Inhomogeneity in optical properties of rat brain: a study for LLLT dosimetry

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dc.contributor.authorSOUSA, MARCELO V.P.
dc.contributor.authorPRATES, RENATO
dc.contributor.authorKATO, ILKA T.
dc.contributor.authorSABINO, CAETANO P.
dc.contributor.authorYOSHIMURA, TANIA M.
dc.contributor.authorSUZUKI, LUIS C.
dc.contributor.authorMAGALHAES, ANA C.
dc.contributor.authorYOSHIMURA, ELISABETH M.
dc.contributor.authorRIBEIRO, MARTHA S.
dc.contributor.editorHAMBLIN, MICHAEL R.
dc.contributor.editorARANY, PRAVEEN R.
dc.contributor.editorCARROLL, JAMES D.
dc.coverageInternacionalpt_BR
dc.creator.eventoMECHANISMS FOR LOW-LIGHT THERAPY, 8thpt_BR
dc.date.accessioned2017-07-07T12:57:10Z
dc.date.available2017-07-07T12:57:10Z
dc.date.eventoFebruary 02, 2013pt_BR
dc.description.abstractOver the last few years, low-level light therapy (LLLT) has shown an incredible suitability for a wide range of applications for central nervous system (CNS) related diseases. In this therapeutic modality light dosimetry is extremely critical so the study of light propagation through the CNS organs is of great importance. To better understand how light intensity is delivered to the most relevant neural sites we evaluated optical transmission through slices of rat brain point by point. We experimented red (λ = 660 nm) and near infrared (λ = 808 nm) diode laser light analyzing the light penetration and distribution in the whole brain. A fresh Wistar rat (Rattus novergicus) brain was cut in sagittal slices and illuminated with a broad light beam. A high-resolution digital camera was employed to acquire data of transmitted light. Spatial profiles of the light transmitted through the sample were obtained from the images. Peaks and valleys in the profiles show sites where light was less or more attenuated. The peak intensities provide information about total attenuation and the peak widths are correlated to the scattering coefficient at that individual portion of the sample. The outcomes of this study provide remarkable information for LLLT dose-dependent studies involving CNS and highlight the importance of LLLT dosimetry in CNS organs for large range of applications in animal and human diseases.pt_BR
dc.event.siglaSPIEpt_BR
dc.format.extent856905-1 - 856905-6pt_BR
dc.identifier.citationSOUSA, MARCELO V.P.; PRATES, RENATO; KATO, ILKA T.; SABINO, CAETANO P.; YOSHIMURA, TANIA M.; SUZUKI, LUIS C.; MAGALHAES, ANA C.; YOSHIMURA, ELISABETH M.; RIBEIRO, MARTHA S. Inhomogeneity in optical properties of rat brain: a study for LLLT dosimetry. In: HAMBLIN, MICHAEL R. (ed.); ARANY, PRAVEEN R. (ed.); CARROLL, JAMES D. (ed.). In: MECHANISMS FOR LOW-LIGHT THERAPY, 8th, February 02, 2013, San Francisco, CA, USA. <b>Proceedings...</b> Bellingham, WA, USA: International Society for Optics and Photonics, 2013. p. 856905-1 - 856905-6. (SPIE Proceedings Series, 8569). DOI: <a href="https://dx.doi.org/10.1117/12.2002836">10.1117/12.2002836</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/27652.
dc.identifier.doi10.1117/12.2002836pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4203-1134
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/27652
dc.localBellingham, WA, USApt_BR
dc.local.eventoSan Francisco, CA, USApt_BR
dc.publisherInternational Society for Optics and Photonicspt_BR
dc.relation.ispartofseriesSPIE Proceedings Series, 8569pt_BR
dc.rightsopenAccesspt_BR
dc.titleInhomogeneity in optical properties of rat brain: a study for LLLT dosimetrypt_BR
dc.typeTexto completo de eventopt_BR
dspace.entity.typePublication
ipen.autorCAETANO PADIAL SABINO
ipen.autorTANIA MATEUS YOSHIMURA
ipen.autorMARTHA SIMOES RIBEIRO
ipen.autorELISABETH MATEUS YOSHIMURA
ipen.autorLUIS CLAUDIO SUZUKI
ipen.autorILKA TIEMY KATO
ipen.autorRENATO ARAÚJO PRATES
ipen.autorMARCELO VITOR P. SOUSA
ipen.codigoautor9334
ipen.codigoautor10230
ipen.codigoautor574
ipen.codigoautor11189
ipen.codigoautor3953
ipen.codigoautor3089
ipen.codigoautor4028
ipen.codigoautor11188
ipen.contributor.ipenauthorCAETANO PADIAL SABINO
ipen.contributor.ipenauthorTANIA MATEUS YOSHIMURA
ipen.contributor.ipenauthorMARTHA SIMOES RIBEIRO
ipen.contributor.ipenauthorELISABETH MATEUS YOSHIMURA
ipen.contributor.ipenauthorLUIS CLAUDIO SUZUKI
ipen.contributor.ipenauthorILKA TIEMY KATO
ipen.contributor.ipenauthorRENATO ARAÚJO PRATES
ipen.contributor.ipenauthorMARCELO VITOR P. SOUSA
ipen.date.recebimento17-07pt_BR
ipen.event.datapadronizada2013pt_BR
ipen.identifier.ipendoc23888pt_BR
ipen.notas.internasProceedingspt_BR
ipen.type.genreArtigo
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sigepi.autor.atividadeSOUSA, MARCELO V.P.:11188:-1:Spt_BR
sigepi.autor.atividadePRATES, RENATO:4028:920:Npt_BR
sigepi.autor.atividadeKATO, ILKA T.:3089:920:Npt_BR
sigepi.autor.atividadeSABINO, CAETANO P.:9334:920:Npt_BR
sigepi.autor.atividadeYOSHIMURA, TANIA M.:10230:920:Npt_BR
sigepi.autor.atividadeSUZUKI, LUIS C.:3953:920:Npt_BR
sigepi.autor.atividadeYOSHIMURA, ELISABETH M.:11189:-1:Npt_BR
sigepi.autor.atividadeRIBEIRO, MARTHA S.:574:920:Npt_BR
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