VERCIK, LUCI C. de O.VERCIK, ANDRESBRESSIANI, JOSE C.2014-07-152014-07-302014-07-152014-07-302009VERCIK, LUCI C. de O.; VERCIK, ANDRES; BRESSIANI, JOSE C. Development of gelatin/HA membranes. <b>Key Engineering Materials</b>, v. 396-398, p. 421-424, 2009. DOI: <a href="https://dx.doi.org/10.4028/www.scientific.net/KEM.396-398.421">10.4028/www.scientific.net/KEM.396-398.421</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/4880.1013-9826http://repositorio.ipen.br/handle/123456789/4880The aim of this work is to develop membranes of gelatin/hydorxyapatite composite for using as mechanical barrier. Membranes with 4% of gelatin and 0.5-3% of hydroxyapatite were studied. The composite was obtained by heterogeneous co-precipitation method. X-ray diffractometry showed the formation of a pure phase of hydroxyapatite with excellent crystallinity. Using atomic force microscopy, the distribution of crystals of hydroxyapatite in the gelatin matrix was observed, with nanoparticles of about 50-100nm in a homogeneous mixture. After crosslinking process with glutaraldehyde at different concentrations (0.5, 1, 1.5 and 2%), a significant decrease of the swelling behavior was observed due to the increase of the amount of triple helix in the samples, which increases their stability in aqueous solution.421-424openAccessmembranesgelatinapatitesanimal tissuesbiological regenerationatomic force microscopycross-linkingswellingArtigo de periódico396-39810.4028/www.scientific.net/KEM.396-398.421