Biocompósitos de nitreto de silício: caracterização e avaliação biológica in vitro

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dc.contributor.authorGUEDES-SILVA, C.C.
dc.contributor.authorRODAS, A.C.D.
dc.contributor.authorRIBEIRO, C.
dc.contributor.authorCARVALHO, F.M.S.
dc.contributor.authorGENOVA, L.A.
dc.contributor.authorFERREIRA, T.S.
dc.contributor.authorHIGA, O.Z.
dc.coverageNacionalpt_BR
dc.creator.eventoCONGRESSO BRASILEIRO DE CERAMICA, 60.pt_BR
dc.date.accessioned2016-12-19T12:24:07Z
dc.date.available2016-12-19T12:24:07Z
dc.date.evento15-18 de maio, 2016pt_BR
dc.description.abstractSilicon nitride has been increasingly considered for biomedical applications owing to their high mechanical properties, osseointegration, bactericidal capacity and radiolucent characteristics. This study aims to evaluate the potential of silicon nitride ceramics containing silica and calcia in appropriate concentrations to have a bioactive intergranular phase, formed by a bioglass without phosphorus. Samples with 20 wt.% additives were sintered at 1815oC for 1 h under N2 atmosphere and analyzed in regard to density, crystalline phases, morphology and grain size as well as phases' distribution. Biological assessments by means of bioactivity tests in SBF (Simulated Body Fluid), cytotoxicity and osteoblast adhesion of MG63 cell line were performed. The results showed that samples reached around 97% of the theoretical density, high αβ-Si3N4 transformation and bioactivity evidenced by apatite formation on samples surface after testing in SBF. Silicon nitride samples exhibited non-cytotoxic and biocompatible behavior for propagation of human bone cells in vitro, demonstrating the high potential to be used as prosthetic devices and components.pt_BR
dc.format.extent1782-1793pt_BR
dc.identifier.citationGUEDES-SILVA, C.C.; RODAS, A.C.D.; RIBEIRO, C.; CARVALHO, F.M.S.; GENOVA, L.A.; FERREIRA, T.S.; HIGA, O.Z. Biocompósitos de nitreto de silício: caracterização e avaliação biológica in vitro. In: CONGRESSO BRASILEIRO DE CERAMICA, 60., 15-18 de maio, 2016, Águas de Lindóia, SP. <b>Anais...</b> p. 1782-1793. Disponível em: http://repositorio.ipen.br/handle/123456789/26902.
dc.identifier.orcidhttps://orcid.org/0000-0002-5172-5082
dc.identifier.orcidhttps://orcid.org/0000-0002-3839-0839
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/26902
dc.local.eventoÁguas de Lindóia, SPpt_BR
dc.rightsopenAccesspt_BR
dc.subjectcomposite materials
dc.subjectevaluation
dc.subjectin vitro
dc.subjectsilicon nitrides
dc.subjectceramics
dc.subjectdoped materials
dc.subjectsilica
dc.subjectglass
dc.subjecttoxicity
dc.subjectadhesion
dc.subjectconnective tissue cells
dc.titleBiocompósitos de nitreto de silício: caracterização e avaliação biológica in vitropt_BR
dc.title.alternativeSilicon nitride biocomposites: characterization and in vitro biological evaluation
dc.typeTexto completo de eventopt_BR
dspace.entity.typePublication
ipen.autorOLGA ZAZUCO HIGA
ipen.autorTHIAGO DOS SANTOS FERREIRA
ipen.autorLUIS ANTONIO GENOVA
ipen.autorCECILIA CHAVES GUEDES E SILVA
ipen.codigoautor1023
ipen.codigoautor3402
ipen.codigoautor320
ipen.codigoautor2026
ipen.contributor.ipenauthorOLGA ZAZUCO HIGA
ipen.contributor.ipenauthorTHIAGO DOS SANTOS FERREIRA
ipen.contributor.ipenauthorLUIS ANTONIO GENOVA
ipen.contributor.ipenauthorCECILIA CHAVES GUEDES E SILVA
ipen.date.recebimento16-12pt_BR
ipen.event.datapadronizada2016pt_BR
ipen.identifier.ipendoc22761pt_BR
ipen.notas.internasAnais
ipen.type.genreArtigo
relation.isAuthorOfPublicationeeaeef03-7bd8-4788-ba3d-5c02800475bd
relation.isAuthorOfPublication334f8841-5c17-4cd1-995b-9cfaf53eb4dd
relation.isAuthorOfPublicatione7af24e8-0db9-49d2-8caf-92fd57c2686b
relation.isAuthorOfPublicationfd0f3d4e-e680-4e2c-a761-f459422bc266
relation.isAuthorOfPublication.latestForDiscoveryfd0f3d4e-e680-4e2c-a761-f459422bc266
sigepi.autor.atividadeGUEDES-SILVA, C.C.:2026:730:Spt_BR
sigepi.autor.atividadeGENOVA, L.A.:320:720:Npt_BR
sigepi.autor.atividadeFERREIRA, T.S.:3402:730:Npt_BR
sigepi.autor.atividadeHIGA, O.Z.:1023:820:Npt_BR
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