AMANDA CRISTINA MAZER

AMANDA CRISTINA MAZER

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Avaliação de registro de imagem realizado com e sem pontos de referência extraídos através da técnica SIFT
2022 - MAZER, AMANDA C.; YORIYAZ, HELIO
Em Radioterapia Guiada por Imagem (IGRT), é comum a aquisição de diversas imagens de um paciente e, por consequência, a realização de registro de imagem para a comparação entre elas. Devido a isso, é fundamental que sejam realizados tanto um bom registro quanto um bom controle da qualidade (CQ) do registro. O objetivo deste trabalho é avaliar um registro de imagem quando realizado com e sem pontos de referência. Para isso, imagens de Tomografia Computadorizada (TC) de um paciente da radioterapia foram utilizadas para realizar registros rígido e elástico, com e sem pontos de referência. A técnica Scale Invariant Feature Transform (SIFT) foi utilizada para desenvolver um algoritmo para a extração semi-automática de pontos-chave estáveis das imagens, tanto para os registros quanto para a avaliação de tais registros. Através dos valores de erro médio, erro máximo e Informação Mútua (IM) encontrados, foi possível verificar um melhor alinhamento das imagens quando realizado o registro partindo inicialmente dos pontos de referência extraídos, em comparação com o alinhamento realizado sem esses pontos de referência. A SIFT mostrou ser uma ótima ferramenta para realizar ambas as tarefas e, quando possível, o profissional da clínica deve realizar um bom CQ quantitativo de registro, considerando pontos de referência distribuídos pelas imagens.
Rigid and deformable Image registration analysis in radiation therapy based on SIFT method
2021 - MAZER, A.C.; YORIYAZ, H
Interpolation studies of a 3D dosimetric system for quality assurance in radiation therapy
2019 - MAZER, AMANDA C; SHORTO, JULIAN M.B.; SIQUEIRA, PAULO T.D.; NAKANDAKARI, MARCOS V.N.; RIBEIRO, VICTOR A.B.; YORIYAZ, HELIO
With the evolution of radiation therapy techniques, treatments have become increasingly accurate. To ensure a good quality assurance program for modern equipment, Sun Nuclear Corporation has developed ArcCHECK, a 3D dosimetric system, which contains 1386 helically arranged diodes within a PMMA cylindrical structure. The outputs of this system show, in addition to dose values acquired directly from the diodes, also matrices with interpolated dose values, in order to provide values at more than 5000 points for quality assurance. The main purpose of this work is to analyze the interpolated dose values provided by ArcCHECK. For this, simple measurements were taken with ArcCHECK, with a 10x10 cm2 static field of 6 MeV photons and 100 MU. A algorithm for MATLAB software was also developed so that it was possible to interpolate crude dose values obtained from the diodes and compare them with the values interpolated by the dosimetric system software. Significant dose differences values were found in the relative dose difference between the matrices interpolated by the algorithm and by ArcCHECK. The method used by this dosimetric system presented a diode selection pattern for the interpolation and different when compared to the developed method, even if both were calculated in the 2D plane, based on the dose map acquired by ArcCHECK.
Study of a 3D dosimetry system response – ARCCHECK®
2017 - MAZER, AMANDA C.; NAKANDAKARI, MARCOS V.N.; YORIYAZ, HELIO
Ionizing radiation therapies have improved over the years, becoming more specific for each patient. Thereby as the treatment planning system (TPS) complexities increases, the quality assurance (QA) methods have to be in a constant evolution. One of the techniques that demand great complexity is the Volumetric Modulated Arc Therapy (VMAT). One possible way to VMAT commissioning is using 3D dosimetry systems and recently a new 3D dosimetry system called ArcCheck had been developed and commercialized mainly for VMAT quality assurance. It is water-equivalent and composed by an array of 1386 diodes arranged in a spiral pattern. Since simulation methods, like Monte Carlo method, ensure highly accurate results, MCNP (A General Monte Carlo N-Particle Transport Code System) is totally reliable for problems that involve radiation transport. This work presents a preliminary study of the 3D dosimetry system ArcCheck by developing two computational models in MCNP6. In addition, experimental measures were acquired using the ArcCheck in a Linear Accelerator and then these values were compared with the results obtained by simulations of both models. The comparisons showed good reproducibility.