GONÇALVES, KARINA de O.COURROL, LILIA C.CORAZZA, FULVIOVIEIRA, DANIEL P.2019-10-162019-10-16GONÇALVES, KARINA de O.; COURROL, LILIA C.; CORAZZA, FULVIO; VIEIRA, DANIEL P. Silver and silver-iron nanoparticles synthesized by photoreduction for applications in cancer therapy. In: SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE, October 7-9, 2019, São Paulo, SP. <b>Proceedings...</b> DOI: <a href="https://dx.doi.org/10.1109/SBFoton-IOPC.2019.8910264">10.1109/SBFoton-IOPC.2019.8910264</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/30284.http://repositorio.ipen.br/handle/123456789/30284Metal nanoparticles have been extensively studied for various purposes including therapeutic applications for cancer. In this study, nanoparticles of silver and silver-iron with aminolevulinic acid (ALA) were synthesized using (ALA:AgNPs and ALA:AgFeNPs) the photoreduction method with a 300 W xenon lamp, characterized by UV/vis absorption, zeta potential, x-rays diffraction, FTIR and transmission electron microscopy. The sizes obtained were ~ 23 nm for silver and ~ 12 nm for iron. Cytotoxicity assays were performed on breast tumor cells (MCF-7) and prostate cancer cells (LNCaP). The results obtained showed that it was possible to synthesize silver and silver-iron nanoparticles by the photoreduction method, and to functionalize their surfaces with ALA, which was delivered to the cells and converted to protoporphyrin IX (PpIX).openAccesssilverironnanoparticlesphotochemistryreductionneoplasmsnuclear medicinetherapyTexto completo de evento10.1109/SBFoton-IOPC.2019.89102640000-0002-0007-534Xhttps://orcid.org/0000-0002-0007-534X