EVERTON BONTURIM
2 resultados
Resultados de Busca
Agora exibindo 1 - 2 de 2
Resumo IPEN-doc 24830 Rare earth compounds as smart materials to biological application2017 - FELINTO, M.C.F.C.; SALVADOR, F.F.S.; FRANCISCO, L.H.C.; BONTURIM, EVERTON; BRITO, H.F.; MALTA, O.M.L.; TEOTONIO, E.E.S.Materials containing rare earth metals are receiving increasing attention due to its wide range of potential applications, including bioanalytical, images, dye-sensitized solar cells, nanobiotechnology, catalyses among others. The distinguished spectroscopic properties of lanthanides (intense emission bands, high color purity, long lifetime and high quantum efficiency) make them strong candidates for use as markers or bio- selective detectors. Besides the interest in developing nanoparticles ( NP ) associated with biological materials continues growing rapidly . This interest is mainly motivated by the desire to simultaneously exploit the properties of both the NP and biological components in new hybrid operating devices or materials that can be applied in strategic areas. In this work, we design various materials, synthesized and characterized in several laboratories that are part of the group fluoroimunoensaios inct - INAMI and NanoBio network and that have potential to use as biological markers .An attention to materials that emit in the regions of Vis and IR as the compound of Eu and Nd compounds, RE3 + compounds covered with silica and functionalized, RE3 + complexes dispersed in polymeric matrix and have sharp, etc. luminescence will be discussed. Also it will show these nanoparticles in - action , signaling biological materials at very low concentrations , on the order of nanomolar . The principal studies are connected to the diagnostic field and has been studied mainly Leishmania , PSA , LDL, sickle cell disease, estradiol and Chagas disease.Resumo IPEN-doc 24513 Cashew gun resin doped with Eu(tta)3.(TPPO)2 and Eu(dbm)3.(TPPO) nanoparticle acting as biomaker2017 - FELINTO, MARIA C.F.C.; SALVADOR, FRANCINE F.S.; BONTURIM, EVERTON; BRITO, HERMI F.; SANTOS, PAULO R.; TEOTONIO, ERCULES E.S.; FAUSTINO, WAGNER; MALTA, OSCAR M.L.Anacardium occidentale L., a tree species from the Anacardiaceae family, is native in Brazil growing mostly in the northeastern region. Cashew gum (CG) is one such versatile naturally occurring biopolymer that is finding increasing applications in the pharmaceutical and biotechnology industry. It has been used successfully for many years in the food and beverage industry as a thickening agent and a colloidal stabilizer. Recently, the role of these gums in enveloping controlled drug delivery systems has increased significantly and CG has achieve lot of attraction towards this application [1]. In this work, nanoparticles of Eu(tta)3(TPPO)2 and Eu(dbm)3(TPPO) were tryed to solubilize in the CG water solution improving the dispersion of the nanoparticle complexes, and giving the opportunity to use these materials as biomarker. An 1%(w/w) of the Eu(tta)3(TPPO)2 or Eu(dbm)3(TPPO) nanoparticles were dispersed in a water solution of CG resin. After that, these materials were dried and the products obtained were films. These materials were characterized by infrared spectroscopy, XPD, TGA, SEM, absorption and photoluminescence spectroscopy. The results showed that the materials are crystalline and when doped increase the thermal stability of the CG resin. These films were soluble in water They also have intense luminescence, with emission spectra presenting characteristic internal transitions of 4f6-4f6 configuration of the Eu3+ ion even in water solution (Fig. 1). The addition of Ag0 in the solution improve the intensity of the fluorophore in solution. Intensity parameters in solid phase were determined and the quantum efficiency ~57% corroborate with the idea of use this green material as a biomarker[2].