GUSTAVO HENRIQUE COSTAVARCA
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Artigo IPEN-doc 25125 Current methods applied to biomaterials – characterization approaches, safety assessment and biological international standards2018 - OLIVEIRA, JUSTINE P.R.; MELENDEZ-ORTIZ, H.I.; BUCIO, EMILIO; ALVES, PATRICIA T.; LIMA, MAYARA I.S.; GOULART, LUIZ R.; MATHOR, MONICA B.; VARCA, GUSTAVO H.C.; LUGAO, ADEMAR B.Safety and biocompatibility assessment of biomaterials are themes of constant concern as advanced materials enter the market as well as products manufactured by new techniques emerge. Within this context, this review provides an up-to-date approach on current methods for the characterization and safety assessment of biomaterials and biomedical devices from a physical-chemical to a biological perspective, including a description of the alternative methods in accordance with current and established international standards.