MARCELO NORONHA VELOSO
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Artigo IPEN-doc 29344 Bone as a biomarker for detecting low dose of ionizing radiation2022 - CASTRO, PEDRO A.A. de; DIAS, DERLY A.; VELOSO, MARCELO N.; ZEZELL, DENISE M.FTIR spectroscopy was able to discriminate bone samples receiving low-dose ionizing radiation doses (0.002 kGy, 0.004 kGy, 0.007 kGy), offering valuable insights in view of the understanding of radiation dose response in biological systems.Artigo IPEN-doc 28871 Assessment of bone dose response using ATR-FTIR spectroscopy2022 - CASTRO, PEDRO A.A. de; DIAS, DERLY A.; DEL-VALLE, MATHEUS; VELOSO, MARCELO N.; SOMESSARI, ELIZABETH S.R.; ZEZELL, DENISE M.The health care application of ionizing radiation has expanded worldwide during the last several decades. While the health impacts of ionizing radiation improved patient care, inaccurate handling of radiation technology is more prone to potential health risks. Therefore, the present study characterizes the bone dose response using bovine femurs from a slaughterhouse. The gamma irradiation was designed into low-doses (0.002, 0.004 and 0.007 kGy) and high-doses (1, 10, 15, 25, 35, 50 and 60 kGy), all samples received independent doses. The combination of FTIR spectroscopy and PLS-DA allows the detection of differences in the control group and the ionizing dose, as well as distinguishing between high and low radiation doses. In this way, our findings contribute to future studies of the dose response to track ionizing radiation effects on biological systems.Resumo IPEN-doc 24937 Biochemical evaluation of bone submitted to ionizing radiation by ATR-FTIR spectroscopy2017 - CASTRO, PEDRO A.A. de; DIAS, DERLY A.; VELOSO, MARCELO N.; ZEZELL, DENISE M.FTIR spectroscopy associated with PC-LDA was able to discriminate bone samples receiving different ionizing radiation doses (0,01 kGy, 1 kGy, 15 kGy), showing potential to the use of phosphate vibrational modes as a dose marker. OCIS codes: (170.4580) Medical optics and biotechnology – Optical diagnostics for medicine; (170.6510) Medical optics and biotechnology – Spectroscopy, tissue diagnostics; (170.1580) Medical optics and biotechnology – Chemometrics.Resumo IPEN-doc 21540 Estudo in vitro dos efeitos da radiação ionizante em tecidos ósseos por espectroscopia vibracional2015 - DIAS, DERLY A.; CASTRO, PEDRO A.A. de; LIMA, CASSIO; VELOSO, MARCELO N.; ZEZELL, DENISE M.Artigo IPEN-doc 21289 FTIR spectroscopy revealing the effects of laser and ionizing radiation on biological hard tissues2015 - ZEZELL, DENISE M.; BENETTI, CAROLINA; VELOSO, MARCELO N.; CASTRO, PEDRO A.A.; ANA, PATRICIA A.Artigo IPEN-doc 20969 Biochemical evaluation of bone submitted to ionizing radiation using ATR-FTIR spectroscopy associated to cluster analysis2015 - DIAS, DERLY A.; VELOSO, MARCELO N.; CASTRO, PEDRO A.A. de; LIMA, CASSIO A.; ZEZELL, DENISE M.Artigo IPEN-doc 20858 In vitro evaluation of ionizing radiation effects in bone tissue by FTIR spectroscopy2015 - ZEZELL, DENISE M.; VELOSO, MARCELO N.; DIAS, DERLY A.; POLITANO, RODOLFO; BENETTI, CAROLINAResumo IPEN-doc 17671 In vitro study of Er,Cr:YSGG laser effects in bone tissue by ATR-FTIR spectroscopy2011 - BENETTI, CAROLINA; VELOSO, MARCELO N.; ZEZELL, DENISE M.Artigo IPEN-doc 19309 Evaluation of ionizing radiation effects in bone tissue by FTIR spectroscopy and dynamic mechanical analysis2013 - VELOSO, MARCELO N.; SANTIN, STEFANY P.; BENETTI, CAROLINA; PEREIRA, THIAGO M.; MATTOR, MONICA B.; POLITANO, RODOLFO; ZEZELL, DENISE M.Artigo IPEN-doc 19478 Comparison between optical coherence tomography technique and mechanical compression assay to evaluate ionizing radiation effects in frozen and lyophilized bone tissue2013 - SANTIN, STEFANY P.; SANTOS, LUIZ A.U.; FREITAS, ANDERSON Z. de; MARTINHO JUNIOR, ANTONIO C.; DIAS, DJALMA B.; SOARES, FERNANDO A.N.; SEGURA PINO, EDDY; VELOSO, MARCELO N.; MATHOR, MONICA B.