Resveratrol radiomodifier effect on Danio rerio embriolarval assay

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dc.contributor.authorDAMASCENO, KELME C.
dc.contributor.authorMAMEDE, FERNANDA C.S.
dc.contributor.authorCAVALCANTE, ADRIANA K.
dc.contributor.authorROGERO, SIZUE O.
dc.contributor.authorFERREIRA, MONICA L.
dc.contributor.authorROGERO, JOSE R.
dc.coverageInternacionalpt_BR
dc.creator.eventoINTERNATIONAL NUCLEAR ATLANTIC CONFERENCEpt_BR
dc.date.accessioned2018-01-15T10:23:51Z
dc.date.available2018-01-15T10:23:51Z
dc.date.eventoOctober 22-27, 2017pt_BR
dc.description.abstractThe ionizing radiation can cause fatal damages to cells by the direct interaction with DNA and RNA or a series of toxic reactions occasioning chemical and biological changes. There are compounds with radioprotective potential, like resveratrol. For use the organism. Resveratrol is a substance found in peanuts, grapes and wine and its production occurs in plants as a response to physical, chemical and biological stress. Some studies benefits. Danio rerio (zebrafish) is a vertebrate animal and has become the model of several studies related to human diseases, due to its genomes similarity of 70 %, rapid embryonic development and the transparency o the eggs, which make it possible to observe the effects during the test period. The aim of the present study to verify the resveratrol radiomodifier effect on zebrafish during the embryolarval development by modified Fish Embryo Acute Toxicity (FET) (LC50) was 66.9 mg.L-1. Before, to understand the effects of radiation, was carried out the gamma radiation lethal dose (LD50) assay and the LD50 was 25 Gy. With these results the projec study of the radiomodifier effect of resveratrol in the presence of gamma radiationpt_BR
dc.event.siglaINACpt_BR
dc.identifier.citationDAMASCENO, KELME C.; MAMEDE, FERNANDA C.S.; CAVALCANTE, ADRIANA K.; ROGERO, SIZUE O.; FERREIRA, MONICA L.; ROGERO, JOSE R. Resveratrol radiomodifier effect on Danio rerio embriolarval assay. In: INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE, October 22-27, 2017, Belo Horizonte, MG. <b>Proceedings...</b> Rio de Janeiro, RJ: Associação Brasileira de Energia Nuclear, 2017. Disponível em: http://repositorio.ipen.br/handle/123456789/28310.
dc.identifier.orcidhttps://orcid.org/0000-0002-2517-7772
dc.identifier.orcidhttps://orcid.org/0000-0003-3396-6277
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/28310
dc.localRio de Janeiro, RJpt_BR
dc.local.eventoBelo Horizonte, MGpt_BR
dc.publisherAssociação Brasileira de Energia Nuclearpt_BR
dc.rightsopenAccesspt_BR
dc.subjectembryos
dc.subjectfishes
dc.subjectin vivo
dc.subjectlethal doses
dc.subjectradiation effects
dc.subjectradiation protection
dc.subjectradioprotective substances
dc.subjecttoxicity
dc.titleResveratrol radiomodifier effect on Danio rerio embriolarval assaypt_BR
dc.typeTexto completo de eventopt_BR
dspace.entity.typePublication
ipen.autorFERNANDA CAROLINE SILVA MAMEDE
ipen.autorJOSE ROBERTO ROGERO
ipen.autorSIZUE OTA ROGERO
ipen.autorADRIANA KUCHINSKI CAVALCANTE
ipen.autorKELME CARDOSO DAMASCENO
ipen.codigoautor14172
ipen.codigoautor1118
ipen.codigoautor1266
ipen.codigoautor12073
ipen.codigoautor14173
ipen.contributor.ipenauthorFERNANDA CAROLINE SILVA MAMEDE
ipen.contributor.ipenauthorJOSE ROBERTO ROGERO
ipen.contributor.ipenauthorSIZUE OTA ROGERO
ipen.contributor.ipenauthorADRIANA KUCHINSKI CAVALCANTE
ipen.contributor.ipenauthorKELME CARDOSO DAMASCENO
ipen.date.recebimento18-01pt_BR
ipen.event.datapadronizada2017pt_BR
ipen.identifier.ipendoc24145pt_BR
ipen.notas.internasProceedingspt_BR
ipen.type.genreArtigo
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relation.isAuthorOfPublication.latestForDiscoverycd6367e6-cfee-4b53-8417-6b3f9beb876a
sigepi.autor.atividadeDAMASCENO, KELME C.:14173:740:Spt_BR
sigepi.autor.atividadeMAMEDE, FERNANDA C.S.:14172:740:Npt_BR
sigepi.autor.atividadeCAVALCANTE, ADRIANA K.:12073:740:Npt_BR
sigepi.autor.atividadeROGERO, SIZUE O.:1266:740:Npt_BR
sigepi.autor.atividadeROGERO, JOSE R.:1118:740:Npt_BR
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