Alternative for the quality control of antivenom production proposed by Lonomia obliqua caterpillars using analytic techniques

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dc.contributor.authorLEÃO, ANICARINE R.pt_BR
dc.contributor.authorZAMBONI, CIBELE B.pt_BR
dc.contributor.authorSILVA, DALTON G.N. dapt_BR
dc.contributor.authorMENDONÇA, RONALDO Z.pt_BR
dc.contributor.authorSIMONS, SIMONE M.pt_BR
dc.coverageInternacionalpt_BR
dc.creator.eventoBRAZILIAN MEETING ON NUCLEAR PHYSICS, 41thpt_BR
dc.date.accessioned2019-08-21T19:26:05Z
dc.date.available2019-08-21T19:26:05Z
dc.date.eventoSeptember 2-6, 2018pt_BR
dc.description.abstractThe caterpillars Lonomia obliqua Walker (L. obliqua) species, commonly found in southern Brazil, is very poisonous and can cause severe damage in human (haemorrhagic e®ects) after the contact that can lead to death [1]. The ¯rst case of poisoning (registered in Brazil) occurred in 1989 and the average number of accidents is closer to 500/year [2]. Nowadays, the Butantan Institute (Research Center at S~ao Paulo city, Brazil) is active in the production of this antiveneom in Latin America; it is the only producer of antilonomic serum. However, in the last two years, this caterpillar has been found in other regions due, mainly, to the expansion and destruction of natural ecosystems provide their growth in all regions of the country. To ensure that the antivenom produced (considering the di®erent origins) can be used for the manufacture of unaltered antilonomic serum, it is necessary to standardize this antidote. We intend to standardize the serum obtained from di®erent regions of origin using X-Ray Fluorescence (XRF). The experimental conditions using the compact XRF spectrometers (X-123SDD, Amptek) were optimized. The results will be compared and validated with INAA analysis.pt_BR
dc.event.siglaRTFNBpt_BR
dc.format.extent1-1pt_BR
dc.identifier.citationLEÃO, ANICARINE R.; ZAMBONI, CIBELE B.; SILVA, DALTON G.N. da; MENDONÇA, RONALDO Z.; SIMONS, SIMONE M. Alternative for the quality control of antivenom production proposed by Lonomia obliqua caterpillars using analytic techniques. In: BRAZILIAN MEETING ON NUCLEAR PHYSICS, 41th, September 2-6, 2018, Maresias, SP. <b>Abstract...</b> São Paulo: Sociedade Brasileira de Física, 2018. p. 1-1. Disponível em: http://repositorio.ipen.br/handle/123456789/30113.
dc.identifier.orcidhttps://orcid.org/0000-0001-7766-2692
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/30113
dc.localSão Paulopt_BR
dc.local.eventoMaresias, SPpt_BR
dc.publisherSociedade Brasileira de Físicapt_BR
dc.rightsopenAccesspt_BR
dc.titleAlternative for the quality control of antivenom production proposed by Lonomia obliqua caterpillars using analytic techniquespt_BR
dc.typeResumo de eventos científicospt_BR
dspace.entity.typePublication
ipen.autorDALTON GIOVANNI NOGUEIRA DA SILVA
ipen.autorCIBELE BUGNO ZAMBONI
ipen.autorANICARINE RIBEIRO LEAO
ipen.codigoautor13948
ipen.codigoautor267
ipen.codigoautor15238
ipen.contributor.ipenauthorDALTON GIOVANNI NOGUEIRA DA SILVA
ipen.contributor.ipenauthorCIBELE BUGNO ZAMBONI
ipen.contributor.ipenauthorANICARINE RIBEIRO LEAO
ipen.date.recebimento19-08
ipen.event.datapadronizada2018pt_BR
ipen.identifier.ipendoc25907pt_BR
ipen.notas.internasAbstractpt_BR
ipen.type.genreResumo
relation.isAuthorOfPublicationbc63fe9c-45a3-4902-9c00-76b77f4a74d2
relation.isAuthorOfPublication563d95e5-227e-456d-a1d7-4bb051ae51ba
relation.isAuthorOfPublication2f9adfbd-8a3e-4d06-9250-43f780b661d9
relation.isAuthorOfPublication.latestForDiscovery2f9adfbd-8a3e-4d06-9250-43f780b661d9
sigepi.autor.atividadeSILVA, DALTON G.N. da:13948:310:Npt_BR
sigepi.autor.atividadeZAMBONI, CIBELE B.:267:310:Npt_BR
sigepi.autor.atividadeLEÃO, ANICARINE R.:15238:-1:S
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