Experiment to access Iodine-125 leakage in different vials

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dc.contributor.authorSOUZA, C.D. de
dc.contributor.authorROSTELATO, M.C.M.
dc.contributor.authorZEITUNI, C.
dc.contributor.authorCOSTA, O. da
dc.contributor.authorRODRIGUES, B.T.
dc.contributor.authorGONZALEZ, A.C.
dc.contributor.authorMARQUES, J. de O.
dc.coverageInternacionalpt_BR
dc.date.accessioned2017-10-02T11:35:35Z
dc.date.available2017-10-02T11:35:35Z
dc.date.issued2017pt_BR
dc.description.abstractPurpose: There are several challenges when developing a laboratory to produce radioactive sources. From choosing a prototype to radiation safety, the task is enormous. During the past 15 years, our research group is developing a laboratory to produce iodine-125 seed. These seeds are placed inside the cancer and release radiation directly in the target. The whole production line is full of new process and innovations. Among those, a new chemical reaction that deposit iodine-125 onto silver (core) was developed. This paper presents a comparison between vials in order to access their capability to retain radioactive iodine. Also, the fixation percentage in a silver core was taken into account. This information will be used to select a vial to be implemented at the iodine-125 sources manufacture laboratory. Methods: Vials made with polymers and glass was tested. Iodine-125 were placed in the vials overnight at rt. Seven vials with different materials (glass, dark glass, and plastics) were evaluated. Results: The selected vial (borosilicate glass 1 mL total volume) loss 17.61% of iodine in 24 hours and presented the highest iodine intake. It was noticeable that the vial material influenced both iodine intake and iodine loss. The goal is to maximize the reaction yield to result in a less costly product. Conclusion: We have selected the best vial for our reaction in regards to leakage and yield.pt_BR
dc.format.extent3146-3146pt_BR
dc.identifier.citationSOUZA, C.D. de; ROSTELATO, M.C.M.; ZEITUNI, C.; COSTA, O. da; RODRIGUES, B.T.; GONZALEZ, A.C.; MARQUES, J. de O. Experiment to access Iodine-125 leakage in different vials. <b>Medical Physics</b>, v. 44, n. 6, p. 3146-3146, 2017. Disponível em: http://repositorio.ipen.br/handle/123456789/27822.
dc.identifier.fasciculo6pt_BR
dc.identifier.issn0094-2405pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-7303-6720
dc.identifier.orcidhttps://orcid.org/0000-0003-2943-6097
dc.identifier.orcidhttp://orcid.org/0000-0003-1335-8864
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/27822
dc.identifier.vol44pt_BR
dc.relation.ispartofMedical Physicspt_BR
dc.rightsopenAccesspt_BR
dc.subjectiodine 125
dc.subjectleak detectors
dc.subjectsilver
dc.subjectborosilicate glass
dc.titleExperiment to access Iodine-125 leakage in different vialspt_BR
dc.typeResumos em periódicospt_BR
dspace.entity.typePublication
ipen.autorBRUNA TEIGA RODRIGUES
ipen.autorANDREZA APARECIDA DEL CARMEN CASTRO GONZALEZ
ipen.autorJOSE RONALDO DE OLIVEIRA MARQUES
ipen.autorOSVALDO LUIZ DA COSTA
ipen.autorCARLOS ALBERTO ZEITUNI
ipen.autorMARIA ELISA CHUERY MARTINS ROSTELATO
ipen.autorCARLA DARUICH DE SOUZA
ipen.codigoautor11600
ipen.codigoautor14495
ipen.codigoautor1515
ipen.codigoautor669
ipen.codigoautor944
ipen.codigoautor7
ipen.codigoautor7717
ipen.contributor.ipenauthorBRUNA TEIGA RODRIGUES
ipen.contributor.ipenauthorANDREZA APARECIDA DEL CARMEN CASTRO GONZALEZ
ipen.contributor.ipenauthorJOSE RONALDO DE OLIVEIRA MARQUES
ipen.contributor.ipenauthorOSVALDO LUIZ DA COSTA
ipen.contributor.ipenauthorCARLOS ALBERTO ZEITUNI
ipen.contributor.ipenauthorMARIA ELISA CHUERY MARTINS ROSTELATO
ipen.contributor.ipenauthorCARLA DARUICH DE SOUZA
ipen.date.recebimento17-10pt_BR
ipen.identifier.fi2.617pt_BR
ipen.identifier.ipendoc23127pt_BR
ipen.range.fi1.500 - 2.999
ipen.type.genreResumo
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relation.isAuthorOfPublicationda77b491-04ff-4c68-aa65-dead9208a48c
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relation.isAuthorOfPublication.latestForDiscovery866434dc-2634-4567-8b4b-04e5ce06bf04
sigepi.autor.atividadeSOUZA, C.D. de:7717:230:Spt_BR
sigepi.autor.atividadeROSTELATO, M.C.M.:7:230:Npt_BR
sigepi.autor.atividadeZEITUNI, C.:944:230:Npt_BR
sigepi.autor.atividadeCOSTA, O. da:669:230:Npt_BR
sigepi.autor.atividadeRODRIGUES, B.T.:11600:230:Npt_BR
sigepi.autor.atividadeGONZALEZ, A.C.:14495:230:Npt_BR
sigepi.autor.atividadeMARQUES, J. de O.:1515:230:Npt_BR
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