VIEIRA, DANIEL P.2022-03-252022-03-25VIEIRA, DANIEL P. Three-dimensional cellular culture system for testing of biological effects of radiations in tumoral and non-tumoral models. In: CONGRESS OF THE INTERNATIONAL UNION FOR PURE APPLIED BIOPHYSICS, 20th; ANNUAL MEETING OF THE BRAZILIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 50th; CONGRESS OF BRAZILIAN BIOPHYSICS SOCIETY, 45th; BRAZILIAN SOCIETY ON NUCLEAR BIOSCIENCES CONGRESS, 13th, October 4-8, 2021, São Paulo, SP. <b>Abstract...</b> São Paulo, SP: Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq), 2021. p. 89-89. Disponível em: http://repositorio.ipen.br/handle/123456789/32864.http://repositorio.ipen.br/handle/123456789/32864In vitro cell cultures are a well-known controlled test system used to analyze tumor physiologic responses upon negative stimuli. Updated techniques, us-ing three-dimensional organization of cells in cultures, are being increasingly used to this purpose. Research organizations and industry are striving to pro-duce in vitro tumor surrogates that could be better test systems to antitumor agents as new compounds or to study radiation effects on cancers. The presentation will show some techniques currently used to build and maintain these specific cell cultures, and how experiments are evolving towards the production of tumoroids, or tumoral organoids, which will include various cell types and additive manufacturing.89-89openAccesscell culturesthree-dimensional calculationstumor cellsradiationsResumo de eventos científicos0000-0002-0007-534Xhttps://orcid.org/0000-0002-0007-534X