VIVIANE PEREIRA GOULART
6 resultados
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Artigo IPEN-doc 20857 Biochemical changes in cutaneous squamous cell carcinoma submitted to PDT using ATR-FTIR spectroscopy2015 - LIMA, CASSIO A.; GOULART, VIVIANE P.; CASTRO, PEDRO A.A. de; CORREA, LUCIANA; BENETTI, CAROLINA; ZEZELL, DENISE M.Nonmelanoma skin cancers are the most common form of malignancy in humans. Between the traditional treatment ways, the photodynamic therapy (PDT) is a promising alternative which is minimally invasive and do not requires surgical intervention or exposure to ionizing radiation. The understanding of the cascade of effects playing role in PDT is not fully understood, so that define and understand the biochemical events caused by photodynamic effect will hopefully result in designing better PDT protocols. In this study we investigated the potential of the FTIR spectroscopy to assess the biochemical changes caused by photodynamic therapy after 10 and 20 days of treatment using 5-aminolevulinic acid (ALA) as precursor of the photosensitizer photoporphyrin IX (PpIX). The amplitude values of second derivative from vibrational modes obtained with FTIR spectroscopy showed similar behavior with the morphological features observed in histopathological analysis, which showed active lesions even 20 days after PDT. Thus, the technique has the potential to be used to complement the investigation of the main biochemical changes that photodynamic therapy promotes in tissue.Resumo IPEN-doc 17465 Mechanisms of high intensity lasers for caries prevention and erosion2011 - ANA, P.A.; BACHMANN, L.; BENETTI, C.; GOULART, V.P.; ZEZELL, D.M.Resumo IPEN-doc 16035 FTIR spectroscopy monitoring chemical changes in enamel dentin and bone due to laser irradiation2010 - ZEZELL, DENISE M.; ANA, PATRICIA A.; BENETTI, CAROLINA; QUINTO JUNIOR, JOSE; PEREIRA, THIAGO M.; GOULART, VIVIANEResumo IPEN-doc 15314 Characterization by ATR-FTIR of irradiated bone2009 - BENETTI, C.; SANTOS, M.O.; GOULART, V.P.; ZEZELL, D.M.Resumo IPEN-doc 13507 Determinacao do limiar de ablacao o e coefeciente de absorcao o do osso para o laser de Er, Cr:YSGG2008 - BENETTI, CAROLINA; GOULART, VIVIANE P.; RAELE, MARCUS P.; FREITAS, ANDERSON Z. de; ZEZELL, DENISE M.Artigo IPEN-doc 15924 Composition and crystallographic changes on enamel when irradiated by Nd:YAG or Er,Cr:YSGG lasers and its resistance to demineralization when associated with fluoride2010 - ZEZELL, D.M.; ANA, P.A.; BENETTI, C.; GOULART, V.P.; BACHMANN, L.; TABCHOURY, C.P.M.; CURY, J.A.