In vitro study of the composition and microhardness of the hard tissues from oral cavity submitted to gamma irradiation

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dc.contributor.authorPAREDES, WILBER E.B.
dc.contributor.authorARI, SANDRA F.
dc.contributor.authorGERALDO, AUREA B.C.
dc.contributor.authorANDRADE, DELVONEI A. de
dc.coverageInternacionalpt_BR
dc.creator.eventoWORLD CONGRESS ON CANCER THERAPY, 15thpt_BR
dc.date.accessioned2016-12-20T12:28:30Z
dc.date.available2016-12-20T12:28:30Z
dc.date.eventoDecember 5-7, 2016pt_BR
dc.description.abstractIntroduction: Clinical Radiotherapy is one of the most important techniques for the treatment of malignant lesions of the head and neck, however, exposure to ionizing radiation can lead to systemic complications or sites during and after radiation treatment. Among these immediate local complications in oral cavity, it stands out the xerostomia and consequent oral mucositis. Regarding late complications produced by radiation, decay of radiation and osteoradionecrosis, both dose-dependent lesions, which mostrate a high level of incidence in recent decades (1-30%) and unwieldy, although these are presented after completion of treatment and under the influence of local factors. Methodology: The methodology proposed in this study aims to examine the direct effect of ionizing radiation after gamma irradiation of enamel, root dentin and jawbone samples, through the dose rate used in patients suffering with head and neck cancer. The samples were analyzed by microhardness surface analysis, scanning electron microscopy (SEM) and Fourier transform infrared spectrometry (FTIR) before and after irradiation. Results and discussion: The data were analyzed statistically with a significance level of 95% (p <0.05%), through the parametric Student's t-test for related averages and ANOVA statistical test, finding a statistically significant result (p = 0.00) for the four groups of samples. Conclusion: From the statistical results, it is concluded that the effect of gamma radiation on hard tissues of the oral cavity was highly significant regarded to physical, compositional and morphological properties.pt_BR
dc.identifier.citationPAREDES, WILBER E.B.; ARI, SANDRA F.; GERALDO, AUREA B.C.; ANDRADE, DELVONEI A. de. In vitro study of the composition and microhardness of the hard tissues from oral cavity submitted to gamma irradiation. In: WORLD CONGRESS ON CANCER THERAPY, 15th, December 5-7, 2016, Philadelphia, USA. <b>Proceedings...</b> Disponível em: http://repositorio.ipen.br/handle/123456789/26920.
dc.identifier.orcidhttps://orcid.org/0000-0002-6689-3011
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/26920
dc.local.eventoPhiladelphia, USApt_BR
dc.rightsopenAccesspt_BR
dc.subjectin vitro
dc.subjectmicrohardness
dc.subjectanimal tissues
dc.subjectoral cavity
dc.subjectgamma radiation
dc.subjectradiotherapy
dc.subjectionizing radiations
dc.subjectbiological radiation effects
dc.subjectenamels
dc.subjectdentin
dc.subjectneoplasms
dc.subjectscanning electron microscopy
dc.subjectspectroscopy
dc.subjectclinical trials
dc.subjectswine
dc.subjectanimals
dc.subjectskeleton
dc.subjectbone tissues
dc.subjectteeth
dc.subjectosteoradionecrosis
dc.subjectjaw
dc.titleIn vitro study of the composition and microhardness of the hard tissues from oral cavity submitted to gamma irradiationpt_BR
dc.typeTexto completo de eventopt_BR
dspace.entity.typePublication
ipen.autorDELVONEI ALVES DE ANDRADE
ipen.autorAUREA BEATRIZ CERQUEIRA GERALDO
ipen.autorWILBER EDISON BERNAOLA PAREDES
ipen.codigoautor1258
ipen.codigoautor1466
ipen.codigoautor12706
ipen.contributor.ipenauthorDELVONEI ALVES DE ANDRADE
ipen.contributor.ipenauthorAUREA BEATRIZ CERQUEIRA GERALDO
ipen.contributor.ipenauthorWILBER EDISON BERNAOLA PAREDES
ipen.date.recebimento16-12pt_BR
ipen.event.datapadronizada2016pt_BR
ipen.identifier.ipendoc22778pt_BR
ipen.notas.internasProceedingspt_BR
ipen.type.genreArtigo
relation.isAuthorOfPublication0eeb4436-68e5-4573-a603-35f5fc912178
relation.isAuthorOfPublication825a6fc8-dbf1-471f-aeba-bedec4f0f7a3
relation.isAuthorOfPublication9b5f9837-2642-4d15-8feb-5631fab967fd
relation.isAuthorOfPublication.latestForDiscovery9b5f9837-2642-4d15-8feb-5631fab967fd
sigepi.autor.atividadePAREDES, WILBER E.B.:12706:920:Spt_BR
sigepi.autor.atividadeGERALDO, AUREA B.C.:1466:220:Npt_BR
sigepi.autor.atividadeANDRADE, DELVONEI A. DE:1258:420:Npt_BR
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