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  • Artigo IPEN-doc 24129
    A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotron
    2017 - LAPOLLI, ANDRE L.; BARCELLOS, HENRIQUE; MATSUDA, HYLTON; SUMIYA, LUIZ C. do A.; JUNQUEIRA, FERNANDO de C.
    Since 2001 the Nuclear and Energy Research Institute (IPEN/CNEN-SP, Brazil) has produced about 2.5 mCi/mAh of 123I weekly using a manual irradiation system fully developed by its researchers. Ultrapure 123I has been produced and distributed to hospitals and clinics where several diagnostic imaging procedures are done for thyroid, brain and cardiovascular functions. Due to the short half-life and emission of low-energy photons, this radioisotope becomes suitable for diagnosis in children. Currently IPEN researchers are involved in the development of a new fully automated irradiation system dedicated to 123I routine production employing enriched xenon gas (124Xe) as the target material. This new system consists of a target port, a water and a helium cooling system, a cryogenic system, an electric power system, a control and process monitoring unit composed of a supervisory software connected to a Programmable Logic Controller (PLC) via personal computer. In this new concept, there is no need for human interference during radioisotope production, reducing the possibility of eventual failures or incidents involving radioactive material. In this way, with this new system, a specific yield of approximately 3.5 mCi/mAh per irradiation is expected and this will meet a large part of the national demand for this important radioisotope. In the present work will be presented all the technical and constructive aspects of this new system as well as the results obtained in the irradiation of tests.