ZAMBONI, C.B.GIOVANNI, D.N.S.ALMEIDA, M.R.TODO, A.S.SABARA, F.RODRIGUES JUNIOR, O.2024-03-072024-03-072023ZAMBONI, C.B.; GIOVANNI, D.N.S.; ALMEIDA, M.R.; TODO, A.S.; SABARA, F.; RODRIGUES JUNIOR, O. X- ray experimental set-up for in-vitro nail test. <b>Brazilian Journal of Radiation Sciences</b>, v. 11, n. 1A, p. 1-10, 2023. DOI: <a href="https://dx.doi.org/10.15392/2319-0612.2023.2207">10.15392/2319-0612.2023.2207</a>. Disponível em: https://repositorio.ipen.br/handle/123456789/47902.2319-0612https://repositorio.ipen.br/handle/123456789/47902In this investigation, the elements Ca and S were evaluated in a single nail clipping using compact and portable X-ray spectrometer model X-123 SDD with Ag target. Experimental conditions for current, voltage and excitation time were investigated. These analyses can be useful for a variety of applications, including nutritional and medical diagnosis, such as, the evaluation of bone dysfunctions by measurement of Ca (bone decalcification) and S for nutrition evaluations (collagen production). This analysis offers some benefits comparatively to blood and serum analyses, such as, non-invasive collection, fast analyses (minutes) and low cost. In addition, nail clippings are simple to obtain, easy to store, and easy to transport. This pilot study show a positive expectation for clinical application using in-vitro nail test.1-10openAccessx-ray fluorescence analysisnailsionsclinical trialskeratindiagnostic techniquescalciumsulfurArtigo de periódico1A1110.15392/2319-0612.2023.2207https://orcid.org/0000-0001-7766-2692https://orcid.org/0000-0002-6704-1910Sem PercentilSem Percentil CiteScore