CECILIA CHAVES GUEDES E SILVA

Resumo

Possui graduação em Engenharia de Materiais pela Universidade Presbiteriana Mackenzie (1997), mestrado em Tecnologia Nuclear Aplicações pelo Instituto de Pesquisas Energéticas e Nucleares (2000) e doutorado em Tecnologia Nuclear Materiais pelo Instituto de Pesquisas Energéticas e Nucleares (2005). Atualmente é pesquisador do Instituto de Pesquisas Energéticas e Nucleares. Tem experiência na área de Engenharia de Materiais, atuando principalmente nos seguintes temas: materiais cerâmicos, biomateriais e materiais nucleares. (Texto extraído do Currículo Lattes em 08 out. 2021)

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  • Artigo IPEN-doc 25100
    Microstructure, mechanical properties and in vitro biological behavior of silicon nitride ceramics
    2018 - GUEDES-SILVA, CECILIA C.; RODAS, ANDREA C.D.; SILVA, ANTONIO C.; RIBEIRO, CHRISTIANE; CARVALHO, FLAVIO M. de S.; HIGA, OLGA Z.; FERREIRA, THIAGO dos S.
    The bioinert surface of silicon nitride ceramics led us to investigate the additions of SiO2, CaO and Al2O3 in order to aid the liquid phase sintering and improve the mechanical properties and biological behavior of the final materials. The sintered materials reached ca. 97% of theoretical density and total α→β-Si3N4 transformation. The samples had relatively high values of fracture toughness while their elastic modulus values were lower than those of conventional silicon nitride ceramics. Apatite deposits were observed on the surfaces analyzed after SBF (simulated body fluid) immersions, suggesting their bioactivity. Osteoblasts proliferation and calcified matrix were also detected as response to cells/ materials contact. This combination of properties suggests that all studied compositions are promising for applications in biomedical devices. Moreover, compositions with alumina additions and higher silica content had better in vitro biological behavior, densification and mechanical properties, suggesting greater potential to be used in bone substitute devices.