Silicon nitride with titania, calcia and silica additives for orthopaedic applications
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2020
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Processing and Application of Ceramics
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Abstract
Titanium, silicon and calcium ions have demonstrated positive effects in bone healing. Therefore, this paper
investigates the densification, mechanical properties and in vitro biological behaviour of TiO2, together with
SiO2 and CaO, on silicon nitride ceramics to be used in clinical applications. The results revealed that the
sintered samples reached high values of relative density and fracture toughness, non-cytotoxicity as well as
good ability to promote cell proliferation and form a layer of carbonated hydroxyapatite on their surfaces,
after immersion in simulated body fluid. The sample with the highest amount of TiO2 reached the highest value
of relative density and the best results of cell proliferation and fracture toughness, indicating the great potential
to be explored by in vivo experiments for later application as intervertebral devices.
Citation
GUEDES-SILVA, CECILIA C.; RODAS, ANDREA C.D.; CARVALHO, FLAVIO M.S.; HIGA, OLGA Z.; FERREIRA, THIAGO S. Silicon nitride with titania, calcia and silica additives for orthopaedic applications. Processing and Application of Ceramics, v. 14, n. 1, p. 63-70, 2020. DOI: 10.2298/PAC2001063G. DisponÃvel em: http://repositorio.ipen.br/handle/123456789/31421. Acesso em: 16 Mar 2025.
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