Whole blood differences of inorganic elements in dystrophic animal models
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2016
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REUNIÃO DE TRABALHO SOBRE FÍSICA NUCLEAR NO BRASIL, 39.
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The Duchenne Muscular Dystrophy (DMD) disease is characterized by presenting an irreversible
progressive degeneration of skeletal muscle. Currently, no effective treatment is available and the
DMD research progress depends on animal models. In order to evidence in more details the
alterations that DMD disease may cause in blood a comparison of inorganic elements between two
animal models (mouse and dog) with muscular dystrophy were made. The dystrophic models were
obtained from different research centers at São Paulo city. Several inorganic elements of clinical
and nutritional relevance were investigated using Neutron Activation Analysis (NAA). These
measurements were performed in the nuclear reactor IEA-R1 (3.5- 4.5MW, pool type) at
IPEN/CNEN-SP, Brazil. The knowledge of the elemental composition in these animal models may
also help to identify the physiologic difference among them. Moreover, these data can be useful
for biochemistry analyses contributing for studying in more details the anomalies caused by DMD.
Como referenciar
METAIRON, S.; ZAMBONI, C.B.; SUZUKI, M.F. Whole blood differences of inorganic elements in dystrophic animal models. In: REUNIÃO DE TRABALHO SOBRE FÍSICA NUCLEAR NO BRASIL, 39., 03-07 de setembro, 2016, Natal, RN. Abstract... Disponível em: http://repositorio.ipen.br/handle/123456789/27606. Acesso em: 23 May 2024.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.