Synthesis of hybrid AuFe nanoparticles by photoreduction and methyl aminoluvinate
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2018
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SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE
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The nanohybrid gold/iron (AuFe) system is
particularly interesting for biomedical applications such as
targeted drug delivery, hyperthermia and photodynamic
therapy (PDT) mainly due to its magnetic combined to the
plasmonic properties. In this study, we aimed to synthesize
nanohybrids to be used as a vehicle to deliver Methyl
Aminoluvinate (MAL) for selective and efficient PDT. MAL is
a prodrug that is metabolized to protoporphyrin IX (PpIX),
photosensitizer in PDT. The nanohybrids were synthesized by
photoreduction of solutions containing iron powder,
polyethylene glycol (PEG), chloroauric acid (HAuCl4) and
MAL as a reducing agent in water solution. The products were
characterized by UV-Vis, zeta potential and transmission
electron microscopy. The synthesized nanoparticles had the
optical properties of metallic nanoparticles and the magnetic
properties of iron nanoparticles. Their characteristic
absorption bands, in the visible light range, became become
broader and red‐shifted in the presence of iron nanoparticles.
Cell viability of cancer cell lines in the presence of nanohybrids
studies were performed.
Como referenciar
GONÇALVES, KARINA de O.; SILVA, FLAVIA R. de O.; VIEIRA, DANIEL P.; COURROL, LILIA C. Synthesis of hybrid AuFe nanoparticles by photoreduction and methyl aminoluvinate. In: SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE, October 08-10, 2018, Campinas, SP. Proceedings... Piscataway, NJ, USA: IEEE, 2018. DOI: 10.1109/SBFoton-IOPC.2018.8610950. Disponível em: http://repositorio.ipen.br/handle/123456789/30138. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.