SIMONE MICHAELA SIMONS
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Resumo IPEN-doc 21414 NAA application for multi-elemental analysis of Lonomia obliqua (Lepidoptera, Saturniidae) caterpillar2015 - SILVA, DALTON G.N. da; ZAMBONI, CIBELE B.; WEN, FAN H.; MEDEIROS, JOSE A.G. de; MENDONCA, RONALDO Z.; SIMONS, SIMONE M.Resumo IPEN-doc 19787 Investigation of inorganic elements in saliva from Amblyomma cajannense species from Brazil by the EDXRF technique2013 - SATO, IVONE M.; ZAMBONI, CIBELE B.; OLIVEIRA, DANIELLA G.L.; CHUDZINSKI-TAVASSI, ANA M.; SIMONS, SIMONE M.Artigo IPEN-doc 16956 Analyses of hemolymph from Amblyomma cajennense (Acari: ixodidae) using NAA2011 - SIMONS, SIMONE M.; OLIVEIRA, DANIELLA G.L.; CHUDZINSKI-TAVASSI, ANA M.; ZAMBONI, CIBELE B.Artigo IPEN-doc 16101 Immobilized kidney 28 KDa endostatin-related (KES28KDa) fragment promotes endothelial cell survival2010 - BELLINI, MARIA H.; MALPIGHI, THIAGO F.; CALVO, FERNANDA B.; MIRANDA, ADRIANA R.; SPENCER, PATRICK J.; CICHY, MILENA C.; SIMONS, SIMONE M.; TAVASSI, ANA M.C.; SANTOS, MARINILCE F. dos; RODRIGUES, CONSUELO J.; SCHOR, NESTORArtigo IPEN-doc 18035 Pro-apoptotic effects of amblyomin-X in murine renal cell carcinoma 'in-vitro'2012 - AKAGI, ERICA M.; SA JUNIOR, PAULO L. de; SIMONS, SIMONE M.; BELLINI, MARIA H.; BARRETO, SANDRA A.; CHUDZINSKI-TAVASSI, ANA M.Renal cell carcinoma (RCC) is one of the most lethal urologic cancers and is highly resistant to both radiotherapy and chemotherapy. The recombinant protein Amblyomin-X, characterized as a Kunitz-type protease inhibitor, was obtained from a cDNA library from the salivary glands of the Amblyomma cajennense tick. This paper reports the biological effect of Amblyomin-X on inducing cell death by apoptotic process in vitro. For this purpose, the changes in morphological aspects of cells, the phosphatidylserine exposition and DNA degradation were evaluated after treatment with Amblyomin- X. We found that Amblyomin-X was able to induce apoptosis in Renca cells in a dose-dependent manner. So, the results presented here open perspectives for new researches and developing for Amblyomin-X in the treatment of RCC.Artigo IPEN-doc 18056 Analysis of saliva from Amblyomma cajennense (Acari:Ixodidae) species from Brazil by NAA2012 - OLIVEIRA, DANIELLA G.L.; SIMONS, SIMONE M.; CHUDZINSKI-TAVASSI, A.M.; ZAMBONI, CIBELE B.Artigo IPEN-doc 18066 Determination of elements in blood of white New Zealand rabbits by NAA2012 - ZAMBONI, CIBELE B.; METAIRON, SABRINA; OLIVEIRA, LAURA C.; SIMONS, SIMONE M.; CHUDZINSKI-TAVASSI, A.M.; OLIVEIRA, DANIELLA G.L.