Chemometric evaluation of ampicillin stability using FTIR spectroscopy and multivariate techniques

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dc.contributor.authorANJOS, VINICIUS P.
dc.contributor.authorFREIRE, MARIA R.V.B.
dc.contributor.authorSTASI, RAFFAELE
dc.contributor.authorSILVA, DANIELA de F.T. da
dc.contributor.authorZEZELL, DENISE M.
dc.coverageInternacional
dc.creator.eventoSBFoton International Optics and Photonics Conference (SBFoton IOPC)
dc.date.accessioned2026-03-02T19:08:07Z
dc.date.available2026-03-02T19:08:07Z
dc.date.eventoSeptember 21-24, 2025
dc.description.abstractAntibiotic quality has always been a concern in the pharmaceutical industry and the World Health Organization (WHO), especially in the growing and emerging antimicrobial resistance crisis. FTIR spectroscopy can contribute to the monitoring of antimicrobials, especially when coupled with chemometric techniques. The present work aims to investigate spectral differences of Ampicillin samples through FTIR qualitatively and quantitatively, highlighting the spectral differences associated with different degradation conditions (acidic and thermal).
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Ensino Superior (CAPES)
dc.description.sponsorshipIDCNPq: 406761/2022-1; Sisfoton 440228/2021-2; PQ: 314517/2021-9
dc.description.sponsorshipIDFAPESP: 21/00633-0, 20/07065-4, 25/03135-1
dc.description.sponsorshipIDCAPES: 001
dc.event.siglaSBFoton IOPC
dc.identifier.citationANJOS, VINICIUS P.; FREIRE, MARIA R.V.B.; STASI, RAFFAELE; SILVA, DANIELA de F.T. da; ZEZELL, DENISE M. Chemometric evaluation of ampicillin stability using FTIR spectroscopy and multivariate techniques. In: SBFoton International Optics and Photonics Conference (SBFoton IOPC), September 21-24, 2025, São Pedro, SP. <b>Proceedings...</b> Piscataway, Nova Jersey: IEEE, 2025. DOI: <a href="https://dx.doi.org/10.1109/SBFotonIOPC66433.2025.11218464">10.1109/SBFotonIOPC66433.2025.11218464</a>. Disponível em: https://repositorio.ipen.br/handle/123456789/49388.
dc.identifier.doi10.1109/SBFotonIOPC66433.2025.11218464
dc.identifier.orcidhttps://orcid.org/0000-0001-7404-9606
dc.identifier.urihttps://repositorio.ipen.br/handle/123456789/49388
dc.language.isoeng
dc.localPiscataway, Nova Jersey
dc.local.eventoSão Pedro, SP
dc.publisherIEEE
dc.rightsopenAccess
dc.titleChemometric evaluation of ampicillin stability using FTIR spectroscopy and multivariate techniques
dc.typeTexto completo de evento
dspace.entity.typePublication
ipen.autorVINICIUS PEREIRA DOS ANJOS
ipen.autorMARIA RENATA VALENTE BRANDAO FREIRE
ipen.autorRAFFAELE STASI
ipen.autorDANIELA DE FATIMA TEIXEIRA DA SILVA
ipen.autorDENISE MARIA ZEZELL
ipen.codigoautor16182
ipen.codigoautor14078
ipen.codigoautor16200
ipen.codigoautor2524
ipen.codigoautor693
ipen.contributor.ipenauthorVINICIUS PEREIRA DOS ANJOS
ipen.contributor.ipenauthorMARIA RENATA VALENTE BRANDAO FREIRE
ipen.contributor.ipenauthorRAFFAELE STASI
ipen.contributor.ipenauthorDANIELA DE FATIMA TEIXEIRA DA SILVA
ipen.contributor.ipenauthorDENISE MARIA ZEZELL
ipen.event.datapadronizada2025
ipen.identifier.ipendoc31496
ipen.notas.internasProceedings
ipen.type.genreArtigo
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sigepi.autor.atividadeVINICIUS PEREIRA DOS ANJOS:16182:-1:N
sigepi.autor.atividadeMARIA RENATA VALENTE BRANDAO FREIRE:14078:110:N
sigepi.autor.atividadeRAFFAELE STASI:16200:-1:N
sigepi.autor.atividadeDANIELA DE FATIMA TEIXEIRA DA SILVA:2524:920:N
sigepi.autor.atividadeDENISE MARIA ZEZELL:693:920:N

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