Broadband radiometry for photodynamic therapy
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2010
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BIOPHOTONICS: PHOTONIC SOLUTIONS FOR BETTER HEALTH CARE II
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Resumo
The effective irradiance is a useful measure to compare performances of different broadband light sources and to more
precisely predict the outcome of a topical photodynamic therapy. The effective irradiance (or effective fluence rate) and
the exposition time of the optical radiation usually determine the light dose. The effective irradiance (Eeff) takes into
account the spectral irradiance of the source as well as the action spectrum, where the wavelength dependence of both
optical diffusion through tissue and photosensitizer are considered. In practice there are no standard action spectra for the
currently used photosensitizers. As a consequence, measured values of effective irradiance using different action spectra
can not be compared. In order to solve this problem, the basis of the calibration theory developed for the broadband
ultraviolet radiometry can be applied, where an experimental radiometer is compared with a standard radiometer. Here
is presented a simple set of linear relations in the form Eeff = k . E, where E is the source irradiance and k a real positive
value, here denoted as a characteristic of the radiometer, as valuable tools for correction of effective irradiances
measured according to different action spectra. As a result, for two effective radiometers with different characteristics k1
and k2, measured values are Eeff and Qeff respectively, and it is easily shown that the value 1 2 E Q k k eff eff = ⋅ .
Como referenciar
FOLGOSI-CORREA, M.S.; CALY, J.P.; NOGUEIRA, G.E.C. Broadband radiometry for photodynamic therapy. In: POPP, JURGEN (ed.); DREXLER, WOLFGANG (ed.); TUCHIN, VALERY V. (ed.); MATTHEWS, DENNIS L. (ed.). In: BIOPHOTONICS: PHOTONIC SOLUTIONS FOR BETTER HEALTH CARE II, April 12, 2010, Brussels, Belgium. Proceedings... (SPIE Proceedings Series, 7715). Disponível em: http://repositorio.ipen.br/handle/123456789/26674. Acesso em: 19 Feb 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.