SABRINA METAIRON
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Artigo IPEN-doc 26305 Uso de mini-espectrômetro de fluorescência de raios-x como alternativa para prática clínica de dialisados2019 - SOUZA, CATARINA S.; ZAMBONI, CIBELE B.; SILVA, DALTON G.N. da; METAIRON, SABRINAO objetivo do presente estudo foi avaliar a performance da técnica de Fluorescência de Raios-X por Dispersão de Energia (FRX-DE) para análise de íons, de relevância clínica (Ca, Cl, K, Fe), em sangue total de pacientes com insuficiência renal crônica (IRC) submetidos a tratamento dialítico. Com os dados do presente foi possível elaborar uma discussão sobre as vantagens e limitações do uso deste procedimento para a realização desses exames bioquímicos em Centros de Hemólise. Durante a investigação as concentrações obtidas para Ca, Cl, K e Fe levaram a resultados que corroboram com o quadro clínico obtido pelas análises convencionais.Artigo IPEN-doc 26266 Correlation analysis of inorganic elements in whole blood of GRMD dogs using INAA2019 - METAIRON, SABRINA; ZAMBONI, CIBELE B.; SILVA, DALTON G.N. daInstrumental neutron activation analysis technique (INAA) has been used to determine Br, Ca, Cl, Cr, Fe, K, Mg, Na, P and S concentrations in whole blood of GRMD dogs’ samples from control, carrier and affected dogs (treated and untreated). The GRMD dogs are relevant as an experimental model for Duchenne Muscular Dystrophy (DMD), which is the most severe and prevalent type of muscular dystrophy. Muscle weakness, premature death and instability of the membrane that involves the muscle fibers - causing functional/structural abnormalities and cell death - are main characteristics of this genetic disease. To show in more details the alterations that this disease may cause in whole blood, correlations matrixes were generated for control, carried and affected groups permitting a comparison between them. The results emphasize physiologic differences for K and Mg and suggest that Br results are altered, emphasizing a constant monitoring need. Other than that, these results may help the researchers to evaluate the efficiency of new treatments and to compare the advantages of different treatment approaches before performing tests in patients with muscular dystrophy.Artigo IPEN-doc 26145 Progress and trends for radiation applications in clinical practice2019 - ZAMBONI, CIBELE B.; METAIRON, SABRINA; MEDEIROS, JOSE A.G. de; SILVA, DALTON G.N. da; TASSO, ORION G.In this study, we intend to optimize the use of equipment based on the X-Ray Fluorescence technology to perform ions dosage in body fluids. This procedure can be an efficient alternative for clinical diagnosis, mainly in underserved regions of Brazil with the deficit of medical care in the hospitals. In addition, this procedure has potential use when the biological material is scarce, case of the pediatric practice in newborns and premature infants (blood collection is the main cause of transfusions) as well as in Hemodialysis units which requires several biochemical tests (before and after dialysis).Artigo IPEN-doc 21226 Differences in iron concentration in whole blood of animal models using NAA2014 - BAHOVSCHI, V.; ZAMBONI, C.B.; LOPES SILVA, L.F.F.; METAIRON, S.; MEDEIROS, I.M.M.A.Artigo IPEN-doc 21225 Determination of inorganic elements in blood of mice immunized with Bothrops snake venom using XRF and NAA2014 - LOPES da SILVA, L.F.F.; ZAMBONI, C.B.; BAHOVSCHI, V.; METAIRON, S.; SUZUKI, M.F.; SANT'ANNA, O.A.; RIZZUTTO, M.A.Artigo IPEN-doc 20780 Investigation of Ca and Mg in blood of dystrophic animal model using NAA2013 - METAIRON, SABRINA; ZAMBONI, CIBELE B.; SUZUKI, MIRIAM F.; BUENO JUNIOR, C.R.; ANDRADE, T.O.; LANDINI, V.; CANGUSSU, E.B.; CAETANO, H.V.A.; ZATZ, CAETANO M.Artigo IPEN-doc 20766 The use of portable X-ray fluorescence spectrometry (PXRFS) for clinical practices2013 - ZAMBONI, C.B.; METAIRON, SABRINA; RIZZUTTO, MARCIA de A.; SANTOS, SUENE B. dosArtigo IPEN-doc 18865 Comparison of reference values in whole blood of DMDsup(mdx)/J and C57BL/6J mice using neutron activation analysis2010 - METAIRON, S.; ZAMBONI, C.B.; SUZUKI, M.F.; JUNIOR, C.R.B.; SANT'ANNA, O.A.Artigo IPEN-doc 19452 Analysis of inorganic elements in biological samples of C57BL/6J mouse strain INAA2013 - METAIRON, SABRINA; ZAMBONI, CIBELE B.; SUZUKI, MIRIAM F.; KOVACS, LUCIANA; BUENO JUNIOR, CARLOS R.Artigo IPEN-doc 19139 Investigation of saliva of patients with periodontal disease using NAA2012 - ZAMBONI, C.B.; METAIRON, S.; MEDEIROS, I.M.M.A.; LEWGOY, H.R.