SEPULVEDA, ANDERSON F.FRANCO, MARGARETHYOKAICHIYA, FABIANOARAUJO, DANIELE de2022-03-252022-03-25SEPULVEDA, ANDERSON F.; FRANCO, MARGARETH; YOKAICHIYA, FABIANO; ARAUJO, DANIELE de. POLYana: a new software for rheological study of polymeric colloidal materials. In: CONGRESS OF THE INTERNATIONAL UNION FOR PURE APPLIED BIOPHYSICS, 20th; ANNUAL MEETING OF THE BRAZILIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 50th; CONGRESS OF BRAZILIAN BIOPHYSICS SOCIETY, 45th; BRAZILIAN SOCIETY ON NUCLEAR BIOSCIENCES CONGRESS, 13th, October 4-8, 2021, São Paulo, SP. <b>Abstract...</b> São Paulo, SP: Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq), 2021. p. 374-374. Disponível em: http://repositorio.ipen.br/handle/123456789/32874.http://repositorio.ipen.br/handle/123456789/32874POLYAna is a new executable software developed by SISLIBIO group for rheological analysis of hydrogel and organogel systems and other colloidal materials (nanoparticles and micelles). The software development aims to facilitate the analysis of rheology data associated to both temperature- and frequency-dependent analysis, viscosity and curve flow profiles. The software development aims to facilitate the analysis of rheology data associated to both temperature- and frequency-dependent analysis, viscosity and curve flow profiles. From raw data, several models are applied like power-law model for frequency response and curve flow, Boltzmann law to calculate gelation temperature and viscosity response under temperature, Maxwell model to study interchain relationships in addition to other models such as Bingham model, Cross model, and Herschel-Bulkley are also available. POLYana outputs calculates rheological parameters like consistency, adhesion, hysteresis, flow index, G’/G’’ ratio. To validate results obtained from POLYana, same data were analyzed by applying other programs and same mathematical models. In this sense, rheological analysis of Poloxamer 407 in water solution (15 %) were performed: from temperature-dependent G’ and G’’ analysis were obtained gelation temperature of 45.46 ± 0.02 °C, η_0 = 0.08 ± 0.03 mPa*s, η_max = (32.44 ± 0.17) mPa*s and dη/dT = (1.27 ± 0.02) mPa*s/°C by fitting Boltzmann law (R2 = 0.998), which are similar to results obtained by others softwares and found in literature. From temperature-dependent G’ and G’’ analysis, it gets adhesion value of (1647.15 ± 18.01) mPa*sn calculated from power-law model (R2 = 0.869), also similar to PRISM results. Also, other Poloxamer concentrations and hydrogels types have been evaluated, showing close numbers to that previously reported. In order to stablish structural relationships, one of POLYana tools is also to analyze small-angle neutron scattering (SANS) and develop Monte Carlo simulation for SANS and rheological analysis, simultaneously.374-374openAccessprogrammingdata analysisrheologymicellar systemscolloidsPOLYanaResumo de eventos científicos