Comparing two Monte Carlo codes to simulate the ideal activity of a phosphorus-32 film source using dose rate obtained by clinical applications
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Physica Medica - European Journal of Medical Physics
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Introduction: Phosphorus-32 encapsulated in a polymeric base is a
promising source for brachytherapy, especially for intracavitary
brachytherapy (IBT) [1, 2]. From the clinical studies published, a good
dose rate for this source to have is 1 Gy/min [3, 4, 5]. A similar source
has been developed with a new formulation. In this work, two Monte
Carlo codes were compared to evaluate the ideal activity this source
must have to deliver a 1 Gy/min dose rate.
Materials & Methods: TOPAS 3.8 [6] and MCNP6.2 [7] were used to
model two simulations, both with the source centered in the origin
point, above an isotropic volume of water 1 mm deep (2.5 cm³). The
source has the decay properties of phosphorus-32, whose beta
emission spectrum was extracted from the IAEA website. For TOPAS,
EnergyDeposit scoring was used, and tally*F8 for MCNP. Dividing dose
per decay by the dose rate of 1 Gy/min, the simulated source’s total
activity can be obtained.
Results: Table 1 shows the results for both simulations. Therefore, the
source’s initial activity must be between 2.13 × 109 Bq (57.44 mCi) and
2.19 × 109 Bq (59.06 mCi) to obtain the 1 Gy/min dose rate.With only a
2.8% difference between both codes’ results, it is safe to assume that the
simulations are reliable.
Summary: These results facilitate the source manufacturing, and, with
them, it is possible to minimize the patient’s exposure to radiation,
while ensuring the quality of the treatment.
Como referenciar
TEODORO, L.E.H.; BURIN, A.L.; TAVARES, P.V. dos S.; KOKA, A.C.; TALACIMON, C.F.; RIGO, M.E.Z.; MEDEIROS, I.M.M.A.; RODRIGUES, P.S.; SGRIGNOLI, S.S.; ROSA, G.M.; ANGELOCI, L.V.; SOUZA, C.D. de; RODRIGUES JUNIOR, O.; ZEITUNI, C.A.; ROSTELATO, M.E.C.M. Comparing two Monte Carlo codes to simulate the ideal activity of a phosphorus-32 film source using dose rate obtained by clinical applications. Physica Medica, v. 125, p. S424-S424, 2024. Suppl 1. DOI: 10.1016/j.ejmp.2024.104096. Disponível em: https://repositorio.ipen.br/handle/123456789/49750. Acesso em: 27 Apr 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.