BIANCA DA SILVA SUFI
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Artigo IPEN-doc 24377 Nutraceutical compound increases collagen, elastin and hyaluronic acid synthesis2017 - SCHALKA, SERGIO; MAGALHAES, WAGNER V.; CAZERTA, CAMILA; SHITARAC, DANIELLE; SUFI, BIANCA da S.; QUADROS, ANANDAIntroduction: The use of nutraceutical products in order to attenuate signs of skin aging has been proposed in the literature. The stimulus to the synthesis of substances that support the dermis is one of the mechanisms linked to this effect. Objective: To evaluate the effectiveness of a nutraceutical compound containing lutein, lycopene, vitamin C and manganese for the synthesis of collagen, elastin and hyaluronic acid. Methods: An in vitro study was carried out based on the culture of human fibroblasts treated with the investigated product in different non-cytotoxic concentrations. The quantification of the elastin and collagen was performed with the assistance of spectrophotometric measurements. Hyaluronic acid was measure using a immunoenzymatic method. Results: Cell cultures treated with the different concentrations of the product showed a significantly higher amount of synthesized collagen, elastin and hyaluronic acid as compared to the untreated culture (p <0.05). Conclusions: The use of the nutraceutical compound containing lycopene, vitamin C, lutein and manganese has shown in vitro efficacy for stimulating the synthesis of collagen, elastin and hyaluronic acid, components that are crucial for providing the dermis’ supporting structure, being responsible for the skin’s firmness and elasticityArtigo IPEN-doc 19400 Development and construction of a specific chamber for phototoxicity test2013 - SUFI, BIANCA S.; ESTEVES PEDRO, NATALIA M.; LOPES, PATRICIA S.; KANEKO, TELMA M.; MATHOR, MONICA B.Artigo IPEN-doc 19716 Uso de métodos alternativos na toxicidade in vitro de óleos essenciais da Mata Atlântica2013 - ESTEVES PEDRO, NATALIA M.; LOPES, PATRICIA S.; SUFI, BIANCA da S.; RODAS, ANDREA C.D.; MATHOR, MONICA B.; HIGA, OLGA Z.; VIEIRA, DANIEL P.; OKAZAKI, KAYO; MORENO, PAULO R.H.; BABY, ANDRE R.; LACERDA, AUREA C.L.; KANEKO, T.M.Artigo IPEN-doc 17189 Replacement of murine fibroblasts by human fibroblasts irradiated in obtaining feeder layer for the culture of human keratinocytes2011 - YOSHITO, DANIELE; SUFI, BIANCA S.; ALTRAN, SILVANA C.; ISAAC, CESAR; SANTIN, STEFANY P.; ESTEVES PEDRO, NATALIA M.; HERSON, MARISA R.; MATHOR, MONICA B.