Effects of low intensity laser radiation in the prevention of oral mucositis in patients undergoing bone marrow transplant
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Brazilian Dental Journal
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Oral mucositis is one of the complications arising from pre bone marrow
transplant conditioning, which can substantially change the patient's quality
of life. The purpose of this randomized double blind study was to compare
the effects of low intensity laser radiation in the prevention of oral
mucositis in patients undergoing bone marrow transplants. Seventy
patients at the Seattle Cancer Care Alliance in the U.S.A. were approved
by the local ethics committee and gave their informed consent to take part
in the study. The 70 patients were divided into three groups (group 1 -
laser 650nm; group 2 - laser 780nm and group 3 placebo). The therapy or
placebo treatment began on the first day of the conditioning and continued
through to two days following the bone marrow transplant. Mucositis
was measured according to the oral mucositis rate and the pain assessment
rate (VAS). We were thus able to conclude that the diode 650nm
laser indeed decreased the severity of oral mucositis as well as the degree
the pain when used as a preventative therapy in patients undergoing bone
marrow transplants. In this study, low intensity laser therapy was regarded
as safe and did not present any side effects.
Como referenciar
EDUARDO, F.P.; NICOLLI FILHO, W.; MIGLIORATI, C.A.; ZEZELL, D.M.; EDUARDO, C.P.; SCHUBERT, M.M. Effects of low intensity laser radiation in the prevention of oral mucositis in patients undergoing bone marrow transplant. Brazilian Dental Journal, v. 15, p. 97-97, 2004. Special issue. Disponível em: http://repositorio.ipen.br/handle/123456789/32744. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.