LUIS ALBERTO PEREIRA DIAS
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Resumo IPEN-doc 30934 Specific methodology to analyse the activity meters performance inside the hot cell2024 - MARTINS, ELAINE W.; POTIENS, MARIA da P.A.; DIAS, LUIS A.P.Introduction: The Instrument Calibration Laboratory (LCI) at IPEN responsible for developing andimplementing calibration methodologies for various types of instruments used in the nuclear field andrelated areas. Its main responsibilities include conducting precise and traceable calibrations to ensure theaccuracy and reliability of equipment, such as activimeters used in nuclear medicine services (NMS).Additionally, LCI promotes the continuous development of new calibration methodologies, including “insitu” approaches that allow instruments to be calibrated at their actual point of use. It also maintainsstandards and procedures to ensure that measurements performed are comparable and traceable tointernational standards. LCI provides specialized support to critical sectors such as nuclear medicine,where accurate measurements of radioactivity are essential for safe and effective diagnostics andtreatments. It collaborates with research institutions, universities, and industries, offering calibrationservices to both the public and private sectors. The National Commission of Nuclear Energy establishesthat each nuclear medicine service have at least one activimeter, under a periodic testing as a part of aquality program to ensure reliable results. Calibration factors must be traceable for each radionuclide, asinaccurate measurements can introduce uncertainties that directly affect diagnostics and therapies.Activimeters, crucial in these practices, are often located in controlled and hard-to-access areas,complicating both their handling and transport to specialized laboratories for calibration. To address thischallenge, LCI has developed in situ calibration methodologies where the radiopharmaceutical itselfserves as the reference source. Objective: This study aimed to develop and implement a methodology for the control and calibration ofactivimeters using radionuclides produced by the Radiopharmaceutical Production Center at IPEN. Themethodology simplifies the procedure by transporting only the radioactive samples, without the need tomove the activimeter itself, thereby preserving the quality and accuracy of measurements. Materials and Methods: Since the development of the new methodology and the execution of this work,all steps for calibrating activimeters have been based on the methodology applied at the National PhysicalLaboratory (NPL), UK. Eleven activimeters from the Radiopharmaceutical Production Sector of IPENwere tested using radionuclides 99mTc, 123I, 131I, 111In, and 67Ga. Calibration factors were determined foreach dose activimeter. Results and Conclusions: After applying the methodology by qualified technicians, the results obtainedfrom the tested activimeters demonstrated their significance, as calibration factors could show correctionsof up to 5% for each tested radionuclide.