Magnetic nanoparticles and their application in biomedicine
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2007
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INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE; MEETING ON NUCLEAR APPLICATIONS, 8th/ MEETING ON REACTOR PHYSICS AND THERMAL HYDRAULICS, 15th
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Resumo
The magnetic nanoparticles offer some attractive possibilities in biomedicine for the following reasons: First,
they have controllable sizes ranging from a few nanometers up to tens of nanometers, which places them at
dimensions that are smaller than or comparable to those of a cell (10–
–450 nm) or a protein
(5–50 nm). Second, the nanoparticles are magnetic, which means that they obey Coulomb’s law, and can be
manipulated by an external magnetic field gradient. This possibility, combined with the intrinsic penetrability of
magnetic fields into human tissue, opens up many applications involving the transport and/or immobilization of
magnetic nanoparticles, or of magnetically tagged biological entities. Third, the magnetic nanoparticles can be
made to resonantly respond to a time-varying magnetic field, with advantageous results related to the transfer of
energy from the exciting field to the nanoparticle. In this paper, we will address the underlying chemical and
physics of the biomedical applications of magnetic nanoparticles including radioisotope delivery and a magnetic
radiolabeled fluid. We will consider four particular applications: magnetic separation for radio labeled proteins,
drug radiolabeled delivery, hyperthermia treatments, and magnetic resonance imaging (MRI) contrast
enhancement. There will be included some results obtained in our laboratory in the obtention of these magnetic
nanoparticles.
Como referenciar
FELINTO, MARIA C.F.C.; CAMILO, RUTH L.; DIEGUES, T.G. Magnetic nanoparticles and their application in biomedicine. In: INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE; MEETING ON NUCLEAR APPLICATIONS, 8th/ MEETING ON REACTOR PHYSICS AND THERMAL HYDRAULICS, 15th, Sept. 30 - Oct. 5, 2007, Santos, SP. Proceedings... Disponível em: http://repositorio.ipen.br/handle/123456789/15715. Acesso em: 25 Mar 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.