Distinct dose contributions in proton therapy calculated using MCNP6 and TOPAS
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2019
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REUNIÃO DE TRABALHO SOBRE FÍSICA NUCLEAR NO BRASIL, 42.; ENCONTRO NACIONAL DE FÍSICA DE PARTÍCULAS E CAMPOS, 40.
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The trade-off between the delivery of high doses conformed to a tumor volume, and the restriction of the doses
received by the surrounding healthy tissues and organs is what characterizes the e±ciency of radiotherapeutic
procedures. As a radiotherapy modality, proton therapy stands out in this scenario because it has dosimetric
advantages, which, when combined with technological advances, allows a great potential in the dose distribution
conformity. By modulating the protons Bragg peak as a function of beam energy and delivery time, the
three-dimensional shaped dose distribution generates more pronounced dose gradients, which composes an
ideal technique when preserving organs is a priority. In proton therapy, protons account for much of the dose
deposition. However, as protons travel through matter, secondary particles are created by interactions, including
electrons, neutrons, and gammas. It is believed that the secondary dose, mainly deposited by neutrons, can lead
to secondary cancer, especially in pediatric cases. Therefore, the focus of this work is to study the contribution
of the different particles in the total dose deposition. Monte Carlo simulations were performed with the MCNP6
code and the TOPAS interface (based on GEANT4) to estimate the dose deposition. A simple water simulator
was used and the characteristics of the different beam contributions were investigated. Primary and secondary
dose values were tabulated and discussed. By demonstrating the method of these calculations, the objective of
this work is to serve as a guide for the study of the different contributions of the dose responsible particles in
proton therapy, as well as for understanding how different Monte Carlo codes calculate these contributions.
Como referenciar
BRANCO, I.S.L.; SHORTO, J.M.B.; SIQUEIRA, P.T.D.; YORIYAZ, H. Distinct dose contributions in proton therapy calculated using MCNP6 and TOPAS. In: REUNIÃO DE TRABALHO SOBRE FÍSICA NUCLEAR NO BRASIL, 42.; ENCONTRO NACIONAL DE FÍSICA DE PARTÍCULAS E CAMPOS, 40., 1-5 de setembro, 2019, Campos do Jordão, SP. Resumo... São Paulo, SP: Sociedade Brasileira de Física, 2019. Disponível em: http://repositorio.ipen.br/handle/123456789/32320. Acesso em: 07 Jun 2024.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.