Synthesis of polymeric gels crosslinked by ionizing radiation for treatment of cutaneous leishmaniasis

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dc.contributor.authorOLIVEIRA, MARIA J.A. dept_BR
dc.contributor.authorMOREIRA, EDSON G.pt_BR
dc.contributor.authorSALVADOR, PABLO A.V.pt_BR
dc.contributor.authorALCANTARA, MARA T.S.pt_BR
dc.contributor.authorLUGAO, ADEMAR B.pt_BR
dc.coverageInternacionalpt_BR
dc.creator.eventoINTERNATIONAL NUCLEAR ATLANTIC CONFERENCEpt_BR
dc.date.accessioned2020-01-10T16:40:40Z
dc.date.available2020-01-10T16:40:40Z
dc.date.eventoOctober 21-25, 2019pt_BR
dc.description.abstractIonizing radiation is a very efficient, versatile and clean tool for modifying polymers for various applications, including in the biomedical area. The advantages of using radiation include the ability to process materials in any physical form, at a convenient temperature, often at room temperature. There is no need for the use of initiators or other chemicals and it is easily carried out with high reliability and does not generate any waste. In the research support area, several materials have been treated in order to find correlations between the applied dose and some property of the material susceptible to be modified with gamma radiation. This study proposes the development of polymeric gels (cream) with Glucantime (Sb V) and gel (cream) with silver nanoparticles, for alternative treatment of cutaneous Leishmaniasis. A cobalt-60 gamma irradiation source was used for crosslinking the polymers, forming the silver nanoparticles and simultaneous sterilization, leaving the product ready for use. Polymeric gels were characterized by physico-chemical techniques, instrumental nêutron activation analysis (INAA), scanning electron microscopy (SEM), and transmission electron microscopy (TEM).pt_BR
dc.event.siglaINACpt_BR
dc.format.extent2276-2283pt_BR
dc.identifier.citationOLIVEIRA, MARIA J.A. de; MOREIRA, EDSON G.; SALVADOR, PABLO A.V.; ALCANTARA, MARA T.S.; LUGAO, ADEMAR B. Synthesis of polymeric gels crosslinked by ionizing radiation for treatment of cutaneous leishmaniasis. In: INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE, October 21-25, 2019, Santos, SP. <b>Proceedings...</b> Rio de Janeiro: Associação Brasileira de Energia Nuclear, 2019. p. 2276-2283. Disponível em: http://repositorio.ipen.br/handle/123456789/30622.
dc.identifier.orcid0000-0002-1737-3191pt_BR
dc.identifier.orcid0000-0003-4168-1626pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1737-3191
dc.identifier.orcidhttp://orcid.org/0000-0003-4168-1626
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/30622
dc.localRio de Janeiropt_BR
dc.local.eventoSantos, SPpt_BR
dc.publisherAssociação Brasileira de Energia Nuclear
dc.rightsopenAccesspt_BR
dc.subjectcobalt 60
dc.subjectcross-linking
dc.subjectgels
dc.subjectnanoparticles
dc.subjectneutron activation analysis
dc.subjectpolymers
dc.subjectprotozoa
dc.subjectsilver
dc.subjectskin diseases
dc.subjecttherapeutic uses
dc.subjecttransmission electron microscopy
dc.titleSynthesis of polymeric gels crosslinked by ionizing radiation for treatment of cutaneous leishmaniasispt_BR
dc.typeTexto completo de eventopt_BR
dspace.entity.typePublication
ipen.autorMARA TANIA S. ALCANTARA
ipen.autorADEMAR BENEVOLO LUGAO
ipen.autorPABLO ANTONIO VASQUEZ SALVADOR
ipen.autorEDSON GONCALVES MOREIRA
ipen.autorMARIA JOSE ALVES DE OLIVEIRA
ipen.codigoautor3820
ipen.codigoautor339
ipen.codigoautor3075
ipen.codigoautor860
ipen.codigoautor3310
ipen.contributor.ipenauthorMARA TANIA S. ALCANTARA
ipen.contributor.ipenauthorADEMAR BENEVOLO LUGAO
ipen.contributor.ipenauthorPABLO ANTONIO VASQUEZ SALVADOR
ipen.contributor.ipenauthorEDSON GONCALVES MOREIRA
ipen.contributor.ipenauthorMARIA JOSE ALVES DE OLIVEIRA
ipen.date.recebimento20-01
ipen.event.datapadronizada2019pt_BR
ipen.identifier.ipendoc26271pt_BR
ipen.notas.internasProceedingspt_BR
ipen.type.genreArtigo
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relation.isAuthorOfPublication.latestForDiscoverydb19966e-6f74-43fc-84b1-c24c1d826e0c
sigepi.autor.atividadeLUGAO, ADEMAR B.:339:740:Npt_BR
sigepi.autor.atividadeALCANTARA, MARA T.S.:3820:-1:Npt_BR
sigepi.autor.atividadeSALVADOR, PABLO A.V.:3075:240:Npt_BR
sigepi.autor.atividadeMOREIRA, EDSON G.:860:320:Npt_BR
sigepi.autor.atividadeOLIVEIRA, MARIA J.A. de:3310:750:Spt_BR
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