Quality control in the production of radiopharmaceuticals
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Resumo
Radiopharmaceuticals are central to nuclear medicine applications for the diagnosis and therapy
of human diseases, especially cancers and cardiovascular diseases. In the past few decades,
advances in the production and quality control of emerging radiopharmaceuticals have led to
the production of new radiopharmaceuticals and the availability of new production routes and
methods for existing agents. Various new diagnostic agents in the field (such as 68Ga
radiopharmaceuticals and generators) as well as therapeutic agents (such as alpha emitters) have
already been added to the clinician toolkit. However, the lack of generic and peer-reviewed
quality control guidelines and recommendations for their application in human patients is a
major concern.
To address this need, and in response to requests from Member States and professional
societies, the IAEA developed this publication on quality control in the production of
radiopharmaceuticals. It is expected to be of use for all professionals involved in the production
and quality control of radiopharmaceuticals worldwide.
This publication is an outcome of the work of an international team of experts in the field
between 2016 and 2018. The IAEA wishes to thank the experts for their contributions. Special
thanks are due to J. Ballinger (United Kingdom) for compiling the material, and
J.S. Vera Araujo (Bolivarian Republic of Venezuela) for her editorial support. The IAEA
officer responsible for this publication was A.R. Jalilian of the Division of Physical and
Chemical Sciences.
Como referenciar
FUKUMORI, N. Quality control in the production of radiopharmaceuticals. In: INTERNATIONAL ATOMIC ENERGY AGENCY (ed.); BALLINGER, J. (colab.); BRUCHERTSEIFER, F. (colab.); DOLLÉ, F. (colab.); FUKUMORI, N. (colab.); JALILIAN, A. (colab.); KRASIKOVA, R. (colab.); KVATERNIK, H. (colab.); LYASHCHENKO, S. (colab.); OCAK, M. (colab.); OSSO, J. (colab.); PANDEY, U. (colab.); SEIMBILLE, Y. (colab.); TODDE, S. (colab.). Vienna: International Atomic Energy Agency, 2018. 150p. pt. (IAEA TECDOC series, 1856). Disponível em: http://repositorio.ipen.br/handle/123456789/29239. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.