The effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEG

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dc.contributor.authorSOARES, JAQUELINE J.S.
dc.contributor.authorJACOVONE, RAYNARA M.S.
dc.contributor.authorSANTOS, PAULO S.
dc.contributor.authorZAIM, MARCIO H.
dc.contributor.authorFARIA, DALVA L.A. de
dc.contributor.authorSAKATA, SOLANGE K.
dc.coverageInternacionalpt_BR
dc.creator.eventoINTERNATIONAL NUCLEAR ATLANTIC CONFERENCEpt_BR
dc.date.accessioned2018-01-17T11:41:11Z
dc.date.available2018-01-17T11:41:11Z
dc.date.eventoOctober 22-27, 2017pt_BR
dc.description.abstractThe functionalization of graphene oxide (GO) with polyethylene glycol (PEG) has been widely used in drug delivery systems. This nanocomposite exhibits excellent stability in the presence of high concentrations of salts and proteins and shows to be less toxic than its raw form in vitro and in vivo. However, it must be sterilized before use in the medical field and the gamma irradiation shows a promising option for this purpose. Sterilization by ionizing energy through gamma rays, generated by Cobalt-60 self-disintegration, consists in exposing the materials to short electromagnetic waves. The irradiation process provides substantial advantages when compared to thermal and chemical processes such as more precise control of the process, production of products with superior qualities, lower energy consumption and less environmental pollution. In this work the effect of gamma radiation on the structure of GO and GO functionalized com Amino-PEG (GO-PEG-NH2) irradiated with different doses (15, 25, 35 and 50 kGy) and rate dose 7.31 kGy.h-1 was evaluated. The analyses were performed by Fourier-transform infrared spectroscopy (FT-IR) and Raman spectroscopy. The results showed that the methods for the synthesis of GO and GO-PEG-NH2 was effective since there was confirmation of the surface oxidation of materials and functionalization with the PEG-NH2 and the sterilization by gamma radiation does not caused any defects on materials.pt_BR
dc.event.siglaINACpt_BR
dc.identifier.citationSOARES, JAQUELINE J.S.; JACOVONE, RAYNARA M.S.; SANTOS, PAULO S.; ZAIM, MARCIO H.; FARIA, DALVA L.A. de; SAKATA, SOLANGE K. The effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEG. In: INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE, October 22-27, 2017, Belo Horizonte, MG. <b>Proceedings...</b> Rio de Janeiro, RJ: Associação Brasileira de Energia Nuclear, 2017. Disponível em: http://repositorio.ipen.br/handle/123456789/28340.
dc.identifier.orcidhttps://orcid.org/0000-0001-6072-5853
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/28340
dc.localRio de Janeiro, RJpt_BR
dc.local.eventoBelo Horizonte, MGpt_BR
dc.publisherAssociação Brasileira de Energia Nuclearpt_BR
dc.rightsopenAccesspt_BR
dc.subjectcobalt 60
dc.subjectdose rates
dc.subjectfourier transformation
dc.subjectgamma radiation
dc.subjectgraphene
dc.subjectinfrared spectra
dc.subjectpolyethylene glycols
dc.subjectradiation doses
dc.subjectradiation effects
dc.subjectraman spectroscopy
dc.subjectsterilization
dc.subjectsynthesis
dc.titleThe effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEGpt_BR
dc.typeTexto completo de eventopt_BR
dspace.entity.typePublication
ipen.autorPAULO DE SOUZA SANTOS
ipen.autorSOLANGE KAZUMI SAKATA
ipen.autorRAYNARA MARIA SILVA JACOVONE
ipen.autorJAQUELINE JAMARA SOUZA SOARES
ipen.codigoautor4074
ipen.codigoautor7038
ipen.codigoautor14300
ipen.codigoautor14313
ipen.contributor.ipenauthorPAULO DE SOUZA SANTOS
ipen.contributor.ipenauthorSOLANGE KAZUMI SAKATA
ipen.contributor.ipenauthorRAYNARA MARIA SILVA JACOVONE
ipen.contributor.ipenauthorJAQUELINE JAMARA SOUZA SOARES
ipen.date.recebimento18-01pt_BR
ipen.event.datapadronizada2017pt_BR
ipen.identifier.ipendoc24175pt_BR
ipen.notas.internasProceedingspt_BR
ipen.type.genreArtigo
relation.isAuthorOfPublication580f004e-82b5-446f-8853-cc50707b42fd
relation.isAuthorOfPublicationfb62f288-104d-4352-aed0-a18e0da21a1b
relation.isAuthorOfPublicationda20f0e7-9926-4e06-ae80-ccbc18ec0806
relation.isAuthorOfPublicationcd8afcda-d573-47ce-baa2-ad03bf07b780
relation.isAuthorOfPublication.latestForDiscoverycd8afcda-d573-47ce-baa2-ad03bf07b780
sigepi.autor.atividadeSOARES, JAQUELINE J.S.:14313:220:Spt_BR
sigepi.autor.atividadeJACOVONE, RAYNARA M.S.:14300:220:Npt_BR
sigepi.autor.atividadeSANTOS, PAULO S.:4074:240:Npt_BR
sigepi.autor.atividadeSAKATA, SOLANGE K.:7038:220:Npt_BR
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