Infrared Spectroscopy evaluation of burn wound healing
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2019
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EUROPEAN CONFERENCES ON BIOMEDICAL OPTICS
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Resumo
Wound healing is a biological response in order to recover the tissue stability after injury. The impaired healing by thirddegree,
when the damage achieves the major part of dermis, is defined in four sequential and overlapping phases:
Inflammation, transition, proliferative and maturative1. The role of biochemical cascade associated in each phase are still
not fully understood, thus systematic evaluations tests are crucial. In fact, the gold standard to interrogate the molecular
signature of wound healing is concern on immunohistochemical analysis. This approach tends to be laborious, timeconsuming
and require multiple assays2. Since Fourier transform infrared spectroscopy (FTIR) has been demonstrated in
other studies to provide molecular change report upon biological samples, the present study aims to estimate the
feasibility of FTIR to discriminate healthy and burned skin throughout wound stages.
Como referenciar
CASTRO, PEDRO A.A. de; ZEZELL, DENISE M. Infrared Spectroscopy evaluation of burn wound healing: semi-quantitative study. In: QUINCY BROWN, J. (ed.); VAN LEEUWEN, TON G. (ed.). In: EUROPEAN CONFERENCES ON BIOMEDICAL OPTICS, June 23-27, 2019, Munich, Germany. Proceedings... Bellingham, WA, USA: SPIE, 2019. p. 1107304-1 - 1107304-4. (Proceedings of SPIE-OSA Vol. 11073, Clinical and Preclinical Optical Diagnostics II). DOI: 10.1117/12.2527051. Disponível em: http://repositorio.ipen.br/handle/123456789/30968. Acesso em: 27 Mar 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.