

• IPEN-DOC 26011

  SANTOS, W.S. ; NEVES, L.P. ; PERINI, A.P.; BELINATO, W.; CALDAS, L.V.E. . Evaluation of polymer gels using Monte Carlo simulations. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 80-80.

  

• IPEN-DOC 26010

  SILVA, EZEQUIEL da ; ASSEMANY, LADYJANE P.F. ; POTIENS, MARIA da P.A. . Performance evaluation of a cilindrical ionization chamber used in radiation protection measurements of diagnostic radiology clinical systems. In: RUBIO, MARCELO (Ed.); TIRAO, GERMAN (Ed.) INTERNATIONAL SYMPOSIUM ON RADIATION PHYSICS, 14th, October 7-11, 2018, Córdoba, Argentina. Abstract... Córdoba: Centro de Excelencia en Productos y Procesos, 2018. p. 60-60.

  

• IPEN-DOC 26009

  CASTRO, PEDRO A.A. de ; ZEZELL, DENISE M. ; MORAIS, MYCHEL R.P.T.; ZORN, TELMA M.. Semi quantitative evaluation of skin burn wound healing: ATR-FTIR study. In: ENCONTRO DE OUTONO DA SOCIEDADE BRASILEIRA DE FÍSICA, 42nd, 26-31 de maio, 2019, Aracaju, SE. Resumo... São Paulo: Sociedade Brasileira de Física, 2019.

  Abstract: The role of skin wound healing the biochemical mechanisms are still not fully understood and spectroscopy may shine some light on this information. The Fourier Transform Infrared spectroscopy coupled with Attenuated Total Re°ectance (ATR-FTIR) has been demonstrated potential to monitor the biomolecule activity upon biological samples. This work aims to evaluate the feasibility of using ATR-FTIR to discriminate burned skin throughout wound stages. Water vapor at 90±C was applied to the dorsum of Wistar rats resulting in standardized third-degree burns. Tissue samples were collected after 3±, 7±, 14± and 21 days post burn injury. For the acquisition of the spectra, 150 scans were averaged with a resolution of 4 cm¡1 and wavenumbers ranging from 4000 to 400 cm¡1. Analysis of the spectra was calculated using MATLABR°R2015a (MathWorks, Natick, MA) software. Fingerprint region (900 - 1800 cm¡1) and high wavenumber (2800 - 3000 cm¡1) of spectra were o®set-corrected and vector normalized. Area under the curve (AUC) of collagen (1236 cm¡1), amide II (1540 cm¡1), amide I (1632 cm¡1) and lipid (2852 cm¡1) of each group were performed by integration method. The FTIR results exhibit the high biochemical activity of the tissue in the 14o post burn injury when it is compared with control group which correspond to the stage when the new tissue formation is still ongoing. The lipid content decrease in the 21 day, which suggest that the metabolic activity and structural reorganization decrease as the wound healing progress. For future works, micro-FTIR imaging will be used spatially discriminate the bands.

  

• IPEN-DOC 26008

  AMARAL, MARCELLO M.; ARAUJO, JEANN C.R.; ANTUNES, ANDREA; MONTE, ADAMO F.G.; CARA, ANA C.B. de ; FREITAS, ANDERSON Z. de ; ZEZELL, DENISE M. . Phantom validation of optical attenuation coefficient estimation model with depth resolution for Optical Coherence Tomography. In: ENCONTRO DE OUTONO DA SOCIEDADE BRASILEIRA DE FÍSICA, 42nd, 26-31 de maio, 2019, Aracaju, SE. Resumo... São Paulo: Sociedade Brasileira de Física, 2019.

  Abstract: Optical Coherence Tomography (OCT) has been used for imaging and analyzes over a broad number of applications.[1-3] Besides its use for morphological analysis [3] the OCT signal has been used to determine the optical attenuation coe±cient of biological samples for classi¯cation and diagnostic proposes. [1,2] The most common model for estimating the optical attenuation coe±cient based on OCT signal relies on the Lambert- Beers law. It usually assumes a constant attenuation coe±cient value over the image range or over a selected range, losing the in-depth resolution on OCT. Previous published work on literature developed a model to esti- mate the attenuation coe±cient with depth resolution [4], however it assumes that the light is totally attenuated within the image depth range failing for membrane like samples. We present a model that, using the tissue sample transmittance as input, remove this limitation and to estimate the depth-resolved optical attenuation coe±cient. This method allows us to obtain an image of tissue optical properties instead of that from intensity contrast, guiding diagnosis and tissues di®erentiation, extending its application from thin to tick samples. The performance of our method was tested with the assistance of a home built single layer and multi-layer phantoms ( 100¹m each layer). These optical phantoms are composed of a substrate polydimethylsiloxane (PDMS), Zinc- Phthalocyanine (ZnPc) dye as chromophores, and TiO2 as scattering agent. The optical attenuation coe±cient ranges from 0:9 to 2:32 mm¡1, measured using an integrating sphere followed by the Inverse Adding Doubling processing technique. We show that the estimated depth-resolved attenuation coe±cient recovers the reference values, with a error deviation of 7 %.

  

• IPEN-DOC 26007

  LIMA, CASSIO ; BYRNE, HUGH; CORREA, LUCIANA; ZEZELL, DENISE . Molecular pathology via infrared spectral imaging for skin cancer diagnosis. In: ENCONTRO DE OUTONO DA SOCIEDADE BRASILEIRA DE FÍSICA, 42nd, 26-31 de maio, 2019, Aracaju, SE. Resumo... São Paulo: Sociedade Brasileira de Física, 2019.

  Abstract: Fourier Transform Infrared (FTIR) spectroscopy is a rapid and label-free analytical technique that provide information about the overall biochemical pro¯le of biological samples based on the vibrations of its basic molecular components (carbohydrates, proteins, lipids and nucleic acids) that are infrared active. The potential biomedical applications of FTIR spectroscopy as a tool for cancer diagnosis have been well demonstrated over the last years. However, most studies have focused on evaluate the diagnostic ability of FTIR by comparing healthy tissue to cancers on advanced stage and few studies have centered on evaluating the early stages of cancer. Thus, the present study aims to demonstrate the ability of FTIR spectroscopy to discriminate healthy skin from advanced skin cancer (squamous cell carcinoma) as well as from early stages of malignancy using the information retained by spectral data. Cutaneous neoplastic lesions were chemically-induced on Swiss mice using a well-stablished two-stage carcinogenesis protocol. Healthy tissue was collected from animals non-exposed to chemicals and di®erent disease stages were obtained by varying the exposure time of animals to carcinogenenic factors. Tissue sections were obtained from formalin-¯xed para±n-embedded (FFPE) and placed on calcium °uoride substrates. FTIR hyperspectral images were acquired in transmission mode over mid-infrared spectral region and compared using Principal Components Analysis (PCA) associated to Linear Discriminant Analysis (PC-LDA). Satisfactory data discrimination (accuracy, sensitivity and speci¯city) was achieved by PC-LDA and the variables responsible by classi¯cation were evaluated in order to assess the spectral changes of skin components during the transition of healthy into diseased state. Our ¯ndings demonstrate the potential of FTIR spectroscopy not only for skin cancer diagnosis, but also to evaluate the biochemical events triggered by cancer without requiring laborious and time-consuming procedures or expensive labeled probes as biomarkers.

  

• IPEN-DOC 26006

  PEREIRA, DAISA L. ; CASTRO, PEDRO A.A. ; GOMES, GABRIELA V. ; ZAMATARO, CLAUDIA B. ; ZEZELL, DENISE M. ; RIBEIRO, HENRIQUE B.; MATOS, CHRISTIANO J.S.; ANA, PATRICIA A.. Heat-induced depth of Nd:YAG laser irradiation in biological hard tissues. In: ENCONTRO DE OUTONO DA SOCIEDADE BRASILEIRA DE FÍSICA, 42nd, 26-31 de maio, 2019, Aracaju, SE. Resumo... São Paulo: Sociedade Brasileira de Física, 2019.

  Abstract: Confocal Raman spectroscopy is a non-destructive and non-invasive technique which provides surface Raman spectra and depth images of biological structures contactless with the sample, with no use of ionizing radiation to penetrate in the sample under analysis. These characteristics allow its experimental use without any side e®ects to the sample. The depth images are obtained by Raman microscopy and are related to the characteristics of the tissues. This study aims to characterize irradiated hard tissues and correlate the depth reached by the heat of the laser irradiation with the obtained images. For this, thirty 8 mm2 blocks of bovine enamel and bovine root dentin, were randomized into 6 groups: G1- enamel untreated; G2- enamel irradiated with Nd:YAG micropulsed laser (1064 nm, 10 Hz- Lares Research R°) using a coal paste as photoabsorber; G3- enamel irradiated with Nd:YAG nanopulsed laser (1064 nm, 20 Hz, Brilliant, Quantel Laser) using a coal paste as photoabsorber; G4-G6 (bovine root dentin in the same conditions of treatment of G1-G3). The measurements were performed in three di®erent depth regions of the cubic shaped samples: region A- left corner above of the sample, region B- middle of the sample and Region C- right corner below of the sample. The area under the phosphate, carbonate, amide I, II, and III bands were calculated. The Raman spectra of the Nd:YAG irradiated samples detected a reduction in all the organic components of the enamel after laser irradiation. Previous studies of our group demonstrated that di®erences in carbonate substitution in the apatite lattice are related to the apatite instability and demineralization susceptibility. Considering that carbonate free apatite is less susceptible to acid attack, the results of this study suggest that Nd:YAG lased enamel can be more resistant to caries, in a direct correlation to the thickness of the treated area. It was found that for micropulsed Nd:YAG laser, the heat induced depth was 10 § 2 ¹m and for nanopulsed laser the heat induced depth was 8 § 3 ¹m. So, it is possible to correlate the heat penetration depth of the laser irradiation with the images obtained by the confocal Raman.

  

• IPEN-DOC 26005

  ZAMATARO, CLAUDIA B. ; KUCHAR, NIELSEN G. ; SCAPIN, MARCOS A. ; ZANINI, NATHALIA ; CASTRO, PEDRO ; RABELO, THAIS F. ; JUVINO, AMANDA C. ; ZEZELL, DENISE . Calcium analysis from gamma sterilized human dentin and enamel. In: ENCONTRO DE OUTONO DA SOCIEDADE BRASILEIRA DE FÍSICA, 42nd, 26-31 de maio, 2019, Aracaju, SE. Resumo... São Paulo: Sociedade Brasileira de Física, 2019.

  Abstract: Gamma radiation changes the patients0 oral cavity undergoing radiotherapy. Alterations cause an unsaturated environment of calcium and phosphate into the oral cavity. After approval of the Ethics Committee, 20 hu- man teeth were sectioned to obtain 20 human enamel and 20 dentin samples, polished plane. Samples were randomized in the irradiated group and control group (untreated). Then, the treatment group was irradiated with 25:0 kGy at the 60Co multipurpose irradiator. After the gamma irradiation, Fourier Transformed Infrared Spectroscopy (FTIR), percentage of surface microhardness loss (%SMHL) and Scanning Electron Microscopy (SEM) were performed. At the end, acidic biopsies were performed to quantify the concentration of calcium present in the samples. FTIR showed that the molecular structure of HA of the enamel is similar to the non- irradiated, with no formation or loss of molecular compounds occurring. X-ray °uorescence at enamel samples was performed. Microscopic morphological analysis did not shown signi¯cant di®erences. Surface microhardness is an indirect indicator of the mineral content of the samples. The mean obtained was 258:2 (38:8) KHN within the hardness spectrum of the healthy natural enamel. The compounds present in the samples and the values of the ratios of Calcium and Phosphate oxides and relation between the elements Calcium and Phosphorus. The ratio of the most stable oxides shows a variation with linear correlation. In the enamel, the ratio (Ca/P) shows a change in the elemental content with linear correlation (R2 = 1). These ¯ndings lead us to a new hypothesis of behaviour of the HA crystal versus gamma irradiation. On the other hand for the irradiated dentin, the Knoop hardness number was within the range of the spectrum similar to that of natural dentin of human origin. X-ray °uorescence shows that irradiated dentin has great similarity with natural dentin from the point of view of chemical composition. SEM analyses showed that there was no thermal damage or interprismatic morpho- logical changes in the hydroxyapatite structure of human dental dentin outside the buccal environment when using doses of gamma irradiation up to 25 kGy.

  

• IPEN-DOC 26004

  OLIVEIRA, R.R. ; FUJIMOTO, T.G. ; MUCCILLO, E.N.S. . Estudo da densificação, estrutura e microestrutura do SrTiO3 contendo praseodímio. In: CONGRESSO BRASILEIRO DE CERÂMICA, 63rd, 4-7 de agosto, 2019, Bonito, MS. Resumo... 2019.

  Abstract: Materiais com estrutura do tipo perovsquita apresentam interessantes propriedades físicas que podem ser escritas em termos de distorções estruturais associadas a mudanças na composição química juntamente com os defeitos existentes na rede cristalina. Isso permite uma ampla faixa de aplicação em dispositivos eletrônicos tais como: supercacitores; dispositivos para armazenamento de energia; atuadores piezoelétricos; dentre outras. Particularmente, os materiais baseados em titanato de estrôncio (STO) tem sido intensamente estudados, sobretudo sua estrutura e microestrutura. A estrutura cristalina pode ser alterada por meio de substituições químicas com a introdução de aditivos. Neste trabalho, foi realizado o estudo estrutural e microestrutural do STO contendo diferentes teores de praseodímio. As amostras foram preparadas mediante mistura de óxidos convencional, partindo do STO e Pr6O11 comerciais. As amostras de STO contendo 0,025; 0,050; 0,075 e 1% mol de Pr foram conformadas por compactação uniaxial e isostática e sinterizadas à 1500 ºC durante 6 horas. A caracterização das amostras sinterizadas foi realizada mediante densidade aparente pelo método de Arquimedes, microscopia eletrônica de varredura (MEV) para o estudo da morfologia superficial (em amostras polidas) e difração de raios X para determinação da estrutura por meio de refinamento pelo método de Rietvield. Os resultados mostram que as amostras apresentam densidade próxima à teórica (95%), com exceção da contendo 1% mol do aditivo (83%). As micrografias obtidas por MEV mostram que houve um tênue aumento no tamanho médio de grãos de 28 m em STO para 30 m nas amostras contendo praseodímio. Nos parâmetros de rede obtidos pelo refinamento dos padrões de difração de raios X foi observado que as amostras foram cristalizadas no sistema cúbico e não possuem alterações significativas nas diferentes proporções de aditivos variando de 3,904 à 3,906 Å.

  

• IPEN-DOC 26003

  MUCCILLO, E.N.S. ; FUJIMOTO, T.G. ; SOUZA, J.P. . Avaliação da microestrutura do SrTiO3 comercial e obtido por reação em estado sólido. In: CONGRESSO BRASILEIRO DE CERÂMICA, 63rd, 4-7 de agosto, 2019, Bonito, MS. Resumo... 2019.

  Abstract: Materiais com estrutura do tipo perovskita tem diversas aplicações na indústria eletro-eletrônica, como por exemplo, em dispositivos eletrônicos, capacitores, ou transdutores piezoelétricos. Dentre os principais materiais utilizados com esse tipo de estrutura que vem sendo amplamente estudado destaca-se o titanato de estrôncio. A microestrutura deste tipo de perovskita é essencial para obtenção das propriedades de interesse para estas aplicações. Portanto, neste trabalho foi realizado o estudo da microestrutura do titanato de estrôncio por meio de microscopia eletrônica de varredura e de força atômica. As amostras foram preparadas utilizando o titanato de estrôncio obtido por meio de reação em estado sólido e comercial. Os compactos cerâmicos foram sinterizados a 1500ºC por 6 h de patamar. As amostras foram caracterizadas por meio de densidade, microscopia eletrônica de varredura, espectroscopia de energia dispersiva (EDS) e microscopia de força atômica. Os resultados mostraram que as amostras sintetizadas apresentaram regiões com forma triangular onde foi identificada uma alta concentração de Sr por meio de EDS. A amostra produzida a partir do material comercial apresentou grãos heterogêneos e através do mapa de adesão foi possível observar texturas diferentes dos grãos. As amostras possuem densidades acima de 99% da densidade teórica.

  

• IPEN-DOC 26002

  FERREIRA, L.A.S. ; REIS, S.L. ; MUCCILLO, E.N.S. . Estabilização de fase e microestrutura da zircônia-céria obtida por reação em estado sólido. In: CONGRESSO BRASILEIRO DE CERÂMICA, 63rd, 4-7 de agosto, 2019, Bonito, MS. Resumo... 2019.

  Abstract: Materiais cerâmicos à base de zircônia estabilizada na fase tetragonal têm sido extensivamente estudados e propostos para diversas aplicações devido suas destacadas propriedades termomecânicas. A zircônia contendo 12 mol% em céria (12Ce-TZP) possui estrutura tetragonal, alta resistência à fratura e estabilidade térmica. Este trabalho tem como objetivo verificar o efeito da sinterização na estabilização da fase tetragonal e na microestrutura da 12Ce-TZP preparada por reação em estado sólido. As amostras de 12Ce-TZP foram preparadas pelo método de mistura dos óxidos reagentes seguida de sinterização em diversas temperaturas. As fases cristalinas, densificação e microestrutura foram analisadas por difração de raios X, medidas de densidade hidrostática e microscopia eletrônica de varredura, respectivamente. O teor de fase monoclínica foi quantificado utilizando o método dos polimorfos. Amostras com fase única tetragonal foram obtidas para sinterizações a 1400 °C e densidades próximas à teórica (> 99%) para amostras sinterizadas a 1500 °C.

  

• IPEN-DOC 26001

  GROSSO, R.L. ; MUCHE, D.N.F.; CASTRO, R.H.R.; MUCCILLO, E.N.S. ; DILLON, S.. Testes mecânicos de nano-compressão por MET in-situ em zircônia estabilizada. In: CONGRESSO BRASILEIRO DE CERÂMICA, 63rd, 4-7 de agosto, 2019, Bonito, MS. Resumo... 2019.

  Abstract: Zircônia-escândia (ScZ) possui grande interesse tecnológico para aplicação como eletrólito sólido devido a sua maior condutividade iônica entre os materiais à base de zircônia. No entanto, as propriedades mecânicas de ScZ são pouco conhecidas, principalmente, devido à instabilidade de fase, que limita a aplicação desse material. Considerando que a estrutura cúbica tipo fluorita é dependente do tamanho dos grãos e pode ser estabilizada em nanoescala, nesse trabalho, foram investigadas as propriedades mecânicas de amostras densas de ScZ nanoestruturadas. Amostras ScZ foram obtidas por sinterização assistida por campo elétrico, pelo método, recentemente proposto, que utiliza punções deformáveis. Esse método de sinterização inibe o crescimento de grãos devido às baixas temperaturas utilizadas e elimina a porosidade residual devido à aplicação de alta pressão. Amostras de ZrO2 contendo teor molar de 10% de Sc2O3 foram sintetizadas pelo método de coprecipitação de hidróxidos, calcinadas e sinterizadas em baixas temperaturas (700 a 860 °C) e elevadas pressões (1,4 e 2 GPa). Foram produzidas amostras cúbicas policristalinas com tamanho médio de grãos entre 8 e 17 nm. Testes mecânicos de compressão foram realizados por microscopia eletrônica de transmissão in situ em nanopilares de seção transversal quadrada preparados por feixe de íons focalizado. As propriedades mecânicas foram avaliadas em função do tamanho médio de grãos. Foi observada uma considerável melhoria nas propriedades mecânicas em amostras nanoestruturadas de ScZ. O limite de escoamento aumentou de 1,9 para 4,9 GPa com a diminuição do tamanho médio de grãos de 50 para 13 nm. Os valores de limite de escoamento seguem a relação de Hall-Petch para amostras com tamanho médio de grãos de até 13 nm, onde ocorre a inversão na relação de Hall-Petch.

  

• IPEN-DOC 26000

  REIS, S.L. ; CARVALHO, S.G.M. ; MUCCILLO, E.N.S. ; MUCCILLO, R. . Densificação de céria-samária por meio de sinterização sem pressão assistida por campo elétrico AC. In: CONGRESSO BRASILEIRO DE CERÂMICA, 63rd, 4-7 de agosto, 2019, Bonito, MS. Resumo... 2019.

  Abstract: A solução sólida céria-samária é uma das principais candidatas para aplicação como eletrólito sólido em células a combustível de óxido sólido, devido sua alta condutividade iônica em temperaturas intermediárias de operação (500-750 °C). Um dos problemas ainda não solucionados é sua relativamente baixa sinterabilidade. Altas temperaturas de sinterização, em geral acima de 1500 °C, são necessárias para obter densificação com impermeabilização a gases (> 92% da densidade teórica). Em altas temperaturas pode ocorrer redução de Ce4+ para Ce3+, com consequente aumento na condutividade eletrônica. No entanto, a utilização de métodos de sinterização não convencionais como a sinterização sem pressão assistida por campo elétrico é uma das estratégias para diminuir a temperatura de sinterização e otimizar as propriedades. Este trabalho tem como objetivo avaliar os efeitos do método de sinterização isotérmica assistida por campo elétrico AC durante o patamar em uma temperatura fixa. Foram realizados experimentos variando campo elétrico, tempo de aplicação do campo e limite de corrente elétrica. Os resultados mostraram que é possível densificar a céria-samária em temperaturas inferiores às convencionais por meio de sinterização sem pressão assistida por campo elétrico. O aumento do valor do campo elétrico promoveu diminuição nos valores de resistividade intragranular e intergranular. O aumento na temperatura de aplicação do campo elétrico resultou em amostras com condutividade elétrica maior em relação à amostra sinterizada convencionalmente em 1500 °C/2 h.

  

• IPEN-DOC 25999

  REIS, S.L. ; MUCCILLO, E.N. . Influence of calcium addition on the electrical conductivity of samarium doped ceria. In: INTERNATIONAL CONFERENCE & EXPOSITION ON ADVANCED CERAMICS AND COMPOSITES, 42nd, January 21-26, 2018, Daytona Beach, Florida, USA. Abstract... Westerville, OH, USA: The American Ceramic Society, 2018. p. 97-97.

  Abstract: Ceria-based ceramics have been proposed to be used as solid electrolyte in solid oxide fuel cells operating at intermediate (500-750°C) temperatures, due to their high ionic conductivity. Samarium ion is recognized as one of the most reliable dopants for cerium oxide because of its lower association energy with oxygen vacancies. One challenge posed to ceria-based solid electrolytes is how to improve sinterability, avoiding high temperatures to attain good densification. Thermal treatments at high temperatures may reduce Ce4+ to Ce3+, favoring electron transport and generation of micropores in the sintered electrolyte. Introduction of a second additive is a usual approach to overcome these constraints. In this work calcium ion was chosen as the second additive. Sm0.2-xCaxCe0.8O1.9-x/2 compositions, with x = 0, 0.025, 0.05, 0.1, 0.15 and 0.2, were prepared by solid-state reaction, and the influence of the additive content on densification and ionic conductivity was investigated. All compositions were found to have cubic fluorite-type structure. The optimal composition was Sm0.175Ca0.025Ce0.8O1.888, which showed a relative density of 97%, single phase and higher ionic conductivity than the Sm0.2Ce0.8O1.9 parent electrolyte.

  

• IPEN-DOC 25998

  SOUZA, J.P. ; MUCCILLO, E.N. . Ionic conductivity and phase stabilization in zirconia-scandia-europia. In: INTERNATIONAL CONFERENCE & EXPOSITION ON ADVANCED CERAMICS AND COMPOSITES, 42nd, January 21-26, 2018, Daytona Beach, Florida, USA. Abstract... Westerville, OH, USA: The American Ceramic Society, 2018. p. 97-97.

  Abstract: Zirconia-8 mol% yttria is widely used as electrolyte in solid oxide fuel cells, due to its high ionic conductivity and good mechanical and chemical properties. Nevertheless, scandia-stabilized zirconia is recognized as exhibiting the highest ionic conductivity among zirconia-based solid electrolytes. Stabilization of the high symmetry and high ionic conductivity cubic phase in this system is non-trivial. Introduction of a second additive (or dopant) is a usual strategy to overcome that constraint. In this work, europium oxide has been added to 10 mol% scandia-stabilized zirconia (10ScSZ) aiming full stabilization of the cubic structure at room temperature. The influence of europia addition (up to 1.25 mol%) on phase stabilization and ionic conductivity of 10ScSZ was investigated by differential scanning calorimetry and impedance spectroscopy. The higher is the fraction of europia into solid solution the lower is the temperature of the endothermic event due to phase transition. The cubic phase is fully stabilized at room temperature for 1 mol% europia addition. The grain and total ionic conductivity show typical Arrhenius behavior. The magnitude of the total conductivity increases with increasing europia addition.

  

• IPEN-DOC 25997

  MUCCILLO, R. ; MUCCILLO, E.N. . Non-conventional joining of a ceramic solid oxide fuel cell to a metallic interconnect. In: INTERNATIONAL CONFERENCE & EXPOSITION ON ADVANCED CERAMICS AND COMPOSITES, 42nd, January 21-26, 2018, Daytona Beach, Florida, USA. Abstract... Westerville, OH, USA: The American Ceramic Society, 2018. p. 208-208.

  Abstract: Co-generation of energy (heat and electric power) with ceramic solid oxide fuel cells requires consolidation of anode-electrolyte- cathode single cells with a dense electrolyte and porous anode and cathode. The consolidation is usually achieved by sintering the three-layer single cells according to special procedures to produce flat square shape cells. Non-conventional consolidation of several ceramic materials used in energy-conversion devices has been done with success in several ceramic materials by electric field-assisted pressureless sintering, producing porous or dense components. The same approach has been tried in a flat single solid oxide fuel cell with yttria-stabilized zirconia solid electrolyte, lanthanum strontium manganite cathode and yttria-stabilized zirconia/nickel oxide anode with promising results, opening new routes for future low cost production of these devices. There is still a challenge in using that technique for joining ceramic single cells to metallic interconnector, one of the research areas of Dr. Mrityunjay Singh. Our efforts now are directed to carry out experiments aiming the joining of ceramic single cells to metallic interconnects by application of electric fields.

  

• IPEN-DOC 25996

  DAMATTO, SANDRA R. ; MADUAR, MARCELO F. ; LEONARDO, LUCIO; BORGES, LARISSA R.; OLIVEIRA, GABRIEL F.M.; SILVA, SANDRA M.C.S. da. Radioatividade natural em castanhas. In: CONGRESSO MULTIPROFISSIONAL DO CENTRO UNIVERSITÁRIO SÃO CAMILO, 3rd, 9-10 de novembro, 2018, São Paulo, SP. Resumo... São Paulo: Centro Universitário São Camilo, 2018. p. 297-297.

  Abstract: INTRODUÇÃO: A radioatividade natural está presente em todos os compartimentos do ecossistema terrestre, como ar, solo, água, alimentos e no ser humano, originada dos radionuclídeos naturais encontrados na crosta terrestre. Os radionuclídeos naturais mais abundantes na natureza são os das séries de decaimento radioativo do 238U e 232Th, e 40K. A radioatividade natural chega até o homem pela cadeia alimentar, por meio dos alimentos vegetais e animais, fazendo com que todos os alimentos possuam diferentes concentrações dos radionuclídeos naturais. Vários tipos de castanhas são utilizadas em dietas e, dentre este grupo de alimentos, destaca-se a castanha-do-brasil, por ser um alimento que possui as maiores concentrações de atividade dos radionuclídeos naturais 226Ra, 228Ra e 40K. OBJETIVO: Determinar as concentrações de atividade dos radionuclídeos naturais 40K, 226Ra, 228Ra e 228Th em castanhas consumidas pela população brasileira: castanha-do-brasil, coco, pecã brasileira, castanha de baru, castanha de caju e pinhão cru e cozido. MATERIAIS E MÉTODOS: A determinação dos radionuclídeos naturais foi realizada por espectrometria gama, utilizando um detector de germânio hiperpuro (HPGe) associado a um sistema eletrônico e tempo de medida de 250.000 s. RESULTADOS: As maiores concentrações de atividade de 226Ra foram obtidas na castanha-do-brasil e de 40K na amostra de coco. Somente na amostra de castanha-do-brasil foram determinadas as concentrações de atividade de 228Th e 228Ra. Pode-se observar que a amostra de pinhão cozido apresentou menores valores de concentração de atividade para os radionuclídeos determinados. CONCLUSÃO: No presente trabalho foram determinadas as concentrações de atividade dos radionuclídeos naturais 40K, 226Ra, 228Ra e 228Th em amostras das castanhas: castanha de baru, castanha de caju, castanha- do-brasil, coco, pecã brasileira e pinhão, cru e cozido. Os valores determinados de 40K e 226Ra para a castanha-do-brasil encontraram-se de acordo com a literatura, e as determinações das concentrações de atividade nas outras amostras contribuíram para um levantamento de banco de dados para cálculo de dose devido ao consumo das demais castanhas.

  

• IPEN-DOC 25995

  DEL SANTOS, NAYARA D.; AUGUSTO, VICTORIA M.; SARTORI, LUCIANA P.; LEONARDO, LUCIO; DAMATTO, SANDRA R. . Caracterização elementar em amostras de tartarugas de água doce Trachemys scripta elegans. In: CONGRESSO MULTIPROFISSIONAL DO CENTRO UNIVERSITÁRIO SÃO CAMILO, 3rd, 9-10 de novembro, 2018, São Paulo, SP. Resumo... São Paulo: Centro Universitário São Camilo, 2018. p. 15-15.

  Abstract: INTRODUÇÃO: Trachemys scripta elegans (Wied-Neuwied, 1839), é uma espécie de tartaruga de água doce, nativa da América do Norte, pertencente à subordem Cryptodira e à família Emydidae. Possui uma ampla distribuição geográfica devido à sua comercialização e adaptação a diversos habitats. Sua alimentação varia de acordo com o seu período de vida. Enquanto jovens, elas se alimentam principalmente de carne e quando adultas, de vegetais. No Brasil, a espécie é considerada invasora, e é comercializada ilegalmente como pet. Quando esses animais crescem, eles costumam ser agressivos e por esse motivo seus donos costumam abandoná-los em parques da cidade nos quais contém lagos que possivelmente estejam contaminados. Por isso, a caracterização elementar em amostras biológicas de organismos que vivem nestes ambientes possui grande importância para avaliar a concentração de elementos acumulados no animal, assim detectando possíveis contaminantes presentes nos corpos d’água que possam vir a interferir na saúde humana e qualidade ambiental. OBJETIVO: Identificar contaminantes presentes nos cascos de tartarugas Trachemys scripta elegans adultas, removidas dos parques da cidade de São Paulo. MATERIAIS E MÉTODOS: Foram utilizadas 10 fêmeas adultas, doadas pelo DEPAVE (Departamento de Parques e Áreas Verdes da Prefeitura de São Paulo), já eutanasiadas e congeladas no Centro Universitário São Camilo. Antes do início dos estudos foi obtido parecer CEUA (02/015). Para a realização da análise de contaminantes, feita através da Análise por Ativação com Nêutrons (AAN) no reator nuclear de pesquisas IEA-R1 do Instituto de Pesquisas Energéticas e Nucleares (IPEN), foi feita a separação do escudo epidérmico e do osso dos cascos das tartarugas com auxílio de bisturi e lupa. Todo material coletado foi colocado em envelopes, identificados e etiquetados. Alíquotas de 150 mg a 200 mg de cada amostra, e também, os materiais de referência foram inseridos em sacos de polipropileno, selados e enviados ao reator. As amostras irradiadas foram medidas em um detector e analisadas pelo software WinnerGamma. Após o cálculo das concentrações, foram interpretados os resultados e comparados com o da literatura. RESULTADOS: Foram identificados os elementos Br, Ca, Fe, K, Na e Zn. A maior concentração de Zn foi de 255± 8 mg/kg?¹ em uma amostra de escudo epidérmico e a menor foi de 64±2 mg/kg?¹ no osso. As concentrações de Zn variaram entre as amostras do escudo e osso, tendo sempre maiores valores no escudo. Ca e Na apresentaram comportamento oposto, tendo maiores concentrações no osso. O K foi detectado em apenas duas amostras do escudo. A concentração de Br foi semelhante entre as amostras de escudo epidérmico e osso e o mesmo ocorreu com o elemento Fe. CONCLUSÃO: Através da análise feita, foi possível identificar elementos em altas concentrações. Além disso, são necessários outros estudos com animais em ambientes controlados para relacionar essas concentrações com o que pode ser encontrado em seu habitat.

  

• IPEN-DOC 25993

  EL HAJJ, T.M.; SILVA, P.S.C. ; GANDOLLA, M.P.A.; DELBONI JUNIOR, H.. Surface treatments on ornamental rock plates to reduce radon and thoron exhalation rates. In: ENA WORKSHOP, 1st; EANNORM WORKSHOP, 9th, November 19-22, 2018, Katowice, Poland. Abstract... 2018.

  

• IPEN-DOC 25992

  REIS, S.L. ; MUCCILLO, E.N. . Influence of gallium-based additives on microstructure and ionic conductivity of doped-lanthanum gallate. In: CONFERENCE ON ELECTRONIC AND ADVANCED MATERIALS, January 17-19, 2018, Orlando, Florida, USA. Abstract... Westerville, OH, USA: The American Ceramic Society, 2018. p. 73-73.

  Abstract: Sr- and Mg-doped lanthanum gallate is a well known oxide-ion conductor with potential application in Solid Oxide Fuel Cells operating at intermediate temperatures (500-700oC). One of the main concerns on this solid electrolyte is related to impurity phases, frequently observed even in chemically synthesized powders, due to gallium loss during sintering. La0.9Sr0.1Ga0.8Mg0.2O3-d, LSGM, containing small amounts of Ga2O3 and Sr3Ga2O6 were prepared by solid state reaction, and the effects of the additives on microstructure and ionic conductivity were investigated after sintering at 1350oC. Gallium oxide addition promoted grain growth of LSGM and increased the fraction of the gallium-rich impurity phase. In contrast, strontium gallate addition favored reduction of the fraction of impurity phases. The intragrain conductivity of LSGM increases with gallium oxide addition, whereas strontium gallate improved both the intra- and the intergrain conductivities of LSGM.

  

• IPEN-DOC 25991

  PORFIRIO, T.; MUCCILLO, E.N. ; MARQUES, F.; MUCCILLO, R. . Samaria-doped ceria with impregnation of molten lithium/potassium carbonate for application as CO2 separation membranes. In: CONFERENCE ON ELECTRONIC AND ADVANCED MATERIALS, January 17-19, 2018, Orlando, Florida, USA. Abstract... Westerville, OH, USA: The American Ceramic Society, 2018. p. 36-36.

  Abstract: Composite membranes for carbon dioxide separation were obtained with vacuum infiltration of an eutectic mixture of potassium and lithium molten carbonates into a samaria-doped ceria (SDC) porous matrix at high temperature. Porous SDC were obtained by thermal removal of LiF sacrificial pore former. Scanning electron microscopy and scanning probe microscopy micrographs allowed for estimating pore volume and molten carbonate percolation through porous SDC. Impedance spectroscopy measurements at temperatures below and above the melting temperature of the carbonates show the contributions of oxide and carbonate ions to the total electrical conductivity of the ceramic membranes, which is dependent on the pore volume.

  

• IPEN-DOC 25990

  REIS, S.L. ; MUCCILLO, E.N. . Effects of dysprosium oxide on sintering behavior and electrical conductivity of samarium doped ceria. In: CONFERENCE ON ELECTRONIC AND ADVANCED MATERIALS, January 17-19, 2018, Orlando, Florida, USA. Abstract... Westerville, OH, USA: The American Ceramic Society, 2018. p. 35-35.

  Abstract: Solid electrolytes based on rare earth-doped cerium dioxide are of considerable interest for potential application in intermediate- temperature solid oxide fuel cells, IT-SOFC. Nevertheless, some constraints related to their sintering behavior along with improvement of the ionic conductivity are still object of investigation. In this work, dysprosium ion was chosen as a second additive/dopant, aiming to obtain a ceramic solid electrolyte with optimized ionic conductivity. Compounds of Sm0.2-xDyxCe0.8O1.9 with 0 % x % 0.2 were prepared by solid-state reaction, and the influence of the additive content on densification and ionic conductivity was analyzed by density, X-ray diffraction and impedance spectroscopy measurements. All compositions were found to exhibit cubic fluorite-type structure. The sintered solid electrolytes achieved densities higher than 92% of the theoretical value after sintering at 1500°C/3 h, and higher ionic conductivity than the Sm0.2Ce0.8O1.9 parent electrolyte.

  

• IPEN-DOC 25988

  REQUENA, MICHELLE B.; PIRES, LAYLA; PERMANA, ANDI D.; FREITAS, ANDERSON Z. de ; KURACHI, CRISTINA; SALVIO, ANA G.; DONNELLY, RYAN F.; BAGNATO, VANDERLEI S.. Dissolving microneedles with aminolevulinic acid for PDT: a pilot study in human skin. In: SÃO PAULO SCHOOL OF ADVANCED SCIENCE ON MODERN TOPICS IN BIOPHOTONICS, March 20-29, 2019, São Carlos, SP. Abstract... 2019. p. 67-68.

  Abstract: Photodynamic Therapy (PDT) is a therapeutic modality that has been applied mainly to skin cancer treatment. For topical PDT, the photosensitizer (PS) precursors are usually applied in a cream form. Aminolevulinic Acid (ALA) and its derivatives are the most common photosensitizer’s precursors used, allowing the Protoporphyrin IX (PpIX) accumulation. One of the challenges in topical PDT for skin cancer is to increase the cream permeation to improve the success rate and treat deeper lesions. Microneedles (MNs) are minimally invasive systems already used for intradermal vaccination, delivery of systemic drugs such as antibiotics or hormones. In this study, we prepared dissolving MNs using 5% ALA concentration and 20% of Gantrez AN-139 polymer. The patch has 361 pyramidal microneedles with 500 μm high. The tests of mechanic strength, dissolution, and stability of MNs were encouraging to perform this study. Three healthy volunteers received the MNs patches on the forearm, and optical coherence tomography (OCT) images were collected showing the induced microholes in the skin after the MN removal. We compared the superficial PpIX formation of the dissolving MNs and the standard cream at 20% concentration by a fluorescence spectroscopy system. The study showed that even in lower concentration, the MNs were able to produce a similar amount of PpIX compared to the cream in the same incubation time. The results were encouraging to perform an animal tumor model to support the understanding of the PDT.

  

• IPEN-DOC 25987

  SABINO, C.P.; RIBEIRO, M.S. ; BAPTISTA, M.S.; LINCOPAN, N.. Antimicrobial photodynamic therapy challenges microbial drug-resistance. In: SÃO PAULO SCHOOL OF ADVANCED SCIENCE ON MODERN TOPICS IN BIOPHOTONICS, March 20-29, 2019, São Carlos, SP. Abstract... 2019. p. 61-61.

  Abstract: Background: The rising challenge of microbial resistance to chemotherapy demands immediate implementation of global policies and therapeutic alternatives. Antimicrobial photodynamic therapy (APDT) combines the administration of a photosensitizer (PS) compound with low-intensity monochromatic light to induce photochemical reactions that yield high amounts of reactive oxygen species (ROS). Since some PS molecular frameworks can be selectively incorporated by pathogens and ROS react with virtually all biomolecules, APDT offers a powerful strategy to challenge microbial resistance of local infections. Methods: In this study we assayed the APDT efficacy, using methylene blue (MB) as PS and red light provided by LED, against planktonic suspensions of high-risk representative fungal and bacterial species. The species tested include A. baumannii (OXA-23 and 143), E. aerogenes (NDM-1), E. faecalis (VAN-B), E. faecium (VAN-A), E. coli (MCR-1, CTX-M8 and 15), K. pneumoniae (KPC-2, IMP-1, OXA-48), S. aureus (MRSA, VISA), P. aeruginosa (VIM-1, SPM-1, GES- 5), C. albicans and C. neoformans. For all species, we tested standard control strains compared to azole-resistant yeast, or bacteria resistant to nearly all commercially available antimicrobials, in attempt to observe any crossresistance in between APDT and standard chemotherapy. Results: More than 5log10 reduction was observed within less than a minute of illumination for non-capsulated bacteria and within less than 5 minutes for yeast and capsulated bacteria. Regardless of resistance phenotype MB-APDT presented species-specific dose-response kinetics suggesting that similar therapeutic protocols may bring successful outcomes in clinical practice. Conclusions: Our study proposes that MB-APDT can efficiently inactivate a broad-spectrum of drug-resistant microorganisms and impair drug-resistance genes selection and dissemination.

  

• IPEN-DOC 25986

  SALVADOR, F.F.S. ; FELINTO, M.C.F.C. ; FRANCISCO, L.H.C. ; BARBOSA, H.P.; BRITO, H.F.. Optical properties of Eu 3+ and Tb 3+ - doped tin dioxide nanoparticles prepared by coprecipitation method. In: SÃO PAULO SCHOOL OF ADVANCED SCIENCE ON MODERN TOPICS IN BIOPHOTONICS, March 20-29, 2019, São Carlos, SP. Abstract... 2019. p. 45-45.

  Abstract: Rare earth (RE) ion doped phosphors have attracted great interest during the past several decades due to their unique physical and chemical properties. RE ions can display many meaningful properties in optics, electronics, and magnetics, originating from f-f electronic transitions within the 4f shell. Doping of wide band gap of metaloxide semiconductors with RE proved to be a successful tool for tailoring their electrical, optical and microstructural properties. Tin dioxide combines high electrical conductivity with optical transparency. The luminescence of pure SnO2, observed in the UV and/ or visible region (350-550 nm) is generally correlated with the presence of crystalline defects, mainly oxygen vacancies, the most likely candidates for recombination centers in emission processes for SnO2 samples. In this work, the incorporation of the Tb3+ and Eu3+ - doped SnO2 nanoparticles were prepared by coprecipitation method. In semicontuctor nanocrystals, lattice distortions near the surface may produce distinct RE3+ environments, which may be enough to affect their band structure and to relax the dipole-forbidden rule. SnO2:Eu3+ presents the appropriate energetic configuration, which takes effect the luminescence in visible range. The ground state (7F0) and some of the metastable excited levels of Eu3+ ion (5D0, 5D1) are situated in the band gap of SnO2. It allows to observe a typical orange/red emissiom from the excited 5D0 to 7FJ (J=0-4) levels. SnO2: Tb3+ presents the transition 5D4→ 7F6 more intense than 5D4→7F5 and exhibit bluish emission in chromaticity diagram. The CIE parameters and CCT values were also varied and the emission color can be tuned from warm to cool light. In addition, this work opens the possibility to produce new functionalized nanoparticles with control of luminescent properties for photonic and biomedical applications.

  

• IPEN-DOC 25985

  SANTOS, CAROLINA M. dos ; FIGUEIREDO, ALINE M. de ; LEITE, RODRIGO C. ; CAMARGO, NATANE M. de; AFFONSO, REGINA . A new approach to obtain the catalytic site of human Angiotensin Converting Enzyme. In: EUROPEAN SYMPOSIUM ON BIOCHEMICAL ENGINEERING SCIENCES, 12th, September 9-12, 2018, Lisbon, Portugal. Abstract... Frankfurt am Main, Germany: European Society of Biochemical Engineering Sciences - ESBES, 2018.

  Abstract: Angiotensin-converting enzyme I (ACE) is a key part of the renin-angiotensin system whose main function is to regulate blood pressure. The sACE possesses two domains, N- C-, with catalytic sites which exhibit 60% sequence identity. These domains differ in terms of chloride-ion activation profiles, rates of peptide hydrolysis of angiotensin I, bradykinin, angiotensina (1-7), beta-amyloid peptide and sensitivities to various inhibitors. A more detailed analysis shows that these regions are composed of HEMGH and EAIGD sequences, which are the catalytic sites. Our question is: If the synthesis of catalytic sites with corrects structure and activity could be a good model per si to study new drugs. In our laboratory the catalytic site of the C-domain was obtained with correct structural conformation and with enzymatic activity. The objective this work is to obtain the Ala361 to Gli468 catalytic site, N-domain, in a structural conformation that resembles its native form. The 380 pb cDNA to catalytic site was cloned in the pE1 vector (kindly provided by Dr. David Wood), elastinlike-polyptide (ELP) tag sequence was linked with catalytic site, ELP~csACEn recombinant protein, this was expressed in bacteria with Terrificus broth with 0.1 mM IPTG for 20h. Harvested cells were resuspended in TE buffer, after sonication and centrifugation the pellet was resuspended the same buffer. The ELP~csACEn was precipitated with 0.8 M ammonium sulfate and the tag sequence was cleaved by pH change, pH 6.2. All steps were analyzed by SDS-PAGE, Dot and Western blotting. The catalytic site was synthesized from bacterial system with ELP sequence tag in soluble form. The purification process was done by ammonium sulfate precipitation and cleavage of the ELP sequence by changing to acidic pH. The characterization of catalytic site by SDS-PAGE shows that this is pure and Western blotting immunological assay confirmed the identity of the protein as csACEn. The strategy used to obtain the Ala361 to Gli468 catalytic site in soluble and pure form was successful. The next steps: we will continue with the Maldi-tof and structural conformation analyzes.

  

• IPEN-DOC 25984

  FUJIMOTO, T. ; MUCCILLO, E. . Preparation and characterization of solid electrolyte compounds consisting of doped lanthanum gallate and yttria stabilized zirconia. In: ECerS CONFERENCE, 16th, June 16-20, 2019, Turin, Italy. Abstract... Mons, Belgium: European Ceramic Society - ECerS, 2019. p. 740-740.

  

• IPEN-DOC 25982

  MAZZILLI, B.P. ; CAMPOS, M.P. ; NISTI, M.B. ; MADUAR, M.F. . Radiological implications of using phosphogypsum as building material: a case study of Brazil. In: ENA WORKSHOP, 1st; EANNORM WORKSHOP, 9th, November 19-22, 2018, Katowice, Poland. Abstract... ENA - European NORM Association, 2018. p. 80-80.

  

• IPEN-DOC 25981

  MADUAR, MARCELO F. ; MAZZILLI, BARBARA P. ; NISTI, MARCELO B. . Modelling of radiation doses arisen from the use of phosphogypsum-made bricks in construction. In: ENA WORKSHOP, 1st; EANNORM WORKSHOP, 9th, November 19-22, 2018, Katowice, Poland. Abstract... ENA - European NORM Association, 2018. p. 75-75.

  

• IPEN-DOC 25980

  MADUAR, MARCELO F. ; MIRANDA JUNIOR, PEDRO. Continuous wavelet transform in the analysis of gamma-ray spectra with NORM. In: ENA WORKSHOP, 1st; EANNORM WORKSHOP, 9th, November 19-22, 2018, Katowice, Poland. Abstract... ENA - European NORM Association, 2018. p. 86-86.

  

• IPEN-DOC 25971

  SILVA, CAMILA R. ; CONTATORI, CAROLINA G. de S. ; PEREIRA, SAULO de T. ; RIBEIRO, MARTHA S. . Photobiomodulation can delay tumor progression in breast cancer bearing-mice. In: LATIN AMERICA OPTICS AND PHOTONICS CONFERENCE, November 12-15, 2018, Lima, Peru. Resumo expandido... Washington, DC, USA: OSA, 2018.

  Abstract: Cancer is a worldwide health problem and new therapeutic strategies are necessary. Photobiomodulation is a noninvasive and cost-effective therapy, but its use in cancer cells is still controversial. In this study, we explore the effects of PBM on breast tumor bearing-mice.

  

• IPEN-DOC 25970

  CABRAL, F.V. ; PELEGRINO, M.T.; SEABRA, A.B.; RIBEIRO, M.S. . Could NO-releasing chitosan nanoparticles improve photodynamic therapy on cutaneous leishmaniasis?. In: LATIN AMERICA OPTICS AND PHOTONICS CONFERENCE, November 12-15, 2018, Lima, Peru. Resumo expandido... Washington, DC, USA: OSA, 2018.

  Abstract: Photodynamic inactivation (PDI) and NO-releasing chitosan nanoparticles (CSNPs) were associated to treat cutaneous leishmaniasis in mice to verify synergism between therapies. Parasite burden, lesion size and hyperalgesia were analyzed. CSNPs were not able to improve PDI.

  

• IPEN-DOC 25946

  YOUNG, N.C.; MOSCA, R.C. ; ZEITUNI, C.A. ; ARANY, P.R.. Smart dental fillings with ruthenium nanoparticles-enhanced photobiomodulation therapy for pulp-dentin regeneration. In: SOCIETY FOR BIOMATERIALS ANNUAL MEETING AND EXPOSITION, 42nd., April 3-6, 2019, Seattle, Washington, USA. Abstract... New Jersey, USA: Society For Biomaterials, 2019.

  

• IPEN-DOC 25945

  LIMA, CASSIO ; CORREA, LUCIANA; BYRNE, HUGH; ZEZELL, DENISE M. . FTIR spectroscopy: a valuable tool to diagnose cutaneous tumors. In: NEXT FRONTIERS TO CURE CANCER, 10-12 de maio, 2018, São Paulo, SP. Abstract... São Paulo: A.C.Camargo Cancer Center, 2018.

  Abstract: Biological molecular bonds with an electric dipole moment that can change by atomic displacement due to natural vibrations are infrared active and therefore are quantitatively measured by Fourier transform Infrared Spectroscopy (FTIR), which is a rapid and label-free analytical tool that has been used to study the chemical interactions between biomolecules. The potential of FTIR spectroscopy as a diagnostic tool to discriminate cancerous from healthy tissue in a non-subjective manner has been well demonstrated. However, translation into clinical practice has been relatively slow, mainly due to the expensive and fragile infrared substrates required to perform the measurements. Thus, this study aims to demonstrate the ability of FTIR microspectroscopy to discriminate healthy skin from hyperplastic, papilloma and squamous cell carcinoma using standard H&E stained samples placed on glass slides. After approval of the ethics committee for research on animals (Comite de Etica no Uso de Animais, CEUA) of Instituto de Pesquisas Energéticas e Nucleares (IPEN) (project no. 164/15-CEUA-IPEN/SP), cutaneous neoplastic lesions were chemically-induced in the back of Swiss mice using a well- -stablished two-stage carcinogenesis protocol [1]. Healthy tissue was collected from animals non-exposed to chemicals and different diseased stages (hyperplastic epidermis, papillomatous lesions and squamous cell carcinoma (SCC)) were obtained by varying the exposure time of the animals to carcinogenenic factors.Tissue sections of 5 μm thickness were obtained from formalin-fixed paraffin-embedded (FFPE), hematoxylin & eosin stained and placed on glass slides. FTIR images were acquired in transmission mode over the spectral range 3000-3800 cm-1 with a pixel size of 6.25 × 6.25 μm at a spectral resolution of 4 cm-1. Spectral data were vector normalised and subjected to smoothing using Savitzky–Golay filtering with a polynomial of second order in an eleven point window. Principal components analysis (PCA) was applied and the PC scores were used as input data for linear discriminant analysis (PC-LDA) in a binary classification test. The groups were pairwise compared and the method was validated by leave-one-out cross-validation (LOOCV). All pre-processing and spectral analysis were performed on Matlab® R2017. Considering the sensitivity as the proportion of spectra collected from healthy tissue correctly identified in the healthy group and specificity as the proportion of spectra measured from neoplastic skin correctly associated to neoplastic group, the performance of classification obtained by PC-LDA was calculated for each pairwise comparison: Healthy × Hyperplastic, Healthy × Papilloma, Healthy × SCC, Hyperplastic × Papilloma, Hyperplastic × SCC, Papilloma × SCC. Sensitivity and specificity values over 90% were obtained for all groups compared, indicating that the information retained by bands peaking at 3000-3700 cm-1 in the infrared spectra — associated with the stretching vibrational modes of N-H, O-H and C-H chemical bonds on biological tissue — can discriminate normal and malignant tissue using H&E stained samples placed on glass slides. Thus, FTIR spectroscopy associated to PC-LDA as a binary classification test may be used as a complementary tool to help physicians to detect early stages of skin cancer, as well as to differentiate different types of cutaneous tumors.

  

• IPEN-DOC 25941

  SANTANA, L.V. ; COTRIM, M.E.B. ; SISTI, C. ; SILVA, C.M. ; SAID, D.S. ; PIRES, M.A.F. . Determination of the minimum sample mass of U3Si2 to be used as candidate reference material for chemical analyses of total uranium and total silicide. In: INTERNATIONAL SYMPOSIUM ON NATURALLY OCCURRING RADIOACTIVE MATERIAL, 8th, October 18-21, 2016, Rio de Janeiro, RJ. Proceedings... Vienna, Austria: IAEA, 2018. p. 356-360. (Proceedings Series IAEA).

  Abstract: To guarantee the reliability and comparability of analytical data, the use of reference materials is essential. Uranium intermetallic compounds, in particular U3Si2, have been the preferred fuel materials for high flux research reactors. A method for the quantitative determination of the minimum representative sample mass of a candidate for reference material for determination of total uranium and silicide is described and illustrated in this paper. The analytical method used for determination of total uranium was the high precision potentiometric titration method of Davies and Gray, while total silicide was determined gravimetrically. The study was conducted according to ISO Guide 35. A preliminary test for homogeneity can be performed after homogenization as an integral part of the candidate reference material preparation.

  

• IPEN-DOC 25940

  ALMEIDA, H.C.; NASCIMENTO, T.B.S.; TADDEI, M.H.T.; MAZZILLI, B.P. . Comparison of 210Pb and 210Po activity concentrations for sediment dating. In: INTERNATIONAL SYMPOSIUM ON NATURALLY OCCURRING RADIOACTIVE MATERIAL, 8th, October 18-21, 2016, Rio de Janeiro, RJ. Proceedings... Vienna, Austria: IAEA, 2018. p. 213-217. (Proceedings Series IAEA).

  Abstract: Records stored in natural archives, such as those for lake sediments, are used in environmental programmes for the assessment of changing erosion rates in a catchment arising from disturbances, and to monitor pollution by heavy metals and other contaminants. Accurate sediment chronologies are important to interpret those practices. One of the most important methods for dating recent sediments is through 210Pb. This radionuclide occurs naturally as one of the 238U decay series. It is widely distributed on Earth owing to its decay from radium in the ground or from radon that emanates to the atmosphere. The 210Pb is deposited as particulates and falls into lakes where it is scavenged from the water column and deposited in the basins. The elevated 210Pb concentrations are measured using the gamma spectrometry technique. However, this technique has a low sensitivity and small values are difficult to detect or require a long measurement time. The determination of 210Po (a decay product of 210Pb) using alpha spectrometry is more sensitive and rapid. The aim of this paper is to compare the activity concentrations of the two radionuclides in lake sediment samples to evaluate the use of 210Po in the dating of sediments with low levels of 210Pb.

  

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