VANESSA SILVA GRANADEIRO GARCIA

VANESSA SILVA GRANADEIRO GARCIA

Página do item completo

Resultados de Busca

Agora exibindo 1 - 10 de 10

Acute toxicity assessment of fluoxetine hydrochloride (Prozac®) when submitted to electron beam irradiation
2011 - SANTOS, D.R.A.; GARCIA, V.S.G.; VILARRUBIA, A.C.S.; BORRELY, S.I.
The large-scale production of medicinal products is directly related to the presence of pharmaceutical drugs in sewage and water. The continuous input of medicines and its residues into the environment especially by sewage and wastewater generates an increasing need of new methods for its treatment and suitable control. The fluoxetine hydrochloride (FH), also known as Prozac®, is an active ingredient used in the treatment of depressive and anxiety disorders [1]. The present study focused on applying the ionizing radiation in order to reduce the acute toxicity of the FH drug solution, under its manipulated formula, to aquatic organisms. Hyalella azteca and Daphnia similis were the organisms used in the biological assays applied for the toxicity studies. It was used a Dynamitron electron beam accelerator and its energy was fixed at 1,4MeV for 5kGy and 10kGy doses [2]. For the calculation of the effective concentration (EC50) it was used the statistic program Trimmed Spearman - Karber. The average values for acute toxicity of FH were 0.59mg.L-1 (EC5 096h) for Hyalella azteca and of 1,44mg.L-1 (EC5 048h) for Daphnia similis. After irradiation of the FH aqueous solution, the following EC50 average values were obtained: 7.81mg.L-1 (5kGy) and 7.97mg.L-1 (10kGy) for Hyalella azteca; 8,46mg.L-1 (5kGy ) and 7.31mg.L-1 (10kGy ) for Daphnia similis. The obtained results revealed the FH as a very toxic compound. These results are confirmed by the EU - Directive 93/67/EEC (Commission of the European Communities) [3]. A significant reduction of the acute effects was obtained when 5kGy and 10kGy were applied.
Toxicity and color reduction of reactive dyestuff RB 21 and surfactant submitted to electron beam irradiation
2021 - MELO, C.G.; ROSA, J.M.; GARCIA, V.S.G.; BORRELY, S.I.; PEREIRA, M.C.C.
There is an unwelcome reaction between the coloring and the water during the dyeing procedure, a portion of the coloring agent is lost in the bathing and it will compose the final whole effluent. The high absorbance index is related to lost dyestuffs and they also contribute with the toxic effects to the aquatic biota. In addition, these effluents contain large quantity of surfactants applied during dyeing baths, which also contribute to the high toxicity in these samples. The objective of this study was to evaluate electron beam irradiation technology, applied in samples of the Color Index Reactive Blue 21 (RB 21) dyestuff and in samples of surfactant non-ionic and in order to reduce toxicity for both and for RB 21, color reduction. Among the objectives of the study there are the dyestuff exhaustion degree, and some physical-chemical parameters. The acute toxicity assays were carried with Daphnia similis microcrustacean and the results of the dyestuff solution were: the irradiated samples with concentration 0.61 g L-1 did not present significant results, the EC 50 (%) value was to 58.26 for irradiated sample with 2.5 kGy and EC 50 (%) 63.59 for sample irradiated with 5 kGy. The surfactant was more toxic than RB 21, with EC 50 (%) value at 0.42. The color reduction reached 63.30% for the sample of the lowest concentration of effluent. There was a reduction of pH during irradiation.
Emprego de acelerador de elétrons para a redução da toxicidade de efluente têxtil e de produtos químicos aplicados durante o tingimento do algodão
2020 - GARCIA, VANESSA S.G.
O processo de beneficiamento têxtil utiliza importante quantidade de água durante a produção, enquanto gera efluentes que possuem diversos tipos de compostos químicos, como: surfactantes, peróxidos, ácidos, sais e corantes. Devido a sua complexidade, comumente estes efluentes possuem elevada carga tóxica e coloração. Os Processos Oxidativos Avançados vêm sendo utilizados para melhorar a tratabilidade desse tipo de efluente, complementando o tratamento biológico. A irradiação com feixes de elétrons tem sido proposta como tecnologia para tratamento de efluentes têxteis, auxiliando na redução da toxicidade, coloração, demanda química de oxigênio, entre outros parâmetros. Os principais objetivos deste trabalho foram: avaliar a toxicidade de compostos químicos utilizados no beneficiamento das fibras de algodão, além do efluente final (contendo corante reativo Red 239) em organismos aquáticos; e avaliar a eficiência da irradiação por feixe de elétrons no tratamento destes contaminantes. Os ensaios de toxicidade para efeito agudo foram realizados com organismos aquáticos: bactéria Vibrio fischeri e o crustáceo Daphnia similis. Este último também foi empregado para avaliar efeito crônico: reprodução, efeitos subletais e comprimento córporeo, pela exposição de 21 dias ao efluente têxtil contendo o corante reativo Red 239. O efluente, bem como os compostos orgânicos, foram submetidos à irradiação em acelerador de elétrons, com variação de dose de radiação entre 0,5 e 15 kGy. O tratamento com irradiação reduziu a toxicidade, a coloração, a demanda química de oxigênio e o carbono orgânico total do efluente. Em relação à toxicidade aguda, para o efluente bruto os valores médios de CE 50% ficaram entre 2,93 ± 0,13 e 9,28 ± 0,32 para D. similis e 5,65 ± 0,16 e 8,40 ± 1,45 para V. fischeri. O tratatamento com feixe de elétrons foi efetivo na redução da toxicidade das amostras de efluente, sendo obtidos os seguintes valores com 5 kGy: CE50% = 16,36 ± 5,37, representando 61,43% de remoção de toxicidade para D. similis e 15,05 ± 2,93, remoção de toxicidade de 50,73% para V. fischeri. Enquanto 10 kGy resultou em mais de 70% de remoção de efeitos agudos para ambos os organismos expostos. Com relação à redução de cor, 5 kGy resultou em eficiência superior a 95%. Dentre os surfactantes analisados, os não-iônico, óxido de alquileno e o etoxilado, foram os mais tóxicos para ambos os organismos, com valores médios de CE 50 inferiores a 4,5 mg L-1. Em relação à exposição crônica de D. similis ao efluente têxtil bruto (concentração 3%) foram observados efeitos subletais, como deposição de corante no sistema filtrador e má formação de ovos.
Toxicity and color reduction of a textile effluent containing reactive red 239 dye by electron beam irradiation
2020 - GARCIA, VANESSA S.G.; ROSA, JORGE M.; BORRELY, SUELI I.
Textile effluents are a mixture of dyestuff, surfactants, dispersants, acids, alkalis and bleaching agents, among other compounds, and some of these are highly soluble and relatively recalcitrant. Suitable improvement of textile effluents may require combined treatment processes, such as Conventional Treatments and Advanced Oxidative Process (AOPs). Electron beam irradiation (EBI) has been proposed as a possible technology for the treatment of textile effluents. In this context, the aim of the present study was to evaluate the efficiency of an Electron Beam treatment applied to toxicity and color reduction of a textile effluent containing reactive Red 239 dye. Effluent COD and TOC were also evaluated. The assessed effluents were submitted to EBI treatment at doses ranging from 0.5 to 15 kGy. Vibrio fischeri bacteria and Daphnia similis crustaceans were exposed to both irradiated and non-irradiated effluents, the toxicity was evaluated through EC50 (median effective concentration) calculations. EB irradiation successfully reduced effluent toxicity and color. The EC50 for D. similis(48h) were of 6.31% ± 3.19 (non-irradiated) and 27.56% ± 9.31 (10 kGy), and for V. fischeri(15min), of 7.41% ± 1.52 (nonirradiated) and 31.89% ± 10.99 (10 kGy), respectively. Approximately 70% toxicity reduction was obtained for both organisms, while 95% color reduction was obtained by applying 5 kGy.
Electron beam irradiation of pharmaceuticals aiming at toxicity reduction
2019 - BOIANI, N.F.; SILVA, V.H.O.; GARCIA, V.S.G.; DEL SOLE, S.V.; BORRELY, S.I.
Significant evidence is available in the literature justifying the search for treatment technologies or process combinations to improve the decomposition of dozens of pharmaceuticals in wastewater. Conventional processing techniques are insufficient in removal of the pharmaceuticals, for having resistant waste and low biodegradability. Electron beam irradiation (EBI) may play an important role in this context, and relatively low doses have been reported for such purposes. The objective of this study was to apply the process of irradiation with electron beam in order to reduce the toxic effects of fluoxetine, propranolol, and a binary mixture of these pharmaceuticals in aqueous solution. Ecotoxicological tests conducted in two model organisms, Daphnia similis microcrustacean, and Vibrio fischeri bacterium. It was observed that D. similis was more sensitive to the pharmaceuticals and binary mixture, when compared to V. fischeri. When EBI was applied, all doses showed significant reduction of toxicity for D. similis, and the opposite for V. fischeri, when only 5.0 kGy showed a significant reduced of toxicity for the pharmaceuticals and binary mixture. 5.0 kGy was the best removal efficiency for toxicity, approximately 80% for D. similis and 20% for V. fischeri.
Toxicity and color reduction of reactive dyestuff RB21 and surfactant submitted to electron beam irradiation
2019 - MELO, CAMILA G.; ROSA, JORGE M.; GARCIA, VANESSA S.G.; BORRELY, SUELI I.; PEREIRA, MARIA da C.C.
There is an unwelcome reaction between the coloring and the water during the dyeing procedure, a portion of the coloring agent is lost in the bathing and it will compose the final whole effluent. The high absorbance index is related to lost dyes and they also contribute with the toxic effects to the aquatic biota. In addition, these effluents contain large quantity of surfactants applied during dyeing baths, which also contribute to the high toxicity in these samples. The objective of this study was to evaluate electron beam irradiation technology, applied in samples of the Color Index Reactive Blue 21 (RB21) dye and in samples of surfactant nonionic and in order to reduce toxicity for both and for RB21, color reduction. Among the objectives of the study there are the dye exhaustion degree, and some physic-chemical parameters. The acute toxicity assays were carried with Daphnia similis microcrustacean and the results for of dyestuff solution were: the irradiated samples with concentration of 0.61g.L-1 did not present significant results, the EC 50(%) value was to 58.26 for irradiated sample with 2.5kGy and EC 50(%) 63.59 for sample irradiated with 5kGy. The surfactant was more toxic than RB 21, with EC 50(%) value at 0.42. The color reduction reached 63.30% for the sample of the lowest concentration of effluent. There was a reduction of pH during irradiation.
Toxicity of textile effluents treated by electron beam technology
2019 - GARCIA, VANESSA S.G.; BOIANI, NATHALIA F.; ROSA, JORGE M; BORRELY, SUELI I.
The textile industry uses expressive amount of water during the production and generate effluents that contain residuals of dyes, surfactants, peroxides, acids and salts, and toxicity. In addition, the textile effluents are commonly colored, because the dyes used in fibers dyeing usually have low fixation and high solubility. Many of the mentioned products are not easily removed, requiring additional treatment steps. Advanced Oxidative Processes, such as electron beam irradiantion (EBI), can be a good alternative to reduction of organic pollutants from effluents. Therefore, studies on these contaminants in aquatic environment are important for assessing their impacts on ecosystems and water quality. The objective of this study was to evaluate the toxicity of textile effluents treated with EBI. The doses of 2.5 kGy and 5.0 kGy were used. The toxicity assays were performed with Daphnia similis organisms, exposed to samples during 48 hours, and the results expressed by EC50 (median effective concentration). For the textile effluent, EC 50% values ranged from: 2.95 ±0.13 (raw effluent) until 20.90 ±1.48 (irradiated effluent, at 5kGy). The EBI treatment was effective for toxicity reduction, with efficiency higher than 60% (2.5 kGy) and 80% (5.0 kGy). The study of organic and inorganic contaminants, presents in these effluents, demonstred EC 50 values below 5%. These results demonstrate high toxicity of contaminants from textile effluents for aquatic organisms (D. similis, cladocera). Similar data was observed for the raw effluent. These values are relevant for thinking radiation as a possible technology for such a type of effluent.
Electron beam irradiation of combined pharmaceuticals
2019 - BOIANI, NATHALIA F.; VILLARDI, BRUNO D.Q.; GARCIA, VANESSA S.G.; BORRELY, SUELI I.
There are serious evidences that justify the search for treatment technologies or processes combination for the improvement of decomposition for dozens of pharmaceuticals in wastewaters. Electron beam irradiation may play an important role in this scenario and relatively low doses have been reported for such purposes. The aim of the present study was to evaluate the toxic response of the crustacean Daphnia similis exposed to individual and combined pharmaceuticals. Several experimental trials of an acute immobilization test were performed with a mixture of pharmaceuticals composed of fluoxetine hydrochloride (Prozac®), and propranolol. Single pharmaceuticals were first tested separately. Toxicity of binary mixture was then assessed using five concentrations and 5 percentages of each substance in the mixture (0, 25, 50, 75, and 100%). Acute EC50% values ranged from 5.0 to 7.4 for fluoxetine and from 11.3 to 13.7 for propranolol. In mixture, values ranged from 6.4 to 9.8. Fluoxetine was more toxic for D.similis than propranolol. The different pharmaceuticals concentrations employed in a mixture showed no difference in toxicity values. When electron beam irradiation was applied, approximately 80% of acute effects were reduced at 5 kGy, and the mixture containing a higher percentage of fluoxetine, also showed a greater reduction of toxicity.
Electron beam irradiation of textile effluents and non-ionic ethoxylated surfactant for toxicity and color removal
2019 - BORRELY, S.I.; SILVA, L.G.A.; DEL SOLE, S.V.; GARCIA, V.S.G.; BOIANI, N.F.; ROSA, J.M.
Textile industry has an expressive scenario in the world economy and Brazil is the 5th in the textile production. By 2015, Brazilian textile production represented US $ 39.3 billion, accounting for more than 1.8 million tons of fabric. The effluents from textile industry are highlighted by quantity of wastewater discharged and variety of substances (dyes, bleaching agents, surfactants, salts, acids, among others). Such compounds often prove to be toxic to aquatic biota. This present study aims to assess toxicity of whole effluents, before and after irradiation (by electron beam accelerator, EBI). In addition, the reduction of the effluent color after irradiation is also very important. Daphnia similis and Vibrio fischeri were the biological systems applied for toxicity evaluations. Previous results demonstrated the surfactant as the main toxic compound, in the untreated and irradiated forms, EC 50 = 0.44 ppm ± 0.02 (untreated); EC 50 = 0.46 % ± 0.07 (irradiated). The irradiation was effective for reducing color of the effluent, starting from 0.5 kGy. EB irradiation may be proposed as an alternative treatment for the final effluent from textile processing, mainly for reuse purposes.
Electron beam irradiation of textile effluents and non-ionic ethoxylated surfactant for toxicity and color removal
2017 - SOLE, STEPHANIE V. DEL; GARCIA, VANESSA S.G.; BOIANI, NATHALIA F.; ROSA, JORGE M.; SILVA, LEONARDO G. de A. e; BORRELY, SUELI I.
Textile industry has an expressive scenario in the world economy and Brazil is the 5th in the textile production. By 2015, Brazilian textile production represented US $ 39.3 billion, accounting for more than 1.8 million tons of fabric (ABIT, 2017). The effluents from textile industry are highlighted by quantity of wastewater discharged and variety of substances (dyes, bleaching agents, surfactants, salts, acids, among others). Such compounds often prove to be toxic to aquatic biota. This present study aims to assess toxicity of whole effluents, before and after irradiation (by electron beam accelerator, EBI). In addition, the reduction of the effluent color after irradiation is also very important. Daphnia similis and Vibrio fischeri were the biological systems applied for toxicity evaluations. Previous results demonstrated the surfactant as the main toxic compound, in the untreated and irradiated forms, EC 50 = 0.44 ppm ± 0.02 (untreated); EC 50 = 0.46 % ± 0.07 (irradiated). The irradiation was effective in reducing the color of the effluent, starting from 0.5 kGy. EB radiation may be proposed as an alternative treatment for the final effluent from textile processing, mainly for reuse purposes.