Histopathological changes in zebrafish exposed to sublethal concentrations of 89nm silver nanoparticles for application in environmental diagnostics

Página do item simplificado
dc.contributor.authorAZEVEDO, JULIANA de S.pt_BR
dc.contributor.authorQUINTINO, MARILIA T.A.pt_BR
dc.contributor.authorROGERO, SIZUE O.pt_BR
dc.contributor.authorZAMPIERI, MARIA C.T.pt_BR
dc.contributor.authorROGERO, JOSE R.pt_BR
dc.coverageInternacionalpt_BR
dc.date.accessioned2020-06-19T19:00:13Z
dc.date.available2020-06-19T19:00:13Z
dc.date.issued2020pt_BR
dc.description.abstractThe use of biomarkers as indicators of environmental contamination has been shown to be an excellent indicator of changes in biota. Histopathological lesions are commonly used in biomonitoring studies as they provide information regarding both acute and chronic exposure. The use of nanoparticle materials has been widespread in recent years. However, not much is known about their ecological effects on the natural environment. Thus, the aim of this study was to assess the sublethal effects of silver nanoparticles (AgNP) with mean diameters of 89nm in the zebrafish Danio rerio by the determination of the LC50; 48 h and histopathological assays in gills. The obtained LC50; 48 h was 8.18 mgL 1. The histopathological gill assessment showed primary responses indicative of acute damage as aneurysms (32.76%), hyperplasia (20.69%) and partial (30.17%) and total lamellar fusion (6.9%) of secondary lamellae. No deposition of AgNP was observed in any tested sample gills, suggesting other organs target to absorption and detoxification. In fact, the AgNP causes sublethal damage in the gills of zebrafish but is not able to accumulate in this tissue. Finally, the data shown in this study contribute to the construction of a database on the AgNP exposure in aquatic organisms.pt_BR
dc.format.extent1207-1220pt_BR
dc.identifier.citationAZEVEDO, JULIANA de S.; QUINTINO, MARILIA T.A.; ROGERO, SIZUE O.; ZAMPIERI, MARIA C.T.; ROGERO, JOSE R. Histopathological changes in zebrafish exposed to sublethal concentrations of 89nm silver nanoparticles for application in environmental diagnostics. <b>Human and Ecological Risk Assessment</b>, v. 26, n. 5, p. 1207-1220, 2020. DOI: <a href="https://dx.doi.org/10.1080/10807039.2018.1560219">10.1080/10807039.2018.1560219</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/31328.
dc.identifier.doi10.1080/10807039.2018.1560219pt_BR
dc.identifier.fasciculo5pt_BR
dc.identifier.issn1080-7039pt_BR
dc.identifier.orcid0000-0002-2517-7772pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-2517-7772
dc.identifier.orcidhttps://orcid.org/0000-0003-3396-6277
dc.identifier.percentilfi75.73pt_BR
dc.identifier.percentilfiCiteScore78.67
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/31328
dc.identifier.vol26pt_BR
dc.relation.ispartofHuman and Ecological Risk Assessmentpt_BR
dc.rightsopenAccesspt_BR
dc.subjectbiological markers
dc.subjectenvironment
dc.subjectmonitoring
dc.subjectenvironmental quality
dc.subjectgills
dc.subjectfishes
dc.subjectenvironmental effects
dc.subjectwater pollution
dc.subjectbioassay
dc.subjecttoxic materials
dc.subjecthistology
dc.subjectpathology
dc.subjectrisk assessment
dc.titleHistopathological changes in zebrafish exposed to sublethal concentrations of 89nm silver nanoparticles for application in environmental diagnosticspt_BR
dc.typeArtigo de periódicopt_BR
dspace.entity.typePublication
ipen.autorJOSE ROBERTO ROGERO
ipen.autorMARIA CRISTINA TESSARI ZAMPIERI
ipen.autorSIZUE OTA ROGERO
ipen.codigoautor1118
ipen.codigoautor7506
ipen.codigoautor1266
ipen.contributor.ipenauthorJOSE ROBERTO ROGERO
ipen.contributor.ipenauthorMARIA CRISTINA TESSARI ZAMPIERI
ipen.contributor.ipenauthorSIZUE OTA ROGERO
ipen.date.recebimento20-06
ipen.identifier.fi5.190pt_BR
ipen.identifier.fiCiteScore5.4
ipen.identifier.ipendoc25779pt_BR
ipen.identifier.iwosWoSpt_BR
ipen.identifier.ods3
ipen.range.fi4.500 - 5.999
ipen.range.percentilfi75.00 - 100.00
ipen.type.genreArtigo
relation.isAuthorOfPublication7fa01758-0891-4c3a-a4de-6b2451991fc7
relation.isAuthorOfPublicationbc7a8674-7178-4e7e-89e5-a8408c7860db
relation.isAuthorOfPublicationadecaf83-1d61-4fa2-b7e6-4cf91494610d
relation.isAuthorOfPublication.latestForDiscoveryadecaf83-1d61-4fa2-b7e6-4cf91494610d
sigepi.autor.atividadeROGERO, JOSE R.:1118:740:Npt_BR
sigepi.autor.atividadeZAMPIERI, MARIA C.T.:7506:710:Npt_BR
sigepi.autor.atividadeROGERO, SIZUE O.:1266:740:Npt_BR
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
25779.pdf
Tamanho:
1.98 MB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar
Coleções
Periódicos