Evaluation of the use of sterilized and non-sterilized Peruibe Black Mud in patients with knee osteoarthritis
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2021
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International Journal of Environmental Research and Public Health
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This study aimed to evaluate the effects of treatment with Peruíbe Black Mud (PBM) on the
clinical parameters and quality of life of patients with knee osteoarthritis and to compare the effects
of PBM samples simply matured in seawater and PBM sterilized by gamma radiation. A controlled,
double-blind trial was conducted with 41 patients divided into two treatment groups composed of
20 and 21 patients: one group was treated with matured PBM and the other with sterilized PBM.
Evaluations were done using theWestern Ontario and McMaster Universities Osteoarthritis Index
(WOMAC) and the Medical Outcomes Study Short Form 36 (SF-36) questionnaires, the Kellgren
and Lawrence (KL) radiographic scale, and the quantification of the serum levels of inflammatory
biomarkers. An improvement in pain, physical functions, and quality of life was observed in all of
the patients who underwent treatment with both simply matured and sterilized PBM. Nine patients
showed remission in the KL radiographic scale, but no statistically significant differences were
observed in the serum levels of inflammatory mediators before or after treatment. Peruíbe Black
Mud proves to be a useful tool as an adjuvant treatment for knee osteoarthritis (OA), as shown by
the results of the WOMAC and SF-36 questionnaires and by the remission of the radiographic grade
of some patients on the Kellgren and Lawrence scale.
Como referenciar
GOUVEA, PAULO F.M.; BRITSCHKA, ZELIA M.N.; GOMES, CRISTINA de O.M.S.; QUEIROZ, NICOLLE G.T. de; SALVADOR, PABLO A.V.; SILVA, PAULO S.C. Evaluation of the use of sterilized and non-sterilized Peruibe Black Mud in patients with knee osteoarthritis. International Journal of Environmental Research and Public Health, v. 18, n. 4, p. 1-11, 2021. DOI: 10.3390/ijerph18041666. Disponível em: http://repositorio.ipen.br/handle/123456789/32018. Acesso em: 26 Apr 2024.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.