Estimate of S-values for children due to six positron emitting radionuclides used in PET examinations

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dc.contributor.authorBELINATO, WALMIR
dc.contributor.authorSANTOS, WILLIAM S.
dc.contributor.authorPERINI, ANA P.
dc.contributor.authorNEVES, LUCIO P.
dc.contributor.authorCALDAS, LINDA V.E.
dc.contributor.authorSOUZA, DIVANIZIA N.
dc.coverageInternacionalpt_BR
dc.date.accessioned2017-03-16T12:25:55Z
dc.date.available2017-03-16T12:25:55Z
dc.date.issued2017pt_BR
dc.description.abstractPositron emission tomography (PET) has revolutionized the diagnosis of cancer since its conception. When combined with computed tomography (CT), PET/CT performed in children produces highly accurate diagnoses from images of regions affected by malignant tumors. Considering the high risk to children when exposed to ionizing radiation, a dosimetric study for PET/CT procedures is necessary. Specific absorbed fractions (SAF) were determined for monoenergetic photons and positrons, as well as the S-values for six positron emitting radionuclides (11C, 13N, 18F, 68Ga, 82Rb, 15O), and 22 source organs. The study was performed for six pediatric anthropomorphic hybrid models, including the newborn and 1 year hermaphrodite, 5 and 10-year-old male and female, using the Monte Carlo N-Particle eXtended code (MCNPX, version 2.7.0). The results of the SAF in source organs and S-values for all organs showed to be inversely related to the age of the phantoms, which includes the variation of body weight. The results also showed that radionuclides with higher energy peak emission produces larger auto absorbed S-values due to local dose deposition by positron decay. The S-values for the source organs are considerably larger due to the interaction of tissue with non-penetrating particles (electrons and positrons) and present a linear relationship with the phantom body masses. The results of the Svalues determined for positron-emitting radionuclides can be used to assess the radiation dose delivered to pediatric patients subjected to PET examination in clinical settings. The novelty of this work is associated with the determination of auto absorbed S-values, in six new pediatric virtual anthropomorphic phantoms, for six emitting positrons, commonly employed in PET exams.pt_BR
dc.format.extent51-56pt_BR
dc.identifier.citationBELINATO, WALMIR; SANTOS, WILLIAM S.; PERINI, ANA P.; NEVES, LUCIO P.; CALDAS, LINDA V.E.; SOUZA, DIVANIZIA N. Estimate of S-values for children due to six positron emitting radionuclides used in PET examinations. <b>Radiation Physics and Chemistry</b>, v. 140, p. 51-56, 2017. DOI: <a href="https://dx.doi.org/10.1016/j.radphyschem.2017.02.038">10.1016/j.radphyschem.2017.02.038</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/27177.
dc.identifier.doi10.1016/j.radphyschem.2017.02.038pt_BR
dc.identifier.issn0969-806Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-7362-2455
dc.identifier.percentilfi43.27en
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/27177
dc.identifier.vol140pt_BR
dc.relation.ispartofRadiation Physics and Chemistrypt_BR
dc.rightsopenAccesspt_BR
dc.subjectanimal tissues
dc.subjectcarbon 11
dc.subjectfluorine 18
dc.subjectgallium 68
dc.subjectemission
dc.subjectionizing radiations
dc.subjectmonte carlo method
dc.subjectneoplasms
dc.subjectorgans
dc.subjectphantoms
dc.subjectpositron computed tomography
dc.subjectradiation doses
dc.titleEstimate of S-values for children due to six positron emitting radionuclides used in PET examinationspt_BR
dc.typeArtigo de periódicopt_BR
dspace.entity.typePublication
ipen.autorLUCIO PEREIRA NEVES
ipen.autorLINDA V. E. CALDAS
ipen.autorWILLIAM S. SANTOS
ipen.codigoautor8760
ipen.codigoautor1495
ipen.codigoautor11952
ipen.contributor.ipenauthorLUCIO PEREIRA NEVES
ipen.contributor.ipenauthorLINDA V. E. CALDAS
ipen.contributor.ipenauthorWILLIAM S. SANTOS
ipen.date.recebimento17-03pt_BR
ipen.identifier.fi1.435pt_BR
ipen.identifier.ipendoc23524pt_BR
ipen.identifier.iwosWoS
ipen.identifier.ods3
ipen.range.fi0.001 - 1.499
ipen.range.percentilfi25.00 - 49.99
ipen.type.genreArtigo
relation.isAuthorOfPublication31957f62-5aa2-454a-b63e-efb27beb65a0
relation.isAuthorOfPublication7f46d4f4-dfd6-4485-a767-10df5b4f4f13
relation.isAuthorOfPublication8a934cbb-80a1-48d9-a6a3-5b724fbf1e27
relation.isAuthorOfPublication.latestForDiscovery8a934cbb-80a1-48d9-a6a3-5b724fbf1e27
sigepi.autor.atividadeSANTOS, WILLIAM S.:11952:-1:Npt_BR
sigepi.autor.atividadeNEVES, LUCIO P.:8760:330:Npt_BR
sigepi.autor.atividadeCALDAS, LINDA V.E.:1495:330:Npt_BR
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