THIAGO MARTINI PEREIRA
42 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 42
Resumo IPEN-doc 25745 Nanostructured synthetic hydroxyapatite and dental enamel heated e irradiated by Er,Cr:YSGG characterized by FTIR and XRD2009 - RABELO, J.S.; PEREIRA, T.M.; MAZZOCCHI, V.L.; VALERIO, M.E.G.; ZEZELL, D.M.The study evaluate the physical changes and/or chemical that occurs in synthetic hydroxyapatite (HAP) and in enamel under action of thermal heating in the furnace or laser irradiation of Er,Cr:YSGG that may cause changes in its structure to make them more resistant to demineralization aiming the formation of dental caries.Artigo IPEN-doc 27546 Evaluating biochemical differences in thyroglobulin from normal and goiter tissues by infrared spectral imaging2020 - PEREIRA, THIAGO M.; DIEM, MAX; BACHMANN, LUCIANO; BIRD, BENJAMIN; MILJKOVIC, MILOS; ZEZELL, DENISE M.Thyroglobulin is a glycoiodoprotein that is produced by thyroid follicular cells; it is stored in follicles in structures known as colloids. The main function of this protein is to stock the hormones triiodothyronine (T3) and thyroxine (T4) until the body requires them. This study aims to demonstrate that infrared spectral imaging with appropriate multivariate analysis can reveal biochemical changes in this glycoprotein. The results achieved herein point out biochemical differences in the colloid samples obtained from normal and goiter patients including glycosylation and changes in the secondary conformational structure. We have presented the first spectral histopathology-based method to detect biochemical differences in thyroid colloids, such as TG iodination, glycosylation, and changes in the secondary structure in normal and goiter patients. The observed changes in the colloids were mainly due to the alterations in amide I and amide II (secondary conformation of proteins) and there is a correlation with different glycosylation between normal and goiter tissues.Artigo IPEN-doc 27026 Caracterização por espectroscopia no infravermelho de colóides tireoidianos sadios e hiperplásicos2014 - PEREIRA, T.M.; DIEM, M.; BIRD, B.; MILJKOVIC, M.; ANA, P.A.; BACHMANN, L.; ZEZELL, D.M.O presente trabalho mostra a caracterização da Tiroglobulina contidos nos colóides tireoidianos por espectroscopia no infravermelho. A produção da tiroglobulina é alterada em pacientes com Bócio Nodular. Assim, as informações bioquímicas desta glicoiodoproteina podem ser utilizada como indicador desta disfunção. Os resultados utilizando espectroscopia no infravermelho revela diferenças bioquímicas nas conformação da proteína, hormônios e carboidratos.Resumo IPEN-doc 22905 Micro-FTIR can identify differences in cells from normal and abnormal thyroid follicular cells2016 - PEREIRA, T.M.; ZEZELL, D.M.; BIRD, B.; MILJKOVIC, M.; DIEM, M.Resumo IPEN-doc 22237 Monitoração de alterações na temperatura de dentes irradiados a laser por termopar e câmera termográfica2005 - PEREIRA, THIAGO M.; ANA, PATRICIA A. da; RIBEIRO, ADRIANA da C.; ZEZELL, DENISE M.Resumo IPEN-doc 22070 Monitoramento da temperatura em dentes irradiados a laser e LED's durante processo de clareamento dental2006 - PEREIRA, THIAGO M.; KABBACH, WILLIAM; KAUFFMAN, MARCELO F.; ZEZELL, DENISE M.Artigo IPEN-doc 20832 ATR-FTIR spectroscopy for the assessment of biochemical changes in skin due to cutaneous squamous cell carcinoma2015 - LIMA, CASSIO A.; GOULART, VIVIANE P.; CORREA, LUCIANA; PEREIRA, THIAGO M.; ZEZELL, DENISE M.Nonmelanoma skin cancers represent 95% of cutaneous neoplasms. Among them, squamous cell carcinoma (SCC) is the more aggressive form and shows a pattern of possible metastatic profile. In this work, we used Fourier transform infrared spectroscopy (FTIR) spectroscopy to assess the biochemical changes in normal skin caused by squamous cell carcinoma induced by multi-stage chemical carcinogenesis in mice. Changes in the absorption intensities and shifts were observed in the vibrational modes associated to proteins, indicating changes in secondary conformation in the neoplastic tissue. Hierarchical cluster analysis was performed to evaluate the potential of the technique to differentiate the spectra of neoplastic and normal skin tissue, so that the accuracy obtained for this classification was 86.4%. In this sense, attenuated total reflection (ATR)-FTIR spectroscopy provides a useful tool to complement histopathological analysis in the clinical routine for the diagnosis of cutaneous squamous cell carcinoma.Capítulo IPEN-doc 18002 Heat generation and transfer on biological tissues due to high-intensity laser irradiation2011 - ZEZELL, DENISE M.; ANA, PATRICIA A.; PEREIRA, THIAGO M.; CORREA, PAULO R.; VELLOSO JUNIOR, WALTERResumo IPEN-doc 14700 Tissue temperature variation in the use of surgical diode lasers2009 - VASQUES, M.A.T.; BENETTI, C.; ALVES, M.A.V.; PEREIRA, T.M.; ZEZELL, D.M.; CORREA, L.Resumo IPEN-doc 14424 Monitoracao da elevacao da temperatura durante o processo de clareamento dental2007 - PEREIRA, T.M.; BENETTI, C.; ZEZELL, D.M.