Levels of Polonium-210 in brain and pulmonary tissues

Página do item simplificado
dc.contributor.authorSANTOS, NATHALIA V. dospt_BR
dc.contributor.authorVIEIRA, CAROLINA L.Z.pt_BR
dc.contributor.authorSALDIVA, PAULO H.N.pt_BR
dc.contributor.authorMAZZILLI, BARBARA P.pt_BR
dc.contributor.authorSAIKI, MITIKOpt_BR
dc.contributor.authorSAUEIA, CATIA H.pt_BR
dc.contributor.authorDE ANDRE, CARMEN D.S.pt_BR
dc.contributor.authorJUSTO, LISIE T.pt_BR
dc.contributor.authorNISTI, MARCELO B.pt_BR
dc.contributor.authorKOUTRAKIS, PETROSpt_BR
dc.coverageInternacionalpt_BR
dc.date.accessioned2020-04-06T19:55:20Z
dc.date.available2020-04-06T19:55:20Z
dc.date.issued2020pt_BR
dc.description.abstractThe accumulation of detectable amounts of radon progeny in human tissues may be a risk factor for development and progression of chronic diseases. In this preliminary study, we analyzed the levels of alpha-emitting radon progeny Polonium-210 (210Po) in the olfactory epithelium, olfactory bulb, frontal lobe, and lung tissues in cadavers from the city of Sao Paulo, SP, Brazil. We also assessed the association between 210Po levels and exposure parameters for urban air pollution using linear regression models adjusted for age, sex, smoke, time living in Sao Paulo, daily commuting, socioeconomic index, and anthracosis (traffic-related black carbon accumulation in the pleural region and in lymph). Our findings show that the concentration of 210Po was associated with anthracosis in lungs of nonsmokers (coefficient = 6.0; standard error = 2.9; p = 0.04). Individuals with lower socioeconomic status also had significantly higher 210Po levels in lungs (coefficient = −1.19; standard error = 0.58; p = 0.042). The olfactory bulb had higher 210Po levels than either olfactory epithelium (p = 0.071), frontal lobe (p < 0.001), or lungs (p = 0.037). Our findings of the deposition of 210Po in autopsy tissues suggest that airborne radionuclides may contribute to the development of chronic diseases, including neurodegenerative diseases.pt_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorshipIDFAPESP: 13/21728-2; 16/23129-7; 16/22793-0; 16/03461-7pt_BR
dc.description.sponsorshipIDCNPq: 304126/2015-2; 300835/95-7pt_BR
dc.format.extent1-7pt_BR
dc.identifier.citationSANTOS, NATHALIA V. dos; VIEIRA, CAROLINA L.Z.; SALDIVA, PAULO H.N.; MAZZILLI, BARBARA P.; SAIKI, MITIKO; SAUEIA, CATIA H.; DE ANDRE, CARMEN D.S.; JUSTO, LISIE T.; NISTI, MARCELO B.; KOUTRAKIS, PETROS. Levels of Polonium-210 in brain and pulmonary tissues: preliminary study in autopsies conducted in the city of São Paulo, Brazil. <b>Scientific Reports</b>, v. 10, n. 1, p. 1-7, 2020. DOI: <a href="https://dx.doi.org/10.1038/s41598-019-56973-z">10.1038/s41598-019-56973-z</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/31092.
dc.identifier.doi10.1038/s41598-019-56973-zpt_BR
dc.identifier.fasciculo1pt_BR
dc.identifier.issn2045-2322pt_BR
dc.identifier.orcid0000-0003-2197-3592pt_BR
dc.identifier.orcid0000-0001-7174-9703pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-7174-9703
dc.identifier.percentilfi77.40pt_BR
dc.identifier.percentilfiCiteScore93.00
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/31092
dc.identifier.vol10pt_BR
dc.relation.ispartofScientific Reportspt_BR
dc.rightsopenAccesspt_BR
dc.subjectbody composition
dc.subjectautopsy
dc.subjectpolonium 210
dc.subjectprogeny
dc.subjectradon
dc.subjectanimal tissues
dc.subjectlungs
dc.subjectbrain
dc.subjectepithelium
dc.subjecttobacco smokes
dc.subjectair pollution
dc.subjecthuman populations
dc.subjecturban populations
dc.subjectbrazil
dc.titleLevels of Polonium-210 in brain and pulmonary tissuespt_BR
dc.typeArtigo de periódicopt_BR
dspace.entity.typePublication
ipen.autorMARCELO BESSA NISTI
ipen.autorCATIA HELOISA ROSIGNOLI SAUEIA
ipen.autorMITIKO SAIKI
ipen.autorBARBARA PACI MAZZILLI
ipen.codigoautor639
ipen.codigoautor1986
ipen.codigoautor1178
ipen.codigoautor45
ipen.contributor.ipenauthorMARCELO BESSA NISTI
ipen.contributor.ipenauthorCATIA HELOISA ROSIGNOLI SAUEIA
ipen.contributor.ipenauthorMITIKO SAIKI
ipen.contributor.ipenauthorBARBARA PACI MAZZILLI
ipen.date.recebimento20-04
ipen.identifier.fi4.379pt_BR
ipen.identifier.fiCiteScore7.1
ipen.identifier.ipendoc26879pt_BR
ipen.identifier.iwosWoSpt_BR
ipen.identifier.ods3
ipen.identifier.ods11
ipen.range.fi3.000 - 4.499
ipen.range.percentilfi75.00 - 100.00
ipen.subtitulopreliminary study in autopsies conducted in the city of São Paulo, Brazilpt_BR
ipen.type.genreArtigo
relation.isAuthorOfPublicationb935386b-b487-4939-a875-79c100ea555f
relation.isAuthorOfPublication53e5a003-b773-4e77-ac4d-ab0da69a0d2e
relation.isAuthorOfPublication78e9df14-8ccf-4a31-a02f-4a8a4c111c14
relation.isAuthorOfPublication7e8b6143-512f-4b43-87a9-eb5ea497807f
relation.isAuthorOfPublication.latestForDiscovery7e8b6143-512f-4b43-87a9-eb5ea497807f
sigepi.autor.atividadeNISTI, MARCELO B.:639:340:Npt_BR
sigepi.autor.atividadeSAUEIA, CATIA H.:1986:340:Npt_BR
sigepi.autor.atividadeSAIKI, MITIKO:1178:320:Npt_BR
sigepi.autor.atividadeMAZZILLI, BARBARA P.:45:340:Npt_BR
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
26879.pdf
Tamanho:
948.04 KB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar
Coleções
Periódicos