Effect of gamma radiation on polyvinylpyrrolidone hydrogels

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dc.contributor.authorOLIVEIRA, M.J.A.
dc.contributor.authorVASQUEZ, P.A.S.
dc.contributor.authorALCANTARA, M.T.S.
dc.contributor.authorMUNHOZ, M.M.L.
dc.contributor.authorLUGAO, A.B.
dc.coverageInternacionalpt_BR
dc.creator.eventoINTERNATIONAL NUCLEAR ATLANTIC CONFERENCEpt_BR
dc.date.accessioned2018-01-17T15:36:11Z
dc.date.available2018-01-17T15:36:11Z
dc.date.eventoOctober 22-27, 2017pt_BR
dc.description.abstractPolyvinylpyrrolidone (PVP) hydrogels have been investigated as drug delivery matrices for the treatment of wounds, such as cutaneous leishmaniasis, and matrices with silver nanoparticles for chronic wounds and burns. The preparation of such hydrogels can occur by various cross-linking methods, such as gamma, chemical, physical, among others. The most feasible for wound dressings is gamma irradiation from cobalt-60, because gamma irradiation simultaneously promotes crosslinking and sterilization, leaving the wound dressing ready for use. The objective of this work was to investigate the effect on physico- chemical properties of gamma radiation on PVP hydrogel according to the radiation absorbed dose variation. The PVP hydrogels were irradiated with doses of 5, 15, 25, 35, 45, 55, 65, 75 and 95kGy at dose rate of 5 kGy/h and characterized by swelling, thermogravimetric and mechanical analysis. Results shown a favorable dose range window for processing of these hydrogels related to the application. The results showed that mechanical strength was affected at doses starting at 25 kGy.pt_BR
dc.event.siglaINACpt_BR
dc.identifier.citationOLIVEIRA, M.J.A.; VASQUEZ, P.A.S.; ALCANTARA, M.T.S.; MUNHOZ, M.M.L.; LUGAO, A.B. Effect of gamma radiation on polyvinylpyrrolidone hydrogels. In: INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE, October 22-27, 2017, Belo Horizonte, MG. <b>Proceedings...</b> Rio de Janeiro, RJ: Associação Brasileira de Energia Nuclear, 2017. Disponível em: http://repositorio.ipen.br/handle/123456789/28349.
dc.identifier.orcidhttps://orcid.org/0000-0002-1737-3191
dc.identifier.orcidhttp://orcid.org/0000-0003-4168-1626
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/28349
dc.localRio de Janeiro, RJpt_BR
dc.local.eventoBelo Horizonte, MGpt_BR
dc.publisherAssociação Brasileira de Energia Nuclearpt_BR
dc.rightsopenAccesspt_BR
dc.subjectabsorbed radiation doses
dc.subjectchemical properties
dc.subjectcobalt 60
dc.subjectdifferential thermal analysis
dc.subjectdose rates
dc.subjectfourier transformation
dc.subjectgamma radiation
dc.subjecthydrogels
dc.subjectinfrared spectra
dc.subjectphysical properties
dc.subjectpvp
dc.subjectradiation effects
dc.subjectswelling
dc.subjecttensile properties
dc.subjectthermal gravimetric analysis
dc.subjectwounds
dc.titleEffect of gamma radiation on polyvinylpyrrolidone hydrogelspt_BR
dc.typeTexto completo de eventopt_BR
dspace.entity.typePublication
ipen.autorMARA DE MELLO LEITE MUNHOZ
ipen.autorADEMAR BENEVOLO LUGAO
ipen.autorMARA TANIA SILVA ALCANTARA
ipen.autorPABLO ANTONIO VASQUEZ SALVADOR
ipen.autorMARIA JOSE ALVES DE OLIVEIRA
ipen.codigoautor8585
ipen.codigoautor339
ipen.codigoautor2295
ipen.codigoautor3075
ipen.codigoautor3310
ipen.contributor.ipenauthorMARA DE MELLO LEITE MUNHOZ
ipen.contributor.ipenauthorADEMAR BENEVOLO LUGAO
ipen.contributor.ipenauthorMARA TANIA SILVA ALCANTARA
ipen.contributor.ipenauthorPABLO ANTONIO VASQUEZ SALVADOR
ipen.contributor.ipenauthorMARIA JOSE ALVES DE OLIVEIRA
ipen.date.recebimento18-01pt_BR
ipen.event.datapadronizada2017pt_BR
ipen.identifier.ipendoc24184pt_BR
ipen.notas.internasProceedingspt_BR
ipen.type.genreArtigo
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relation.isAuthorOfPublication47e9cd5a-dfda-4392-a887-42617e3c280f
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relation.isAuthorOfPublication.latestForDiscoverydb19966e-6f74-43fc-84b1-c24c1d826e0c
sigepi.autor.atividadeOLIVEIRA, M.J.A.:3310:740:Spt_BR
sigepi.autor.atividadeVASQUEZ, P.A.S.:3075:240:Npt_BR
sigepi.autor.atividadeALCANTARA, M.T.S.:2295:740:Npt_BR
sigepi.autor.atividadeMUNHOZ, M.M.L.:8585:220:Npt_BR
sigepi.autor.atividadeLUGAO, A.B.:339:740:Npt_BR
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