NATHALIA FONSECA BOIANI
11 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 11
Artigo IPEN-doc 29329 Toxicidade aguda e avaliação de riscos ecológicos de fármacos pertencentes a diferentes classes detectados em ambientes aquáticos2021 - TOMINAGA, F.K.; BOIANI, N.F.; GARCIA, V.S.G.; SILVA, T.T.; LEO, P.; BORRELY, S.I.Artigo IPEN-doc 29328 Avaliação da toxicidade da mistura de fármacos submetidos a irradiação por feixe de elétrons2021 - BOIANI, N.F.; SILVA, T.T.; TOMINAGA, F.K.; GARCIA, V.S.G.; BORRELY, S.I.Artigo IPEN-doc 29145 Toxicity removal of pharmaceuticals mixtures through electron beam irradiation2022 - BOIANI, N.F.; TOMINAGA, F.K.; BORRELY, S.I.Contamination of the aquatic environment by pharmaceuticals is becoming a global phenomenon of growing concern. Pharmaceuticals are partially metabolized, resulting in the excretion and release of residual into sewage, unaltered or metabolites. The wastewater treatment plants are not designed to eliminate these compounds, leading the residues into the aquatic environment. Besides, pharmaceuticals are not detected individually but as a complex mixture. Advanced oxidative processes have been applied as an alternative or complement to conventional sewage treatment processes, aiming the degradation and removal of toxic pollutants. The objective of this study was to evaluate the toxicity removal of mixtures of pharmaceuticals subjected to electron beam treatment. The aqueous solutions of each pharmaceutical were diluted in ultra-pure water and prepared in three pharmaceuticals combinations: Propranolol + Fluoxetine + Sulfadiazine; Propranolol + Fluoxetine + Diclofenac; Acetylsalicylic acid + Fluoxetine + Metformin). Electron Beam Accelerator was applied for the irradiations and the absorbed doses were 2.5-5.0 kGy. Acute toxicity tests with Daphnia similis were performed to evaluate the toxicity, before and after irradiation.. The data analyzed showed toxicity removal efficiency around 80% for the mixture of Propranolol, Fluoxetine and Diclofenac; 75% for the mixture of Propranolol, Fluoxetine and Sulfadiazine; and 30% for the mixture of Acetylsalicylic acid, Fluoxetine and Metformin. According to the literature, this is a viable technology for the removal of toxicity from pharmaceuticals, and the results demonstrated the potential of electron beam irradiation in reducing the toxicity of pharmaceutical from different classes.Resumo IPEN-doc 28652 Avaliação da toxicidade de surfactantes não iônico e aniônico submetidos a tratamento por feixe de elétrons2021 - GARCIA, VANESSA S.G.; TOMINAGA, FLAVIO K.; BOIANI, NATHALIA F.; SILVA, THALITA T.; ROSA, JORGE M.; BORRELY, SUELI I.Artigo IPEN-doc 27915 Electron beam irradiation of combined pharmaceuticals2021 - BOIANI, NATHALIA F.; GARCIA, VANESSA S.G.; BORRELY, SUELI I.There are serious evidences that justify the search for treatment technologies or processes combination for the improvement of decomposition for dozens of pharmaceuticals in wastewaters. Electron beam irradiation may play an important role in this scenario and relatively low doses have been reported for such purposes. The aim of the present study was to evaluate the toxic response of the crustacean Daphnia similis exposed to individual and combined pharmaceuticals, before and after electron beam irradiation treatment. Several experimental trials of an acute immobilization test were performed with a mixture of pharmaceuticals composed of fluoxetine hydrochloride (Prozac®), and propranolol. Single pharmaceuticals were first tested separately. Toxicity of binary mixture was then assessed using five concentrations and five percentages of each substance in the mixture (0, 25, 50, 75, and 100%). Acute EC50% values ranged from 5.0 to 7.4 for fluoxetine and from 11.3 to 13.7 for propranolol. In mixture, values ranged from 6.4 to 9.8. Fluoxetine was more toxic than propranolol for D.similis. The different pharmaceuticals concentrations employed in a mixture showed no difference in toxicity values. When electron beam irradiation was applied, approximately 80% of acute effects were reduced at 5 kGy, and the mixture containing a higher percentage of fluoxetine, also showed a greater reduction of toxicity.Artigo IPEN-doc 25766 Electron beam irradiation of textile effluents and non-ionic ethoxylated surfactant for toxicity and color removal2019 - BORRELY, S.I.; SILVA, L.G.A.; DEL SOLE, S.V.; GARCIA, V.S.G.; BOIANI, N.F.; ROSA, J.M.Textile industry has an expressive scenario in the world economy and Brazil is the 5th in the textile production. By 2015, Brazilian textile production represented US $ 39.3 billion, accounting for more than 1.8 million tons of fabric. The effluents from textile industry are highlighted by quantity of wastewater discharged and variety of substances (dyes, bleaching agents, surfactants, salts, acids, among others). Such compounds often prove to be toxic to aquatic biota. This present study aims to assess toxicity of whole effluents, before and after irradiation (by electron beam accelerator, EBI). In addition, the reduction of the effluent color after irradiation is also very important. Daphnia similis and Vibrio fischeri were the biological systems applied for toxicity evaluations. Previous results demonstrated the surfactant as the main toxic compound, in the untreated and irradiated forms, EC 50 = 0.44 ppm ± 0.02 (untreated); EC 50 = 0.46 % ± 0.07 (irradiated). The irradiation was effective for reducing color of the effluent, starting from 0.5 kGy. EB irradiation may be proposed as an alternative treatment for the final effluent from textile processing, mainly for reuse purposes.Resumo IPEN-doc 25529 Avaliação da toxicidade do umectante não iônico e do corante reativo RED 239 submetidos à irradiação por feixe de elétrons2018 - GARCIA, VANESSA S.G.; ROSA, JORGE M.; PEREIRA, MARIA da C.C.; BOIANI, NATHALIA F.; BORRELY, SUELI I.Resumo IPEN-doc 25526 Toxicidade do Propranolol (comercial versus manipulado), e de sua mistura com o cloridrato de fluoxetina, quando tratado por radiação ionizante2018 - BOIANI, NATHALIA F.; GARCIA, VANESSA S.G.; TOMINAGA, FLAVIO K.; BORRELY, SUELI I.Artigo IPEN-doc 25525 Tratamento de efluentes provenientes da indústria curtidora, empregando acelerador de elétrons2018 - SOUZA, ANDERSON L. de; BOIANI, NATHALIA F.; BORRELY, SUELI I.A indústria produtora de couros (também conhecida como curtume) coloca o país entre os maiores produtores do setor. O Brasil tem o maior rebanho comercial do mundo, exporta mais de 2 bilhões de dólares ao ano para 80 países e emprega mais de 40 mil pessoas. A indústria curtidora brasileira busca, estação após estação, produtos cada vez mais eficientes e ligados à sustentabilidade para os mais exigentes mercados nacionais e internacionais. A produção industrial mais limpa vem induzindo o desenvolvimento de tecnologias que permitam otimizar o uso das matérias primas, além da água. No que concerne ao efluente, composto de várias substâncias, como: óleos (animal, mineral, vegetal e sintético), gorduras, proteínas, corantes, agentes curtentes (cromo, titânio e tanino vegetal), resinas, amaciantes, depilantes (sulfeto de sódio), ainda é uma limitação que pode ser adequada com uso da tecnologia. Técnicas modernas como: separação por troca iônica, eletrodiálise, ultrafiltração, osmose reversa têm sido aplicadas para tratamento de efluentes industriais. Outras como o Processo de Oxidação Avançada, POA, utilizando aceleradores de feixe de elétrons. O efluente bruto foi irradiado com doses de 20 kGy, 30 kGy, 40 kGy e 50 kGy. A eficiência deste processo foi avaliada pela caracterização da matéria orgânica (DBO e DQO), e ensaio de toxicidade aguda com o microcrustáceo Daphnia similis. A radiação ionizante mostrou-se eficiente na degradação da matéria orgânica e na redução da toxicidade dos efluentes em estudo.Resumo IPEN-doc 23915 Efeito da irradiação com feixe de elétrons na degradação e toxicidade de fármacos em solução aquosa: cloridrato de fluoxetina, diclofenaco de sódio e mistura de ambos2016 - TOMINAGA, F.K.; BOIANI, N.F.; SOLE, S.V.D.; BORRELY, S.I.