Iridium-192 seed development for ophthalmic cancer treatment
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2011
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INTERNATIONAL CONFERENCE ON DEVELOPMENT AND APPLICATIONS OF NUCLEAR TECHNOLOGIES
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Considered a public health problem in Brazil, cancer is the second leading cause of mortality
by disease, representing 13.2% of all deaths in the country [1]. Ophthalmic brachytherapy
involves inserting an acrylic plate with radioactive material in the eyes of a patient for
treatment of ocular tumors. This work is a partnership between Escola Paulista de Medicina -
UNIFESP and the Instituto de Pesquisas Energéticas e Nucleares - IPEN for development and
implementation of a cheaper therapeutic treatment for ophthalmic cancer with a iridium-192
source, to attend a greater number of patients. Iridium-192 is produced in nuclear reactor. It
has a half-life of 74.2 days and decays by beta emission with average energy of 370 keV.[2,3].
The seed will be a platinum-iridium alloy core (80/20), encapsulated in a titanium tube [4].
This project will be divided into the following steps: characterization of materials by FRX (X-ray
fluorescence) e EDS (Energy Dispersive Spectroscopy); iridium irradiation in the nuclear
reactor IEA-R1; sealing of iridium-192 seed; leakage tests of iridium-192 source in
accordance with standard ISO-9978 (radiation protection- Sealed radioactive sources-
Leakage test methods) [5]; metallographic tests and measure the activity of the source. The
evaluation for use in the ophthalmic treatment of cancer will be made later.
Como referenciar
ROSTELATO, M.E.C.M.; MATTOS, F.R.; ZEITUNI, C.A.; SOUZA, C.D.; MOURA, J.A.; MOURA, E.S.; FEHER, A.; COSTA, O.L.; PELEIAS JUNIOR, F.S.; MARQUES, J.R.O.; BELFORT NETO, R. Iridium-192 seed development for ophthalmic cancer treatment. In: DUDALA, JOANNA (ed.); STEGOWSKI, ZDZISLAW (ed.). In: INTERNATIONAL CONFERENCE ON DEVELOPMENT AND APPLICATIONS OF NUCLEAR TECHNOLOGIES, September 11-14, 2011, Krakow, Poland. Abstract... Krakow, Poland: Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, 2011. p. 144-144. Disponível em: http://repositorio.ipen.br/handle/123456789/33339. Acesso em: 09 May 2024.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.