Identifying inflammatory signatures in heart tissue via FTIR and linear discriminant mapping

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dc.contributor.authorSTASI, RAFFAELE
dc.contributor.authorSILVA, DANIELA F.T.
dc.contributor.authorANJOS, VINICIUS P.
dc.contributor.authorMEDEI, EMILIANO H.
dc.contributor.authorZEZELL, DENISE M.
dc.coverageInternacional
dc.creator.eventoSBFoton International Optics and Photonics Conference (SBFoton IOPC)
dc.date.accessioned2026-03-20T19:19:08Z
dc.date.available2026-03-20T19:19:08Z
dc.date.eventoSeptember 21-24, 2025
dc.description.abstractFourier-transform infrared (FTIR) imaging spectroscopy was used to investigate biochemical alterations in cardiac tissue samples treated with Interleukin-1beta (IL-1β). Linear Discriminant Analysis (LDA) was applied to spectra in the 1500–1800 cm−1 region. In this work, the LDA component score for each pixel was plotted as a heatmap, enabling spatial visualization of spectral alterations. Heatmaps were generated for each of the three control and three treated samples. Additionally, the LDA loading curves show the induced alterations across wavenumbers.
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPQ)
dc.description.sponsorshipInstituto Nacional de Fotônica (INFO)
dc.description.sponsorshipMinistério da Ciência, Tecnologia, Inovações e Comunicações (MCTI)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIDCNPQ: 406761/2022-1
dc.description.sponsorshipIDINFO: 465763/2014- 6
dc.description.sponsorshipIDMCTI-SISFOTON: 440228/2021-2
dc.description.sponsorshipIDFAPESP: 21/00633-0
dc.description.sponsorshipIDCAPES: 88887.084317/2024-00
dc.event.siglaSBFoton IOPC
dc.format.extent1-3
dc.identifier.citationSTASI, RAFFAELE; SILVA, DANIELA F.T.; ANJOS, VINICIUS P.; MEDEI, EMILIANO H.; ZEZELL, DENISE M. Identifying inflammatory signatures in heart tissue via FTIR and linear discriminant mapping. In: SBFoton International Optics and Photonics Conference (SBFoton IOPC), September 21-24, 2025, São Pedro, SP. <b>Proceedings...</b> Piscataway, Nova Jersey: IEEE, 2025. p. 1-3. DOI: <a href="https://dx.doi.org/10.1109/SBFotonIOPC66433.2025.11274262">10.1109/SBFotonIOPC66433.2025.11274262</a>. Disponível em: https://repositorio.ipen.br/handle/123456789/49520.
dc.identifier.doi10.1109/SBFotonIOPC66433.2025.11274262
dc.identifier.orcidhttps://orcid.org/0000-0001-7404-9606
dc.identifier.urihttps://repositorio.ipen.br/handle/123456789/49520
dc.language.isoeng
dc.localPiscataway, Nova Jersey
dc.local.eventoSão Pedro, SP
dc.publisherIEEE
dc.rightsopenAccess
dc.titleIdentifying inflammatory signatures in heart tissue via FTIR and linear discriminant mapping
dc.typeTexto completo de evento
dspace.entity.typePublication
ipen.autorRAFFAELE STASI
ipen.autorDANIELA DE FATIMA TEIXEIRA DA SILVA
ipen.autorVINICIUS PEREIRA DOS ANJOS
ipen.autorDENISE MARIA ZEZELL
ipen.codigoautor16200
ipen.codigoautor2524
ipen.codigoautor16182
ipen.codigoautor693
ipen.contributor.ipenauthorRAFFAELE STASI
ipen.contributor.ipenauthorDANIELA DE FATIMA TEIXEIRA DA SILVA
ipen.contributor.ipenauthorVINICIUS PEREIRA DOS ANJOS
ipen.contributor.ipenauthorDENISE MARIA ZEZELL
ipen.event.datapadronizada2025
ipen.identifier.ipendoc31687
ipen.notas.internasProceedings
ipen.type.genreArtigo
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relation.isAuthorOfPublication1eeb6fee-14be-4973-9dcf-bc2b53a89aff
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relation.isAuthorOfPublication.latestForDiscovery84bbdbde-ef8c-4b06-a8ac-e7e8dea7429e
sigepi.autor.atividadeRAFFAELE STASI:16200:-1:N
sigepi.autor.atividadeDANIELA DE FATIMA TEIXEIRA DA SILVA:2524:920:N
sigepi.autor.atividadeVINICIUS PEREIRA DOS ANJOS:16182:-1:N
sigepi.autor.atividadeDENISE MARIA ZEZELL:693:920:N

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